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Material Type: Artigo
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Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanomaRibas, Antoni ; Lawrence, Donald ; Atkinson, Victoria ; Agarwal, Sachin ; Miller, Jr, Wilson H ; Carlino, Matteo S ; Fisher, Rosalie ; Long, Georgina V ; Hodi, F Stephen ; Tsoi, Jennifer ; Grasso, Catherine S ; Mookerjee, Bijoyesh ; Zhao, Qing ; Ghori, Razi ; Moreno, Blanca Homet ; Ibrahim, Nageatte ; Hamid, OmidNature medicine, 2019-06, Vol.25 (6), p.936-940 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanomaAscierto, Paolo Antonio ; Ferrucci, Pier Francesco ; Fisher, Rosalie ; Del Vecchio, Michele ; Atkinson, Victoria ; Schmidt, Henrik ; Schachter, Jacob ; Queirolo, Paola ; Long, Georgina V ; Di Giacomo, Anna Maria ; Svane, Inge Marie ; Lotem, Michal ; Bar-Sela, Gil ; Couture, Felix ; Mookerjee, Bijoyesh ; Ghori, Razi ; Ibrahim, Nageatte ; Moreno, Blanca Homet ; Ribas, AntoniNature medicine, 2019-06, Vol.25 (6), p.941-946 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanomaFerrucci, Pier Francesco ; Di Giacomo, Anna Maria ; Del Vecchio, Michele ; Atkinson, Victoria ; Schmidt, Henrik ; Schachter, Jacob ; Queirolo, Paola ; Long, Georgina V ; Stephens, Rosalie ; Svane, Inge Marie ; Lotem, Michal ; Abu-Amna, Mahmoud ; Gasal, Eduard ; Ghori, Razi ; Diede, Scott J ; Croydon, Elizabeth S ; Ribas, Antoni ; Ascierto, Paolo AntonioJournal for immunotherapy of cancer, 2020-12, Vol.8 (2), p.e001806 [Periódico revisado por pares]England: BMJ Publishing Group LtdTexto completo disponível |
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Material Type: Artigo
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Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 StudyMarabelle, Aurelien ; Le, Dung T ; Ascierto, Paolo A ; Di Giacomo, Anna Maria ; De Jesus-Acosta, Ana ; Delord, Jean-Pierre ; Geva, Ravit ; Gottfried, Maya ; Penel, Nicolas ; Hansen, Aaron R ; Piha-Paul, Sarina A ; Doi, Toshihiko ; Gao, Bo ; Chung, Hyun Cheol ; Lopez-Martin, Jose ; Bang, Yung-Jue ; Frommer, Ronnie Shapira ; Shah, Manisha ; Ghori, Razi ; Joe, Andrew K ; Pruitt, Scott K ; Diaz, Jr, Luis AJournal of clinical oncology, 2020-01, Vol.38 (1), p.1-10 [Periódico revisado por pares]United States: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Pembrolizumab combined with carfilzomib and low‐dose dexamethasone for relapsed or refractory multiple myeloma: Cohort 2 of the phase I KEYNOTE‐023 studyMoreau, Philippe ; Ghori, Razi ; Farooqui, Mohammed ; Marinello, Patricia ; San Miguel, JesusBritish journal of haematology, 2021-07, Vol.194 (1), p.e48-e51 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Pembrolizumab combined with lenalidomide and low‐dose dexamethasone for relapsed or refractory multiple myeloma: phase I KEYNOTE‐023 studyMateos, Maria‐Victoria ; Orlowski, Robert Z. ; Ocio, Enrique M. ; Rodríguez‐Otero, Paula ; Reece, Donna ; Moreau, Philippe ; Munshi, Nikhil ; Avigan, David E. ; Siegel, David S. ; Ghori, Razi ; Farooqui, Mohammed Z. H. ; Marinello, Patricia ; San-Miguel, JesusBritish journal of haematology, 2019-09, Vol.186 (5), p.e117-e121 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Pembrolizumab plus lenalidomide and dexamethasone for patients with treatment-naive multiple myeloma (KEYNOTE-185): a randomised, open-label, phase 3 trialUsmani, Saad Zafar ; Schjesvold, Fredrik ; Oriol, Albert ; Karlin, Lionel ; Cavo, Michele ; LeBlanc, Richard ; Takezako, Naoki ; Lim, Andrew Boon Ming ; Suzuki, Kenshi ; Kosugi, Hiroshi ; Grigoriadis, George ; Avivi, Irit ; Facon, Thierry ; Jagannath, Sundar ; Lonial, Sagar ; Ghori, Razi Uddin ; Farooqui, Mohammed Z H ; Marinello, Patricia ; Lim, Andrew ; Grigoriadis, George ; Walker, Trish ; Nicol, Andrew ; LeBlanc, Richard ; Reece, Donna ; Elemary, Mohamed ; Karlin, Lionel ; Attal, Michel ; Engelhardt, Monika ; Mackensen, Andreas ; Quinn, John ; Avivi, Irit ; Cohen, Amos ; Magen-Nativ, Hila ; Cavo, Michele ; Larocca, Alessandra ; Takezako, Naoki ; Suzuki, Kenshi ; Kosugi, Hiroshi ; Matsumoto, Morio ; Iida, Shinsuke ; Ishikawa, Takayuki ; Kondo, Yukio ; Sunami, Kazutaka ; Ando, Kiyoshi ; Teshima, Takanori ; Chou, Takaaki ; Iwasaki, Hiromi ; Miki, Hirokazu ; Matsumura, Itaru ; Onishi, Yasushi ; Izutsu, Koji ; Kizaki, Masahiro ; George, Anupkumar ; Blacklock, Hillary ; Schjesvold, Fredrik ; Waage, Anders ; Nikitin, Evgeniy ; Chagorova, Tatiana ; McDonald, Andrew ; Patel, Moosa ; Oriol Rocafiguera, Albert ; San Miguel Izquierdo, Jesus ; Mateos, Maria ; Streetly, Matthew ; Forsyth, Peter ; Jackson, Graham ; Jenkins, Stephen ; Rifkin, Robert ; Yimer, Habte ; McCroskey, Robert ; Martincic, Danko ; Tarantolo, Stefano ; Larson, Sarah ; Faroun, Yacoub ; Vaughn, Jennifer ; Saylors, Gene ; Fung, Henry ; Stevens, Don ; Coleman, Morton ; Costa, Dennis ; Cross, Scott ; Fanning, Suzanne ; Berges, Daniel Farray ; Harris, Thomas ; Zackon, Ira ; Atanackovic, Djordje ; Oliff, Ira ; Lee, Wes ; Bensinger, William ; Lutzky, Jose ; Baron, Ari ; Kirschner, Eli ; Bharany, Neeraj ; Overton, Lindsay ; Mannem, Siva ; Harroff, Allyson ; Jain, Sharad ; Roque, Tammy ; Yasencha, Christopher K ; Houck, WilliamThe Lancet. Haematology, 2019-09, Vol.6 (9), p.e448-e458 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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KEYNOTE-022: Pembrolizumab with trametinib in patients with BRAF wild-type melanoma or advanced solid tumours irrespective of BRAF mutationMaio, Michele ; Carlino, Matteo S. ; Joshua, Anthony M. ; McWhirter, Elaine ; Ribas, Antoni ; Ascierto, Paolo A. ; Miller, Wilson H. ; Butler, Marcus O. ; Ferrucci, Pier Francesco ; Zielinski, Robert R. ; Del Vecchio, Michele ; Gasal, Eduard ; Ghori, Razi ; Diede, Scott J. ; Croydon, Elizabeth ; Hamid, OmidEuropean journal of cancer (1990), 2022-01, Vol.160, p.1-11 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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First-in-Human Study of the Reversible BTK Inhibitor Nemtabrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia and B-Cell Non-Hodgkin LymphomaWoyach, Jennifer A ; Stephens, Deborah M ; Flinn, Ian W ; Bhat, Seema A ; Savage, Ronald E ; Chai, Feng ; Eathiraj, Sudharshan ; Reiff, Sean D ; Muhowski, Elizabeth M ; Granlund, Lindsey ; Szuszkiewicz, Lyndsey ; Wang, Wayne ; Schwartz, Brian ; Ghori, Razi ; Farooqui, Mohammed Z H ; Byrd, John CCancer discovery, 2024-01, Vol.14 (1), p.66-75United StatesTexto completo disponível |
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Material Type: Artigo
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Pembrolizumab plus lenalidomide and dexamethasone in treatment-naive multiple myeloma (KEYNOTE-185): subgroup analysis in Japanese patientsTakezako, Naoki ; Kosugi, Hiroshi ; Matsumoto, Morio ; Iida, Shinsuke ; Ishikawa, Takayuki ; Kondo, Yukio ; Ando, Kiyoshi ; Miki, Hirokazu ; Matsumura, Itaru ; Sunami, Kazutaka ; Teshima, Takanori ; Iwasaki, Hiromi ; Onishi, Yasushi ; Kizaki, Masahiro ; Izutsu, Koji ; Maruyama, Dai ; Tobinai, Kensei ; Ghori, Razi ; Farooqui, Mohammed ; Liao, Jason ; Marinello, Patricia ; Matsuda, Kenji ; Koh, Yasuhiro ; Shimamoto, Takashi ; Suzuki, KenshiInternational journal of hematology, 2020-11, Vol.112 (5), p.640-649 [Periódico revisado por pares]Singapore: Springer SingaporeTexto completo disponível |