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Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites
Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites
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Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites

Ribeiro, António J M ; Holliday, Gemma L ; Furnham, Nicholas ; Tyzack, Jonathan D ; Ferris, Katherine ; Thornton, Janet M

Nucleic acids research, 2018-01, Vol.46 (D1), p.D618-D623 [Periódico revisado por pares]

England: Oxford University Press

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2
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes
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The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes

Furnham, Nicholas ; Holliday, Gemma L ; de Beer, Tjaart A P ; Jacobsen, Julius O B ; Pearson, William R ; Thornton, Janet M

Nucleic acids research, 2014-01, Vol.42 (Database issue), p.D485-D489 [Periódico revisado por pares]

England: Oxford University Press

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3
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
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New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

Sillitoe, Ian ; Cuff, Alison L ; Dessailly, Benoit H ; Dawson, Natalie L ; Furnham, Nicholas ; Lee, David ; Lees, Jonathan G ; Lewis, Tony E ; Studer, Romain A ; Rentzsch, Robert ; Yeats, Corin ; Thornton, Janet M ; Orengo, Christine A

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D490-D498 [Periódico revisado por pares]

England: Oxford University Press

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4
Using the drug-protein interactome to identify anti-ageing compounds for humans
Using the drug-protein interactome to identify anti-ageing compounds for humans
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Using the drug-protein interactome to identify anti-ageing compounds for humans

Fuentealba, Matías ; Dönertaş, Handan Melike ; Williams, Rhianna ; Labbadia, Johnathan ; Thornton, Janet M ; Partridge, Linda Iakoucheva, Lilia M.

PLoS computational biology, 2019-01, Vol.15 (1), p.e1006639-e1006639 [Periódico revisado por pares]

United States: Public Library of Science

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5
Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset
Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset
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Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset

de Beer, Tjaart A P ; Laskowski, Roman A ; Parks, Sarah L ; Sipos, Botond ; Goldman, Nick ; Thornton, Janet M Bromberg, Yana

PLoS computational biology, 2013-12, Vol.9 (12), p.e1003382-e1003382 [Periódico revisado por pares]

United States: Public Library of Science

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6
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans
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DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans

Tullet, Jennifer M A ; Araiz, Caroline ; Sanders, Matthew J ; Au, Catherine ; Benedetto, Alexandre ; Papatheodorou, Irene ; Clark, Emily ; Schmeisser, Kathrin ; Jones, Daniel ; Schuster, Eugene F ; Thornton, Janet M ; Gems, David Kim, Stuart K.

PLoS genetics, 2014-02, Vol.10 (2), p.e1004109-e1004109 [Periódico revisado por pares]

United States: Public Library of Science

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7
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing
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Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing

Papatheodorou, Irene ; Ziehm, Matthias ; Wieser, Daniela ; Alic, Nazif ; Partridge, Linda ; Thornton, Janet M Suh, Yousin

PloS one, 2012-12, Vol.7 (12), p.e50881-e50881 [Periódico revisado por pares]

United States: Public Library of Science

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8
Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network
Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network
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Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network

Ward, Jonathan J ; Thornton, Janet M Kishony, Roy

PLoS computational biology, 2007-10, Vol.3 (10), p.1993-2002 [Periódico revisado por pares]

United States: Public Library of Science

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9
The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data
The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data
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The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

Porter, Craig T. ; Bartlett, Gail J. ; Thornton, Janet M.

Nucleic acids research, 2004-01, Vol.32 (suppl-1), p.D129-D133 [Periódico revisado por pares]

England: Oxford University Press

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10
Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level
Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level
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Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level

Luscombe, N M ; Laskowski, R A ; Thornton, J M

Nucleic acids research, 2001-07, Vol.29 (13), p.2860-2874 [Periódico revisado por pares]

England: Oxford Publishing Limited (England)

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