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11 |
Material Type: Artigo
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GRaSP-web: a machine learning strategy to predict binding sites based on residue neighborhood graphsSantana, Charles A ; Izidoro, Sandro C ; de Melo-Minardi, Raquel C ; Tyzack, Jonathan D ; Ribeiro, António J M ; Pires, Douglas E V ; Thornton, Janet M ; de A. Silveira, SabrinaNucleic acids research, 2022-07, Vol.50 (W1), p.W392-W397 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
12 |
Material Type: Artigo
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Reaction Decoder Tool (RDT): extracting features from chemical reactionsRahman, Syed Asad ; Torrance, Gilliean ; Baldacci, Lorenzo ; Martínez Cuesta, Sergio ; Fenninger, Franz ; Gopal, Nimish ; Choudhary, Saket ; May, John W ; Holliday, Gemma L ; Steinbeck, Christoph ; Thornton, Janet MBioinformatics, 2016-07, Vol.32 (13), p.2065-2066 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
13 |
Material Type: Artigo
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An automated protocol for modelling peptide substrates to proteasesOchoa, Rodrigo ; Magnitov, Mikhail ; Laskowski, Roman A ; Cossio, Pilar ; Thornton, Janet MBMC bioinformatics, 2020-12, Vol.21 (1), p.586-586, Article 586 [Periódico revisado por pares]England: BioMed Central LtdTexto completo disponível |
14 |
Material Type: Artigo
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Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project datasetde Beer, Tjaart A P ; Laskowski, Roman A ; Parks, Sarah L ; Sipos, Botond ; Goldman, Nick ; Thornton, Janet M Bromberg, YanaPLoS computational biology, 2013-12, Vol.9 (12), p.e1003382-e1003382 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
15 |
Material Type: Artigo
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DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegansTullet, Jennifer M A ; Araiz, Caroline ; Sanders, Matthew J ; Au, Catherine ; Benedetto, Alexandre ; Papatheodorou, Irene ; Clark, Emily ; Schmeisser, Kathrin ; Jones, Daniel ; Schuster, Eugene F ; Thornton, Janet M ; Gems, David Kim, Stuart K.PLoS genetics, 2014-02, Vol.10 (2), p.e1004109-e1004109 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
16 |
Material Type: Artigo
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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseasesMagraner-Pardo, Lorena ; Laskowski, Roman A ; Pons, Tirso ; Thornton, Janet MScientific reports, 2021-07, Vol.11 (1), p.14268-14268, Article 14268 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
17 |
Material Type: Artigo
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Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of ImmunityTyagi, Nidhi ; Farnell, Edward J ; Fitzsimmons, Colin M ; Ryan, Stephanie ; Tukahebwa, Edridah ; Maizels, Rick M ; Dunne, David W ; Thornton, Janet M ; Furnham, Nicholas Antia, RustomPLoS computational biology, 2015-10, Vol.11 (10), p.e1004546 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
18 |
Material Type: Artigo
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A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public dataIvanov, Dobril K ; Bostelmann, Gerrit ; Lan-Leung, Benoit ; Williams, Julie ; Partridge, Linda ; Escott-Price, Valentina ; Thornton, Janet M Li, XiaPloS one, 2020-10, Vol.15 (10), p.e0240824 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
19 |
Material Type: Artigo
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Exploring the evolution of novel enzyme functions within structurally defined protein superfamiliesFurnham, Nicholas ; Sillitoe, Ian ; Holliday, Gemma L ; Cuff, Alison L ; Laskowski, Roman A ; Orengo, Christine A ; Thornton, Janet M Ofran, YanayPLoS computational biology, 2012-03, Vol.8 (3), p.e1002403-e1002403 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
20 |
Material Type: Artigo
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Data-driven identification of ageing-related diseases from electronic health recordsKuan, Valerie ; Fraser, Helen C ; Hingorani, Melanie ; Denaxas, Spiros ; Gonzalez-Izquierdo, Arturo ; Direk, Kenan ; Nitsch, Dorothea ; Mathur, Rohini ; Parisinos, Constantinos A ; Lumbers, R Thomas ; Sofat, Reecha ; Wong, Ian C K ; Casas, Juan P ; Thornton, Janet M ; Hemingway, Harry ; Partridge, Linda ; Hingorani, Aroon DScientific reports, 2021-02, Vol.11 (1), p.2938-2938, Article 2938 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |