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1 |
Material Type: Artigo
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Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophyShahnawaz, Mohammad ; Mukherjee, Abhisek ; Pritzkow, Sandra ; Mendez, Nicolas ; Rabadia, Prakruti ; Liu, Xiangan ; Hu, Bo ; Schmeichel, Ann ; Singer, Wolfgang ; Wu, Gang ; Tsai, Ah-Lim ; Shirani, Hamid ; Nilsson, K Peter R ; Low, Phillip A ; Soto, ClaudioNature (London), 2020-02, Vol.578 (7794), p.273-277 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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α-Synuclein strains cause distinct synucleinopathies after local and systemic administrationPeelaerts, W ; Bousset, L ; Van der Perren, A ; Moskalyuk, A ; Pulizzi, R ; Giugliano, M ; Van den Haute, C ; Melki, R ; Baekelandt, VNature (London), 2015-06, Vol.522 (7556), p.340-344 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
3 |
Material Type: Artigo
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Structures of α-synuclein filaments from multiple system atrophySchweighauser, Manuel ; Shi, Yang ; Tarutani, Airi ; Kametani, Fuyuki ; Murzin, Alexey G ; Ghetti, Bernardino ; Matsubara, Tomoyasu ; Tomita, Taisuke ; Ando, Takashi ; Hasegawa, Kazuko ; Murayama, Shigeo ; Yoshida, Mari ; Hasegawa, Masato ; Scheres, Sjors H W ; Goedert, MichelNature (London), 2020-09, Vol.585 (7825), p.464-469 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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Alpha-Synuclein as a Biomarker for Parkinson's DiseaseAtik, Anzari ; Stewart, Tessandra ; Zhang, JingBrain pathology (Zurich, Switzerland), 2016-05, Vol.26 (3), p.410-418 [Periódico revisado por pares]Switzerland: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeysRecasens, Ariadna ; Dehay, Benjamin ; Bové, Jordi ; Carballo-Carbajal, Iria ; Dovero, Sandra ; Pérez-Villalba, Ana ; Fernagut, Pierre-Olivier ; Blesa, Javier ; Parent, Annabelle ; Perier, Celine ; Fariñas, Isabel ; Obeso, José A. ; Bezard, Erwan ; Vila, MiquelAnnals of neurology, 2014-03, Vol.75 (3), p.351-362 [Periódico revisado por pares]United States: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered MonomerFauvet, Bruno ; Mbefo, Martial K. ; Fares, Mohamed-Bilal ; Desobry, Carole ; Michael, Sarah ; Ardah, Mustafa T. ; Tsika, Elpida ; Coune, Philippe ; Prudent, Michel ; Lion, Niels ; Eliezer, David ; Moore, Darren J. ; Schneider, Bernard ; Aebischer, Patrick ; El-Agnaf, Omar M. ; Masliah, Eliezer ; Lashuel, Hilal A.The Journal of biological chemistry, 2012-05, Vol.287 (19), p.15345-15364 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathiesPeng, Chao ; Gathagan, Ronald J ; Covell, Dustin J ; Medellin, Coraima ; Stieber, Anna ; Robinson, John L ; Zhang, Bin ; Pitkin, Rose M ; Olufemi, Modupe F ; Luk, Kelvin C ; Trojanowski, John Q ; Lee, Virginia M-YNature (London), 2018-05, Vol.557 (7706), p.558-563 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
8 |
Material Type: Artigo
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Structures of α-synuclein filaments from human brains with Lewy pathologyYang, Yang ; Shi, Yang ; Schweighauser, Manuel ; Zhang, Xianjun ; Kotecha, Abhay ; Murzin, Alexey G ; Garringer, Holly J ; Cullinane, Patrick W ; Saito, Yuko ; Foroud, Tatiana ; Warner, Thomas T ; Hasegawa, Kazuko ; Vidal, Ruben ; Murayama, Shigeo ; Revesz, Tamas ; Ghetti, Bernardino ; Hasegawa, Masato ; Lashley, Tammaryn ; Scheres, Sjors H W ; Goedert, MichelNature (London), 2022-10, Vol.610 (7933), p.791-795 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
9 |
Material Type: Artigo
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Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formationChen, Serene W. ; Drakulic, Srdja ; Deas, Emma ; Ouberai, Myriam ; Aprile, Francesco A. ; Arranz, Rocío ; Ness, Samuel ; Roodveldt, Cintia ; Guilliams, Tim ; De-Genst, Erwin J. ; Klenerman, David ; Wood, Nicholas W. ; Knowles, Tuomas P.J. ; Alfonso, Carlos ; Rivas, Germán ; Abramov, Andrey Y. ; Valpuesta, José María ; Dobson, Christopher M. ; Cremades, NuniloProceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.E1994-E2003 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
10 |
Material Type: Artigo
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Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomersFusco, Giuliana ; Chen, Serene W. ; Williamson, Philip T. F. ; Cascella, Roberta ; Perni, Michele ; Jarvis, James A. ; Cecchi, Cristina ; Vendruscolo, Michele ; Chiti, Fabrizio ; Cremades, Nunilo ; Ying, Liming ; Dobson, Christopher M. ; De Simone, AlfonsoScience (American Association for the Advancement of Science), 2017-12, Vol.358 (6369), p.1440-1443 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |