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1
Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression
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Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression

Chen, Xi-Lin ; Dodd, Geraldine ; Thomas, Suzanne ; Zhang, Xiaolan ; Wasserman, Martin A ; Rovin, Brad H ; Kunsch, Charles

American journal of physiology. Heart and circulatory physiology, 2006-05, Vol.290 (5), p.H1862-H1870 [Periódico revisado por pares]

United States

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2
Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
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Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells

MARUI, N ; OFFERMANN, M. K ; SWERLICK, R ; KUNSCH, C ; ROSEN, C. A ; MUSHTAQ AHMAD ; ALEXANDER, R. W ; MEDFORD, R. M

The Journal of clinical investigation, 1993-10, Vol.92 (4), p.1866-1874 [Periódico revisado por pares]

Ann Arbor, MI: American Society for Clinical Investigation

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3
Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism
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Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism

Chen, Xi-Lin ; Varner, Signe E ; Rao, Anjali S ; Grey, Janice Y ; Thomas, Suzanne ; Cook, Christopher K ; Wasserman, Martin A ; Medford, Russell M ; Jaiswal, Anil K ; Kunsch, Charles

The Journal of biological chemistry, 2003-01, Vol.278 (2), p.703-711 [Periódico revisado por pares]

United States

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4
Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family
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Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family

Oettgen, Peter ; Alani, Rhoda M. ; Barcinski, Marcello A. ; Brown, Lawrence ; Akbarali, Yasmin ; Boltax, Jay ; Kunsch, Charles ; Munger, Karl ; Libermann, Towia A.

Molecular and Cellular Biology, 1997-08, Vol.17 (8), p.4419-4433 [Periódico revisado por pares]

United States: American Society for Microbiology

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5
Selective Inhibition of Endothelial and Monocyte Redox-Sensitive Genes by AGI-1067: A Novel Antioxidant and Anti-Inflammatory Agent
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Selective Inhibition of Endothelial and Monocyte Redox-Sensitive Genes by AGI-1067: A Novel Antioxidant and Anti-Inflammatory Agent

Kunsch, Charles ; Luchoomun, Jayraz ; Grey, Janice Y ; Olliff, Lynda K ; Saint, Leigh B ; Arrendale, Richard F ; Wasserman, Martin A ; Saxena, Uday ; Medford, Russell M

The Journal of pharmacology and experimental therapeutics, 2004-03, Vol.308 (3), p.820-829 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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6
Sphingosine kinase-1 mediates TNF-alpha-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow
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Sphingosine kinase-1 mediates TNF-alpha-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow

Chen, Xi-Lin ; Grey, Janice Y ; Thomas, Suzanne ; Qiu, Fei-Hua ; Medford, Russell M ; Wasserman, Martin A ; Kunsch, Charles

American journal of physiology. Heart and circulatory physiology, 2004-10, Vol.287 (4), p.H1452-H1458 [Periódico revisado por pares]

United States

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7
Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases
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Discovery of Novel Phenolic Antioxidants as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Meng, Charles Q ; Somers, Patricia K ; Hoong, Lee K ; Zheng, X. Sharon ; Ye, Zhihong ; Worsencroft, Kimberly J ; Simpson, Jacob E ; Hotema, Martha R ; Weingarten, M. David ; MacDonald, Mathew L ; Hill, Russell R ; Marino, Elaine M ; Suen, Ki-Ling ; Luchoomun, Jayraz ; Kunsch, Charles ; Landers, Laura K ; Stefanopoulos, Dimitria ; Howard, Randy B ; Sundell, Cynthia L ; Saxena, Uday ; Wasserman, Martin A ; Sikorski, James A

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6420-6432 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
Carboxylated, Heteroaryl-Substituted Chalcones as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases
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Carboxylated, Heteroaryl-Substituted Chalcones as Inhibitors of Vascular Cell Adhesion Molecule-1 Expression for Use in Chronic Inflammatory Diseases

Meng, Charles Q ; Ni, Liming ; Worsencroft, Kimberly J ; Ye, Zhihong ; Weingarten, M. David ; Simpson, Jacob E ; Skudlarek, Jason W ; Marino, Elaine M ; Suen, Ki-Ling ; Kunsch, Charles ; Souder, Amy ; Howard, Randy B ; Sundell, Cynthia L ; Wasserman, Martin A ; Sikorski, James A

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1304-1315 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression
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AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression

Kunsch, Charles ; Luchoomun, Jayraz ; Chen, Xi-Lin ; Dodd, Geraldine L ; Karu, Kanika S ; Meng, Charles Q ; Marino, Elaine M ; Olliff, Lyn K ; Piper, J Daniel ; Qiu, Fei-Hua ; Sikorski, James A ; Somers, Patricia K ; Suen, Ki-Ling ; Thomas, Suzanne ; Whalen, Anne M ; Wasserman, Martin A ; Sundell, Cynthia L

The Journal of pharmacology and experimental therapeutics, 2005-05, Vol.313 (2), p.492-501 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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10
A sense phosphorothioate oligonucleotide directed to the initiation codon of transcription factor NF-kappa B p65 causes sequence-specific immune stimulation
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A sense phosphorothioate oligonucleotide directed to the initiation codon of transcription factor NF-kappa B p65 causes sequence-specific immune stimulation

McIntyre, K W ; Lombard-Gillooly, K ; Perez, J R ; Kunsch, C ; Sarmiento, U M ; Larigan, J D ; Landreth, K T ; Narayanan, R

Antisense research and development, 1993, Vol.3 (4), p.309-322

United States

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