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1
Mesoionic pyrido[1,2-a]pyrimidinones: A novel class of insecticides inhibiting nicotinic acetylcholine receptors
Mesoionic pyrido[1,2-a]pyrimidinones: A novel class of insecticides inhibiting nicotinic acetylcholine receptors
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Mesoionic pyrido[1,2-a]pyrimidinones: A novel class of insecticides inhibiting nicotinic acetylcholine receptors

Zhang, Wenming ; Holyoke, Caleb W. ; Barry, James ; Leighty, Robert M. ; Cordova, Daniel ; Vincent, Daniel R. ; Hughes, Kenneth A. ; Tong, My-Hanh T. ; McCann, Stephen F. ; Xu, Ming ; Briddell, Twyla A. ; Pahutski, Thomas F. ; Lahm, George P.

Bioorganic & medicinal chemistry letters, 2016-11, Vol.26 (22), p.5444-5449 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors
Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors
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Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors

Shen, Hong C. ; Ding, Fa-Xiang ; Wang, Siyi ; Xu, Suoyu ; Chen, Hsuan-shen ; Tong, Xinchun ; Tong, Vincent ; Mitra, Kaushik ; Kumar, Sanjeev ; Zhang, Xiaoping ; Chen, Yuli ; Zhou, Gaochao ; Pai, Lee-Yuh ; Alonso-Galicia, Magdalena ; Chen, Xiaoli ; Zhang, Bei ; Tata, James R. ; Berger, Joel P. ; Colletti, Steven L.

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3398-3404 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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3
Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase
Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase
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Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase

Camerino, Eugene ; Wong, Dawn M. ; Tong, Fan ; Körber, Florian ; Gross, Aaron D. ; Islam, Rafique ; Viayna, Elisabet ; Mutunga, James M. ; Li, Jianyong ; Totrov, Maxim M. ; Bloomquist, Jeffrey R. ; Carlier, Paul R.

Bioorganic & medicinal chemistry letters, 2015-10, Vol.25 (20), p.4405-4411 [Periódico revisado por pares]

England: Elsevier Ltd

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4
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core
Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core
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Discovery of novel, potent, selective, and orally active human glucagon receptor antagonists containing a pyrazole core

Shen, Dong-Ming ; Brady, Edward J. ; Candelore, Mari R. ; Dallas-Yang, Qing ; Ding, Victor D.-H. ; Feeney, William P. ; Jiang, Guoquiang ; McCann, Margaret E. ; Mock, Steve ; Qureshi, Sajjad A. ; Saperstein, Richard ; Shen, Xiaolan ; Tong, Xinchun ; Tota, Laurie M. ; Wright, Michael J. ; Yang, Xiaodong ; Zheng, Song ; Chapman, Kevin T. ; Zhang, Bei B. ; Tata, James R. ; Parmee, Emma R.

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.76-81 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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5
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2
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Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Corbett, Jeffrey W. ; Freeman-Cook, Kevin D. ; Elliott, Richard ; Vajdos, Felix ; Rajamohan, Francis ; Kohls, Darcy ; Marr, Eric ; Zhang, Hailong ; Tong, Liang ; Tu, Meihua ; Murdande, Sharad ; Doran, Shawn D. ; Houser, Janet A. ; Song, Wei ; Jones, Christopher J. ; Coffey, Steven B. ; Buzon, Leanne ; Minich, Martha L. ; Dirico, Kenneth J. ; Tapley, Susan ; Kirk McPherson, R. ; Sugarman, Eliot ; James Harwood, H. ; Esler, William

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2383-2388 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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6
Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus
Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus
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Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus

Xu, Jiayi ; Lin, Songnian ; Myers, Robert W. ; Addona, George ; Berger, Joel P. ; Campbell, Brian ; Chen, Hsuan-shen ; Chen, Zhesheng ; Eiermann, George J. ; Elowe, Nadine H. ; Farrer, Brian T. ; Feng, Wen ; Fu, Qinghong ; Kats-Kagan, Roman ; Kavana, Michael ; Malkani, Sunita ; McMasters, Daniel R. ; Mitra, Kaushik ; Pachanski, Michele J. ; Tong, Xinchun ; Trujillo, Maria E. ; Xu, Libo ; Zhang, Bei ; Zhang, Fengqi ; Zhang, Rui ; Parmee, Emma R.

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (9), p.2069-2073 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide1
Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide1
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Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide1

Zhang, Wenming ; Holyoke, Caleb W. ; Pahutski, Thomas F. ; Lahm, George P. ; Barry, James D. ; Cordova, Daniel ; Leighty, Robert M. ; Singh, Vineet ; Vicent, Daniel R. ; Tong, My-Hanh T. ; Hughes, Kenneth A. ; McCann, Stephen F. ; Henry, Yewande T. ; Xu, Ming ; Briddell, Twyla A.

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.16-20 [Periódico revisado por pares]

Elsevier Ltd

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8
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors
Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors
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Discovery of 3,3-disubstituted piperidine-derived trisubstituted ureas as highly potent soluble epoxide hydrolase inhibitors

Shen, Hong C. ; Ding, Fa-Xiang ; Deng, Qiaolin ; Xu, Suoyu ; Chen, Hsuan-shen ; Tong, Xinchun ; Tong, Vincent ; Zhang, Xiaoping ; Chen, Yuli ; Zhou, Gaochao ; Pai, Lee-Yuh ; Alonso-Galicia, Magdalena ; Zhang, Bei ; Roy, Sophie ; Tata, James R. ; Berger, Joel P. ; Colletti, Steven L.

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5314-5320 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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9
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
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Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

Martín-Martín, María Luz ; Bartolomé-Nebreda, José Manuel ; Conde-Ceide, Susana ; Alonso de Diego, Sergio A. ; López, Silvia ; Martínez-Viturro, Carlos M. ; Tong, Han Min ; Lavreysen, Hilde ; Macdonald, Gregor J. ; Steckler, Thomas ; Mackie, Claire ; Bridges, Thomas M. ; Daniels, J. Scott ; Niswender, Colleen M. ; Noetzel, Meredith J. ; Jones, Carrie K. ; Conn, P. Jeffrey ; Lindsley, Craig W. ; Stauffer, Shaun R.

Bioorganic & medicinal chemistry letters, 2015-03, Vol.25 (6), p.1310-1317 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1
Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1
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Mesoionic pyrido[1,2- a ]pyrimidinones: Discovery of triflumezopyrim as a potent hopper insecticide 1

Zhang, Wenming ; Holyoke, Caleb W. ; Pahutski, Thomas F. ; Lahm, George P. ; Barry, James D. ; Cordova, Daniel ; Leighty, Robert M. ; Singh, Vineet ; Vicent, Daniel R. ; Tong, My-Hanh T. ; Hughes, Kenneth A. ; McCann, Stephen F. ; Henry, Yewande T. ; Xu, Ming ; Briddell, Twyla A.

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.16-20 [Periódico revisado por pares]

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