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Material Type: Artigo
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Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrilsDauer née Joppe, Karina ; Tatenhorst, Lars ; Caldi Gomes, Lucas ; Zhang, Shuyu ; Parvaz, Mojan ; Carboni, Eleonora ; Roser, Anna‐Elisa ; El DeBakey, Hazem ; Bähr, Mathias ; Vogel‐Mikuš, Katarina ; Wang Ip, Chi ; Becker, Stefan ; Zweckstetter, Markus ; Lingor, PaulJournal of neurochemistry, 2021-11, Vol.159 (3), p.554-573 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathiesVillar‐Piqué, Anna ; Lopes da Fonseca, Tomás ; Outeiro, Tiago FlemingJournal of neurochemistry, 2016-10, Vol.139 (S1), p.240-255 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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The contribution of alpha synuclein to neuronal survival and function – Implications for Parkinson's diseaseBenskey, Matthew J. ; Perez, Ruth G. ; Manfredsson, Fredric P.Journal of neurochemistry, 2016-05, Vol.137 (3), p.331-359 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathiesVicente Miranda, Hugo ; Szego, Éva M ; Oliveira, Luís M A ; Breda, Carlo ; Darendelioglu, Ekrem ; de Oliveira, Rita M ; Ferreira, Diana G ; Gomes, Marcos A ; Rott, Ruth ; Oliveira, Márcia ; Munari, Francesca ; Enguita, Francisco J ; Simões, Tânia ; Rodrigues, Eva F ; Heinrich, Michael ; Martins, Ivo C ; Zamolo, Irina ; Riess, Olaf ; Cordeiro, Carlos ; Ponces-Freire, Ana ; Lashuel, Hilal A ; Santos, Nuno C ; Lopes, Luisa V ; Xiang, Wei ; Jovin, Thomas M ; Penque, Deborah ; Engelender, Simone ; Zweckstetter, Markus ; Klucken, Jochen ; Giorgini, Flaviano ; Quintas, Alexandre ; Outeiro, Tiago FBrain (London, England : 1878), 2017-05, Vol.140 (5), p.1399-1419 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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In vitro models of synucleinopathies: informing on molecular mechanisms and protective strategiesMarvian, Amir Tayaranian ; Koss, David J. ; Aliakbari, Farhang ; Morshedi, Dina ; Outeiro, Tiago FlemingJournal of neurochemistry, 2019-09, Vol.150 (5), p.535-565 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Systemic Exosomal Delivery of shRNA Minicircles Prevents Parkinsonian PathologyIzco, María ; Blesa, Javier ; Schleef, Martin ; Schmeer, Marco ; Porcari, Riccardo ; Al-Shawi, Raya ; Ellmerich, Stephan ; de Toro, María ; Gardiner, Chris ; Seow, Yiqi ; Reinares-Sebastian, Alejandro ; Forcen, Raquel ; Simons, J. Paul ; Bellotti, Vittorio ; Cooper, J. Mark ; Alvarez-Erviti, LydiaMolecular therapy, 2019-12, Vol.27 (12), p.2111-2122 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered MonomerFauvet, Bruno ; Mbefo, Martial K. ; Fares, Mohamed-Bilal ; Desobry, Carole ; Michael, Sarah ; Ardah, Mustafa T. ; Tsika, Elpida ; Coune, Philippe ; Prudent, Michel ; Lion, Niels ; Eliezer, David ; Moore, Darren J. ; Schneider, Bernard ; Aebischer, Patrick ; El-Agnaf, Omar M. ; Masliah, Eliezer ; Lashuel, Hilal A.The Journal of biological chemistry, 2012-05, Vol.287 (19), p.15345-15364 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Alpha synuclein, the culprit in Parkinson disease, is required for normal immune functionAlam, Md Masud ; Yang, De ; Li, Xiao-Qing ; Liu, Jia ; Back, Timothy Carrel ; Trivett, Anna ; Karim, Baktiar ; Barbut, Denise ; Zasloff, Michael ; Oppenheim, Joost J.Cell reports (Cambridge), 2022-01, Vol.38 (2), p.110090-110090, Article 110090 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Intracranial administration of alpha-synuclein fibrils in A30P-synuclein transgenic mice causes robust synucleinopathy and microglial inductionGentzel, Renee C ; Toolan, Dawn ; Jinn, Sarah ; Schachter, Joel B ; Ma, Lei ; Kahle, Philipp J ; Smith, Sean M ; Marcus, Jacob NNeurobiology of aging, 2021-10, Vol.106, p.12-25 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Neurodegeneration and the ordered assembly of α-synucleinSpillantini, Maria Grazia ; Goedert, MichelCell and tissue research, 2018-07, Vol.373 (1), p.137-148 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |