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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

Xu, Daichao ; Jin, Taijie ; Zhu, Hong ; Chen, Hongbo ; Ofengeim, Dimitry ; Zou, Chengyu ; Mifflin, Lauren ; Pan, Lifeng ; Amin, Palak ; Li, Wanjin ; Shan, Bing ; Naito, Masanori Gomi ; Meng, Huyan ; Li, Ying ; Pan, Heling ; Aron, Liviu ; Adiconis, Xian ; Levin, Joshua Z. ; Yankner, Bruce A. ; Yuan, Junying

Cell, 2018-09, Vol.174 (6), p.1477-1491.e19 [Periódico revisado por pares]

United States: Elsevier Inc

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2
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
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MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death

Dondelinger, Yves ; Delanghe, Tom ; Rojas-Rivera, Diego ; Priem, Dario ; Delvaeye, Tinneke ; Bruggeman, Inge ; Van Herreweghe, Franky ; Vandenabeele, Peter ; Bertrand, Mathieu J M

Nature cell biology, 2017-10, Vol.19 (10), p.1237-1247 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
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Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Annibaldi, Alessandro ; Wicky John, Sidonie ; Vanden Berghe, Tom ; Swatek, Kirby N. ; Ruan, Jianbin ; Liccardi, Gianmaria ; Bianchi, Katiuscia ; Elliott, Paul R. ; Choi, Sze Men ; Van Coillie, Samya ; Bertin, John ; Wu, Hao ; Komander, David ; Vandenabeele, Peter ; Silke, John ; Meier, Pascal

Molecular cell, 2018-02, Vol.69 (4), p.566-580.e5 [Periódico revisado por pares]

United States: Elsevier Inc

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4
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation
RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation
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RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

Liccardi, Gianmaria ; Ramos Garcia, Laura ; Tenev, Tencho ; Annibaldi, Alessandro ; Legrand, Arnaud J. ; Robertson, David ; Feltham, Rebecca ; Anderton, Holly ; Darding, Maurice ; Peltzer, Nieves ; Dannappel, Marius ; Schünke, Hannah ; Fava, Luca L. ; Haschka, Manuel D. ; Glatter, Timo ; Nesvizhskii, Alexey ; Schmidt, Alexander ; Harris, Philip A. ; Bertin, John ; Gough, Peter J. ; Villunger, Andreas ; Silke, John ; Pasparakis, Manolis ; Bianchi, Katiuscia ; Meier, Pascal

Molecular cell, 2019-02, Vol.73 (3), p.413-428.e7 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling
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Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

Hrdinka, Matous ; Schlicher, Lisa ; Dai, Bing ; Pinkas, Daniel M ; Bufton, Joshua C ; Picaud, Sarah ; Ward, Jennifer A ; Rogers, Catherine ; Suebsuwong, Chalada ; Nikhar, Sameer ; Cuny, Gregory D ; Huber, Kilian VM ; Filippakopoulos, Panagis ; Bullock, Alex N ; Degterev, Alexei ; Gyrd‐Hansen, Mads

The EMBO journal, 2018-09, Vol.37 (17), p.n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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6
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models
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Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models

Zhou, Ting ; Wang, Qiwei ; Phan, Noel ; Ren, Jun ; Yang, Huan ; Feldman, Conner C ; Feltenberger, John B ; Ye, Zhengqing ; Wildman, Scott A ; Tang, Weiping ; Liu, Bo

Cell death & disease, 2019-03, Vol.10 (3), p.226, Article 226 [Periódico revisado por pares]

England: Springer Nature B.V

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7
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
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Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Lupfer, Christopher ; Thomas, Paul G ; Anand, Paras K ; Vogel, Peter ; Milasta, Sandra ; Martinez, Jennifer ; Huang, Gonghua ; Green, Maggie ; Kundu, Mondira ; Chi, Hongbo ; Xavier, Ramnik J ; Green, Douglas R ; Lamkanfi, Mohamed ; Dinarello, Charles A ; Doherty, Peter C ; Kanneganti, Thirumala-Devi

Nature immunology, 2013-05, Vol.14 (5), p.480-488 [Periódico revisado por pares]

United States: Nature Publishing Group

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8
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
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A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Nachbur, Ueli ; Stafford, Che A ; Bankovacki, Aleksandra ; Zhan, Yifan ; Lindqvist, Lisa M ; Fiil, Berthe K ; Khakham, Yelena ; Ko, Hyun-Ja ; Sandow, Jarrod J ; Falk, Hendrik ; Holien, Jessica K ; Chau, Diep ; Hildebrand, Joanne ; Vince, James E ; Sharp, Phillip P ; Webb, Andrew I ; Jackman, Katherine A ; Mühlen, Sabrina ; Kennedy, Catherine L ; Lowes, Kym N ; Murphy, James M ; Gyrd-Hansen, Mads ; Parker, Michael W ; Hartland, Elizabeth L ; Lew, Andrew M ; Huang, David C S ; Lessene, Guillaume ; Silke, John

Nature communications, 2015-03, Vol.6 (1), p.6442-6442, Article 6442 [Periódico revisado por pares]

England: Nature Publishing Group

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9
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

Boege, Yannick ; Malehmir, Mohsen ; Healy, Marc E. ; Bettermann, Kira ; Lorentzen, Anna ; Vucur, Mihael ; Ahuja, Akshay K. ; Böhm, Friederike ; Mertens, Joachim C. ; Shimizu, Yutaka ; Frick, Lukas ; Remouchamps, Caroline ; Mutreja, Karun ; Kähne, Thilo ; Sundaravinayagam, Devakumar ; Wolf, Monika J. ; Rehrauer, Hubert ; Koppe, Christiane ; Speicher, Tobias ; Padrissa-Altés, Susagna ; Maire, Renaud ; Schattenberg, Jörn M. ; Jeong, Ju-Seong ; Liu, Lei ; Zwirner, Stefan ; Boger, Regina ; Hüser, Norbert ; Davis, Roger J. ; Müllhaupt, Beat ; Moch, Holger ; Schulze-Bergkamen, Henning ; Clavien, Pierre-Alain ; Werner, Sabine ; Borsig, Lubor ; Luther, Sanjiv A. ; Jost, Philipp J. ; Weinlich, Ricardo ; Unger, Kristian ; Behrens, Axel ; Hillert, Laura ; Dillon, Christopher ; Di Virgilio, Michela ; Wallach, David ; Dejardin, Emmanuel ; Zender, Lars ; Naumann, Michael ; Walczak, Henning ; Green, Douglas R. ; Lopes, Massimo ; Lavrik, Inna ; Luedde, Tom ; Heikenwalder, Mathias ; Weber, Achim

Cancer cell, 2017-09, Vol.32 (3), p.342-359.e10 [Periódico revisado por pares]

United States: Elsevier Inc

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10
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis
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NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

Pandey, Amit K ; Yang, Yibin ; Jiang, Zhaozhao ; Fortune, Sarah M ; Coulombe, Francois ; Behr, Marcel A ; Fitzgerald, Katherine A ; Sassetti, Christopher M ; Kelliher, Michelle A Cossart, Pascale

PLoS pathogens, 2009-07, Vol.5 (7), p.e1000500-e1000500 [Periódico revisado por pares]

United States: Public Library of Science

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