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Material Type: Artigo
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Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long termRey, Nolwen L. ; George, Sonia ; Steiner, Jennifer A. ; Madaj, Zachary ; Luk, Kelvin C. ; Trojanowski, John Q. ; Lee, Virginia M.-Y. ; Brundin, PatrikActa neuropathologica, 2018-01, Vol.135 (1), p.65-83 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ PathologyBassil, Fares ; Brown, Hannah J. ; Pattabhiraman, Shankar ; Iwasyk, Joe E. ; Maghames, Chantal M. ; Meymand, Emily S. ; Cox, Timothy O. ; Riddle, Dawn M. ; Zhang, Bin ; Trojanowski, John Q. ; Lee, Virginia M.-Y.Neuron (Cambridge, Mass.), 2020-01, Vol.105 (2), p.260-275.e6 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Alpha‐synuclein at the nexus of genes and environment: the impact of environmental enrichment and stress on brain health and diseaseWassouf, Zinah ; Schulze‐Hentrich, Julia M.Journal of neurochemistry, 2019-09, Vol.150 (5), p.591-604 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Definition of a molecular pathway mediating α-synuclein neurotoxicityBurré, Jacqueline ; Sharma, Manu ; Südhof, Thomas CThe Journal of neuroscience, 2015-04, Vol.35 (13), p.5221-5232 [Periódico revisado por pares]United States: Society for NeuroscienceTexto completo disponível |
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Material Type: Artigo
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Crowded organelles, lipid accumulation, and abnormal membrane tubulation in cellular models of enhanced α-synuclein membrane interactionEricsson, Maria ; von Saucken, Victoria ; Newman, Andrew J. ; Doehr, Lena ; Hoesch, Camilla ; Kim, Tae-Eun ; Dettmer, UlfBrain research, 2021-05, Vol.1758, p.147349-147349, Article 147349 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s diseaseGarcia-Reitböck, Pablo ; Anichtchik, Oleg ; Bellucci, Arianna ; Iovino, Mariangela ; Ballini, Chiara ; Fineberg, Elena ; Ghetti, Bernardino ; Della Corte, Laura ; Spano, PierFranco ; Tofaris, George K. ; Goedert, Michel ; Spillantini, Maria GraziaBrain (London, England : 1878), 2010-07, Vol.133 (7), p.2032-2044 [Periódico revisado por pares]Oxford: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson’s DiseaseNuber, Silke ; Rajsombath, Molly ; Minakaki, Georgia ; Winkler, Jürgen ; Müller, Christian P. ; Ericsson, Maria ; Caldarone, Barbara ; Dettmer, Ulf ; Selkoe, Dennis J.Neuron (Cambridge, Mass.), 2018-10, Vol.100 (1), p.75-90.e5 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathologySheehan, Patrick W. ; Nadarajah, Collin J. ; Kanan, Michael F. ; Patterson, Jessica N. ; Novotny, Brenna ; Lawrence, Jennifer H. ; King, Melvin W. ; Brase, Logan ; Inman, Casey E. ; Yuede, Carla M. ; Lee, Jiyeon ; Patel, Tirth K. ; Harari, Oscar ; Benitez, Bruno A. ; Davis, Albert A. ; Musiek, Erik S.Neuron (Cambridge, Mass.), 2023-08, Vol.111 (15), p.2383-2398.e7 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's diseaseRusso, Marco J ; Orru, Christina D ; Concha-Marambio, Luis ; Giaisi, Simone ; Groveman, Bradley R ; Farris, Carly M ; Holguin, Bret ; Hughson, Andrew G ; LaFontant, David-Erick ; Caspell-Garcia, Chelsea ; Coffey, Christopher S ; Mollon, Jennifer ; Hutten, Samantha J ; Merchant, Kalpana ; Heym, Roland G ; Soto, Claudio ; Caughey, Byron ; Kang, Un JungActa neuropathologica communications, 2021-11, Vol.9 (1), p.179-13, Article 179 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
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Material Type: Artigo
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Increased telomerase improves motor function and alpha-synuclein pathology in a transgenic mouse model of Parkinson’s disease associated with enhanced autophagyWan, Tengfei ; Weir, Emma J. ; Johnson, Mary ; Korolchuk, Viktor I. ; Saretzki, Gabriele C.Progress in neurobiology, 2021-04, Vol.199, p.101953, Article 101953 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |