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Material Type: Artigo
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Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination TherapyLEWIS PHILLIPS, Gail D ; FIELDS, Carter T ; DIERAS, Veronique ; CRIVELLARI, Diana ; LIANG FANG ; GUARDINO, Ellie ; OLSEN, Steven R ; CROCKER, Lisa M ; SLIWKOWSKI, Mark X ; GUANGMIN LI ; DOWBENKO, Donald ; SCHAEFER, Gabriele ; MILLER, Kathy ; ANDRE, Fabrice ; BURRIS, Howard A ; ALBAIN, Kathy S ; HARBECK, NadiaClinical cancer research, 2014-01, Vol.20 (2), p.456-468 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast CancerJUNUTULA, Jagath R ; FLAGELLA, Kelly M ; MAI, Elaine ; LEWIS PHILLIPS, Gail D ; HIRARAGI, Hajime ; FUJI, Reina N ; TIBBITTS, Jay ; VANDLEN, Richard ; SPENCER, Susan D ; SCHELLER, Richard H ; POLAKIS, Paul ; SLIWKOWSKI, Mark X ; GRAHAM, Richard A ; PARSONS, Kathryn L ; HA, Edward ; RAAB, Helga ; BHAKTA, Sunil ; NGUYEN, Trung ; DUGGER, Debra L ; GUANGMIN LIClinical cancer research, 2010-10, Vol.16 (19), p.4769-4778 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Navitoclax (ABT‐263) and bendamustine ± rituximab induce enhanced killing of non‐Hodgkin's lymphoma tumours in vivoAckler, S ; Mitten, MJ ; Chen, J ; Clarin, J ; Foster, K ; Jin, S ; Phillips, DC ; Schlessinger, S ; Wang, B ; Leverson, JD ; Boghaert, ERBritish journal of pharmacology, 2012-10, Vol.167 (4), p.881-891 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Developmental Programming: Deficits in Reproductive Hormone Dynamics and Ovulatory Outcomes in Prenatal, Testosterone-Treated SheepVeiga-Lopez, A ; Ye, W ; Phillips, D.J ; Herkimer, C ; Knight, P.G ; Padmanabhan, VBiology of reproduction, 2008-04, Vol.78 (4), p.636-647 [Periódico revisado por pares]Madison, WI: Society for the Study of Reproduction, IncTexto completo disponível |
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Material Type: Artigo
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Mechanistic pharmacokinetic/pharmacodynamic modeling of in vivo tumor uptake, catabolism, and tumor response of trastuzumab maytansinoid conjugatesWada, Russ ; Erickson, Hans K. ; Lewis Phillips, Gail D. ; Provenzano, Carmela A. ; Leipold, Douglas D. ; Mai, Elaine ; Johnson, Holly ; Tibbitts, JayCancer chemotherapy and pharmacology, 2014-11, Vol.74 (5), p.969-980 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Understanding the genotoxicity of tamoxifen?PHILLIPS, David HCarcinogenesis (New York), 2001-06, Vol.22 (6), p.839-849 [Periódico revisado por pares]Oxford: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Development of Ruthenium Antitumor Drugs that Overcome Multidrug Resistance MechanismsVock, Carsten A ; Ang, Wee Han ; Scolaro, Claudine ; Phillips, Andrew D ; Lagopoulos, Lucienne ; Juillerat-Jeanneret, Lucienne ; Sava, Gianni ; Scopelliti, Rosario ; Dyson, Paul JJournal of medicinal chemistry, 2007-05, Vol.50 (9), p.2166-2175 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Platelet glycoprotein IIb/IIIa antagonists : What are the relevant issues concerning their pharmacology and clinical use?SCARBOROUGH, R. M ; KLEIMAN, N. S ; PHILLIPS, D. RCirculation (New York, N.Y.), 1999-07, Vol.100 (4), p.437-444 [Periódico revisado por pares]Hagerstown, MD: Lippincott Williams & WilkinsTexto completo disponível |
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Material Type: Artigo
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Clinical Pharmacology of EptifibatidePhillips, David R ; Scarborough, Robert MThe American journal of cardiology, 1997-08, Vol.80 (4), p.11B-20B [Periódico revisado por pares]New York, NY: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues: Highly Potent Selective Estrogen Receptor ModulatorsGrese, Timothy A. ; Pennington, Lewis D. ; Sluka, James P. ; Adrian, M. Dee ; Cole, Harlan W. ; Fuson, Tina R. ; Magee, David E. ; Phillips, D. Lynn ; Rowley, Ellen R. ; Shetler, Pamela K. ; Short, Lorri L. ; Venugopalan, Murali ; Yang, Na N. ; Sato, Masahiko ; Glasebrook, Andrew L. ; Bryant, Henry U.Journal of medicinal chemistry, 1998-04, Vol.41 (8), p.1272-1283 [Periódico revisado por pares]Washington, DC: American Chemical SocietyTexto completo disponível |