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Material Type: Artigo
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Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathiesVillar‐Piqué, Anna ; Lopes da Fonseca, Tomás ; Outeiro, Tiago FlemingJournal of neurochemistry, 2016-10, Vol.139 (S1), p.240-255 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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The contribution of alpha synuclein to neuronal survival and function – Implications for Parkinson's diseaseBenskey, Matthew J. ; Perez, Ruth G. ; Manfredsson, Fredric P.Journal of neurochemistry, 2016-05, Vol.137 (3), p.331-359 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernelLi, Binsen ; Ge, Peng ; Murray, Kevin A ; Sheth, Phorum ; Zhang, Meng ; Nair, Gayatri ; Sawaya, Michael R ; Shin, Woo Shik ; Boyer, David R ; Ye, Shulin ; Eisenberg, David S ; Zhou, Z Hong ; Jiang, LinNature communications, 2018-09, Vol.9 (1), p.3609-10, Article 3609 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathiesVicente Miranda, Hugo ; Szego, Éva M ; Oliveira, Luís M A ; Breda, Carlo ; Darendelioglu, Ekrem ; de Oliveira, Rita M ; Ferreira, Diana G ; Gomes, Marcos A ; Rott, Ruth ; Oliveira, Márcia ; Munari, Francesca ; Enguita, Francisco J ; Simões, Tânia ; Rodrigues, Eva F ; Heinrich, Michael ; Martins, Ivo C ; Zamolo, Irina ; Riess, Olaf ; Cordeiro, Carlos ; Ponces-Freire, Ana ; Lashuel, Hilal A ; Santos, Nuno C ; Lopes, Luisa V ; Xiang, Wei ; Jovin, Thomas M ; Penque, Deborah ; Engelender, Simone ; Zweckstetter, Markus ; Klucken, Jochen ; Giorgini, Flaviano ; Quintas, Alexandre ; Outeiro, Tiago FBrain (London, England : 1878), 2017-05, Vol.140 (5), p.1399-1419 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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The many faces of α-synuclein: from structure and toxicity to therapeutic targetLashuel, Hilal A ; Overk, Cassia R ; Oueslati, Abid ; Masliah, EliezerNature reviews. Neuroscience, 2013-01, Vol.14 (1), p.38-48 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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α-Synuclein strains cause distinct synucleinopathies after local and systemic administrationPeelaerts, W ; Bousset, L ; Van der Perren, A ; Moskalyuk, A ; Pulizzi, R ; Giugliano, M ; Van den Haute, C ; Melki, R ; Baekelandt, VNature (London), 2015-06, Vol.522 (7556), p.340-344 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Alpha-Synuclein as a Biomarker for Parkinson's DiseaseAtik, Anzari ; Stewart, Tessandra ; Zhang, JingBrain pathology (Zurich, Switzerland), 2016-05, Vol.26 (3), p.410-418 [Periódico revisado por pares]Switzerland: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeysRecasens, Ariadna ; Dehay, Benjamin ; Bové, Jordi ; Carballo-Carbajal, Iria ; Dovero, Sandra ; Pérez-Villalba, Ana ; Fernagut, Pierre-Olivier ; Blesa, Javier ; Parent, Annabelle ; Perier, Celine ; Fariñas, Isabel ; Obeso, José A. ; Bezard, Erwan ; Vila, MiquelAnnals of neurology, 2014-03, Vol.75 (3), p.351-362 [Periódico revisado por pares]United States: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Structural and functional characterization of two alpha-synuclein strainsBousset, Luc ; Pieri, Laura ; Ruiz-Arlandis, Gemma ; Gath, Julia ; Jensen, Poul Henning ; Habenstein, Birgit ; Madiona, Karine ; Olieric, Vincent ; Böckmann, Anja ; Meier, Beat H ; Melki, RonaldNature communications, 2013-10, Vol.4 (1), p.2575-2575, Article 2575 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling NanotubesRostami, Jinar ; Holmqvist, Staffan ; Lindström, Veronica ; Sigvardson, Jessica ; Westermark, Gunilla T ; Ingelsson, Martin ; Bergström, Joakim ; Roybon, Laurent ; Erlandsson, AnnaThe Journal of neuroscience, 2017-12, Vol.37 (49), p.11835-11853 [Periódico revisado por pares]United States: Society for NeuroscienceTexto completo disponível |