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Material Type: Artigo
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VarSite: Disease variants and protein structureLaskowski, Roman A. ; Stephenson, James D. ; Sillitoe, Ian ; Orengo, Christine A. ; Thornton, Janet M.Protein science, 2020-01, Vol.29 (1), p.111-119 [Periódico revisado por pares]Hoboken, USA: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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Protein promiscuity and its implications for biotechnologyNobeli, Irene ; Favia, Angelo D ; Thornton, Janet MNature biotechnology, 2009-02, Vol.27 (2), p.157-167 [Periódico revisado por pares]New York, NY: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotationsStephenson, James D ; Laskowski, Roman A ; Nightingale, Andrew ; Hurles, Matthew E ; Thornton, Janet M Elofsson, ArneBioinformatics, 2019-11, Vol.35 (22), p.4854-4856 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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EC-BLAST: a tool to automatically search and compare enzyme reactionsRahman, Syed Asad ; Cuesta, Sergio Martinez ; Furnham, Nicholas ; Holliday, Gemma L ; Thornton, Janet MNature methods, 2014-02, Vol.11 (2), p.171-174 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Using the drug-protein interactome to identify anti-ageing compounds for humansFuentealba, Matías ; Dönertaş, Handan Melike ; Williams, Rhianna ; Labbadia, Johnathan ; Thornton, Janet M ; Partridge, Linda Iakoucheva, Lilia M.PLoS computational biology, 2019-01, Vol.15 (1), p.e1006639-e1006639 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public dataIvanov, Dobril K ; Bostelmann, Gerrit ; Lan-Leung, Benoit ; Williams, Julie ; Partridge, Linda ; Escott-Price, Valentina ; Thornton, Janet M Li, XiaPloS one, 2020-10, Vol.15 (10), p.e0240824 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Integrating population variation and protein structural analysis to improve clinical interpretation of missense variation: application to the WD40 domainLaskowski, Roman A ; Tyagi, Nidhi ; Johnson, Diana ; Joss, Shelagh ; Kinning, Esther ; McWilliam, Catherine ; Splitt, Miranda ; Thornton, Janet M ; Firth, Helen V ; Wright, Caroline FHuman molecular genetics, 2016-03, Vol.25 (5), p.927-935 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Characterising Complex Enzyme Reaction DataDönertaş, Handan Melike ; Martínez Cuesta, Sergio ; Rahman, Syed Asad ; Thornton, Janet M Srinivasan, NarayanaswamyPloS one, 2016-02, Vol.11 (2), p.e0147952-e0147952 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Missing in action: enzyme functional annotations in biological databasesFurnham, Nicholas ; Garavelli, John S ; Apweiler, Rolf ; Thornton, Janet MNature chemical biology, 2009-08, Vol.5 (8), p.521-525 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageingPapatheodorou, Irene ; Ziehm, Matthias ; Wieser, Daniela ; Alic, Nazif ; Partridge, Linda ; Thornton, Janet M Suh, YousinPloS one, 2012-12, Vol.7 (12), p.e50881-e50881 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |