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Species Independence in Brain Tissue Binding Using Brain Homogenates
Species Independence in Brain Tissue Binding Using Brain Homogenates
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Species Independence in Brain Tissue Binding Using Brain Homogenates

LI DI ; UMLAND, John P ; CHANG, George ; YOUPING HUANG ; ZHEN LIN ; SCOTT, Dennis O ; TROUTMAN, Matthew D ; LISTON, Theodore E

Drug metabolism and disposition, 2011-07, Vol.39 (7), p.1270-1277 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations
In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations
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In Vitro Metabolic Activation of Lumiracoxib in Rat and Human Liver Preparations

Li, Ying ; Slatter, J Greg ; Zhang, Zhoupeng ; Li, Yan ; Doss, George A ; Braun, Matthew P ; Stearns, Ralph A ; Dean, Dennis C ; Baillie, Thomas A ; Tang, Wei

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.469-473 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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EVIDENCE FOR THE BIOACTIVATION OF ZOMEPIRAC AND TOLMETIN BY AN OXIDATIVE PATHWAY: IDENTIFICATION OF GLUTATHIONE ADDUCTS IN VITRO IN HUMAN LIVER MICROSOMES AND IN VIVO IN RATS
EVIDENCE FOR THE BIOACTIVATION OF ZOMEPIRAC AND TOLMETIN BY AN OXIDATIVE PATHWAY: IDENTIFICATION OF GLUTATHIONE ADDUCTS IN VITRO IN HUMAN LIVER MICROSOMES AND IN VIVO IN RATS
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EVIDENCE FOR THE BIOACTIVATION OF ZOMEPIRAC AND TOLMETIN BY AN OXIDATIVE PATHWAY: IDENTIFICATION OF GLUTATHIONE ADDUCTS IN VITRO IN HUMAN LIVER MICROSOMES AND IN VIVO IN RATS

Chen, Qing ; Doss, George A ; Tung, Elaine C ; Liu, Wensheng ; Tang, Yui S ; Braun, Matthew P ; Didolkar, Varsha ; Strauss, John R ; Wang, Regina W ; Stearns, Ralph A ; Evans, David C ; Baillie, Thomas A ; Tang, Wei

Drug metabolism and disposition, 2006-01, Vol.34 (1), p.145-151 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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4
HUMAN CYTOCHROME P450 INDUCTION AND INHIBITION POTENTIAL OF CLEVIDIPINE AND ITS PRIMARY METABOLITE H152/81
HUMAN CYTOCHROME P450 INDUCTION AND INHIBITION POTENTIAL OF CLEVIDIPINE AND ITS PRIMARY METABOLITE H152/81
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HUMAN CYTOCHROME P450 INDUCTION AND INHIBITION POTENTIAL OF CLEVIDIPINE AND ITS PRIMARY METABOLITE H152/81

ZHANG, J. George ; DEHAL, Shangara S ; HO, Thuy ; JOHNSON, Jennifer ; CHANDLER, Catherine ; BLANCHARD, Andrew P ; CLARK, Robert J ; CRESPI, Charles L ; STRESSER, David M ; WONG, James

Drug metabolism and disposition, 2006-05, Vol.34 (5), p.734-737 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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5
Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites
Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites
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Studies on Cytochrome P-450-Mediated Bioactivation of Diclofenac in Rats and in Human Hepatocytes: Identification of Glutathione Conjugated Metabolites

WEI TANG ; STEARNS, R. A ; STRAUSS, J. R ; KWEI, G. Y ; RUSHMORE, T. H ; CHIU, S.-H. L ; BAILLIE, T. A ; BANDIERA, S. M ; YONG ZHANG ; RAAB, C ; BRAUN, M. P ; DEAN, D. C ; JIANMEI PANG ; LEUNG, K. H ; DOSS, G. A

Drug metabolism and disposition, 1999-03, Vol.27 (3), p.365-372 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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6
THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS
THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS
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THE METABOLIC DISPOSITION OF APREPITANT, A SUBSTANCE P RECEPTOR ANTAGONIST, IN RATS AND DOGS

HUSKEY, Su-Er W ; DEAN, Brian J ; STRAUSS, John R ; CUNNINGHAM, Paul K ; FEENEY, William P ; FRANKLIN, Ronald B ; BAILLIE, Thomas A ; CHIU, Shuet-Hing L ; DOSS, George A ; ZHEN WANG ; HOP, Cornelis E. C. A ; ANARI, Reza ; FINKE, Paul E ; ROBICHAUD, Albert J ; MINGHUA ZHANG ; WANG, Bonnie

Drug metabolism and disposition, 2004-02, Vol.32 (2), p.246-258 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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7
Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans
Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans
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Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans

POON, Grace K ; QING CHEN ; BAILLIE, Thomas A ; WEI TANG ; TEFFERA, Yohannes ; NGUI, Jason S ; GRIFFIN, Patrick R ; BRAUN, Mathew P ; DOSS, George A ; FREEDEN, Christopher ; STEARNS, Ralph A ; EVANS, David C

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1608-1613 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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8
Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys
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Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys

TAN, Eugene Y ; HARTMANN, Georgy ; WEI TANG ; KUMAR, Sanjeev ; QING CHEN ; PEREIRA, Antonio ; BRADLEY, Scott ; DOSS, George ; ZHANG, Andy Shiqiang ; HO, Jonathan Z ; BRAUN, Matthew P ; DEAN, Dennis C

Drug metabolism and disposition, 2010-03, Vol.38 (3), p.459-473 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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9
INHIBITION AND RECOVERY OF RAT HEPATIC GLUTATHIONE S-TRANSFERASE ZETA AND ALTERATION OF TYROSINE METABOLISM FOLLOWING DICHLOROACETATE EXPOSURE AND WITHDRAWAL
INHIBITION AND RECOVERY OF RAT HEPATIC GLUTATHIONE S-TRANSFERASE ZETA AND ALTERATION OF TYROSINE METABOLISM FOLLOWING DICHLOROACETATE EXPOSURE AND WITHDRAWAL
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INHIBITION AND RECOVERY OF RAT HEPATIC GLUTATHIONE S-TRANSFERASE ZETA AND ALTERATION OF TYROSINE METABOLISM FOLLOWING DICHLOROACETATE EXPOSURE AND WITHDRAWAL

Guo, Xu ; Dixit, Vaishali ; Liu, Huiping ; Shroads, Albert L ; Henderson, George N ; James, Margaret O ; Stacpoole, Peter W

Drug metabolism and disposition, 2006-01, Vol.34 (1), p.36-42 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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10
The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs
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The Absorption, Distribution, Metabolism and Excretion of Rofecoxib, a Potent and Selective Cyclooxygenase-2 Inhibitor, in Rats and Dogs

HALPIN, Rita A ; GEER, Leslie A ; ZHANG, Kanyin E ; MARKS, Tina M ; DEAN, Dennis C ; JONES, Allen N ; MELILLO, David ; DOSS, George ; VYAS, Kamlesh P

Drug metabolism and disposition, 2000-10, Vol.28 (10), p.1244-1254 [Periódico revisado por pares]

Bethesda, MD: American Society for Pharmacology and Experimental Therapeutics

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