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Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites
Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites
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Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites

Bowman, Gregory R ; Geissler, Phillip L

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (29), p.11681-11686 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Discovery of multiple hidden allosteric sites by combining Markov state models and experiments
Discovery of multiple hidden allosteric sites by combining Markov state models and experiments
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Discovery of multiple hidden allosteric sites by combining Markov state models and experiments

Bowman, Gregory R. ; Bolin, Eric R. ; Hart, Kathryn M. ; Maguire, Brendan C. ; Marqusee, Susan

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2734-2739 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
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Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Eng, Christina H. ; Wang, Zuncai ; Tkach, Diane ; Toral-Barza, Lourdes ; Ugwonali, Savuth ; Liu, Shanming ; Fitzgerald, Stephanie L. ; George, Elizabeth ; Frias, Elizabeth ; Cochran, Nadire ; De Jesus, Rowena ; McAllister, Gregory ; Hoffman, Gregory R. ; Bray, Kevin ; Lemon, LuAnna ; Lucas, Judy ; Fantin, Valeria R. ; Abraham, Robert T. ; Murphy, Leon O. ; Nyfeler, Beat

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (1), p.182-187 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers

Hoffman, Gregory R. ; Rahal, Rami ; Buxton, Frank ; Xiang, Kay ; McAllister, Gregory ; Frias, Elizabeth ; Bagdasarian, Linda ; Huber, Janina ; Lindeman, Alicia ; Chen, Dongshu ; Romero, Rodrigo ; Ramadan, Nadire ; Phadke, Tanushree ; Haas, Kristy ; Jaskelioff, Mariela ; Wilson, Boris G. ; Meyer, Matthew J. ; Saenz-Vash, Veronica ; Zhai, Huili ; Myer, Vic E. ; Porter, Jeffrey A. ; Keen, Nicholas ; McLaughlin, Margaret E. ; Mickanin, Craig ; Roberts, Charles W. M. ; Stegmeier, Frank ; Jagani, Zainab

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.3128-3133 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
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Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

Ghosn, Eliver Eid Bou ; Cassado, Alexandra A ; Govoni, Gregory R ; Fukuhara, Takeshi ; Yang, Yang ; Monack, Denise M ; Bortoluci, Karina R ; Almeida, Sandro R ; Herzenberg, Leonard A ; Herzenberg, Leonore A

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2568-2573 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Protein folded states are kinetic hubs
Protein folded states are kinetic hubs
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Protein folded states are kinetic hubs

Bowman, Gregory R ; Pande, Vijay S

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10890-10895 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Noninvasive imaging of immune responses
Noninvasive imaging of immune responses
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Noninvasive imaging of immune responses

Rashidian, Mohammad ; Keliher, Edmund J. ; Bilate, Angelina M. ; Duarte, Joao N. ; Wojtkiewicz, Gregory R. ; Jacobsen, Johanne Tracey ; Cragnolini, Juanjo ; Swee, Lee Kim ; Victora, Gabriel D. ; Weissleder, Ralph ; Ploegh, Hidde L.

Proceedings of the National Academy of Sciences - PNAS, 2015-05, Vol.112 (19), p.6146-6151 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
The gut microbiome regulates host glucose homeostasis via peripheral serotonin
The gut microbiome regulates host glucose homeostasis via peripheral serotonin
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The gut microbiome regulates host glucose homeostasis via peripheral serotonin

Martin, Alyce M. ; Yabut, Julian M. ; Choo, Jocelyn M. ; Page, Amanda J. ; Sun, Emily W. ; Jessup, Claire F. ; Wesselingh, Steve L. ; Khan, Waliul I. ; Rogers, Geraint B. ; Steinberg, Gregory R. ; Keating, Damien J.

Proceedings of the National Academy of Sciences - PNAS, 2019-10, Vol.116 (40), p.19802-19804 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy
Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy
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Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

Potting, Christoph ; Crochemore, Christophe ; Moretti, Francesca ; Nigsch, Florian ; Schmidt, Isabel ; Manneville, Carole ; Carbone, Walter ; Knehr, Judith ; DeJesus, Rowena ; Lindeman, Alicia ; Maher, Rob ; Russ, Carsten ; McAllister, Gregory ; Reece-Hoyes, John S. ; Hoffman, Gregory R. ; Roma, Guglielmo ; Müller, Matthias ; Sailer, Andreas W. ; Helliwell, Stephen B.

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (2), p.E180-E189 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Parallel adaptive evolution of geographically distant herring populations on both sides of the North Atlantic Ocean
Parallel adaptive evolution of geographically distant herring populations on both sides of the North Atlantic Ocean
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Parallel adaptive evolution of geographically distant herring populations on both sides of the North Atlantic Ocean

Lamichhaney, Sangeet ; Fuentes-Pardo, Angela P. ; Rafati, Nima ; Ryman, Nils ; McCracken, Gregory R. ; Bourne, Christina ; Singh, Rabindra ; Ruzzante, Daniel E. ; Andersson, Leif

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (17), p.E3452-E3461 [Periódico revisado por pares]

United States: National Academy of Sciences

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