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1
Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer
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Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer

JUNUTULA, Jagath R ; FLAGELLA, Kelly M ; MAI, Elaine ; LEWIS PHILLIPS, Gail D ; HIRARAGI, Hajime ; FUJI, Reina N ; TIBBITTS, Jay ; VANDLEN, Richard ; SPENCER, Susan D ; SCHELLER, Richard H ; POLAKIS, Paul ; SLIWKOWSKI, Mark X ; GRAHAM, Richard A ; PARSONS, Kathryn L ; HA, Edward ; RAAB, Helga ; BHAKTA, Sunil ; NGUYEN, Trung ; DUGGER, Debra L ; GUANGMIN LI

Clinical cancer research, 2010-10, Vol.16 (19), p.4769-4778 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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2
Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues:  Highly Potent Selective Estrogen Receptor Modulators
Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues:  Highly Potent Selective Estrogen Receptor Modulators
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Synthesis and Pharmacology of Conformationally Restricted Raloxifene Analogues:  Highly Potent Selective Estrogen Receptor Modulators

Grese, Timothy A. ; Pennington, Lewis D. ; Sluka, James P. ; Adrian, M. Dee ; Cole, Harlan W. ; Fuson, Tina R. ; Magee, David E. ; Phillips, D. Lynn ; Rowley, Ellen R. ; Shetler, Pamela K. ; Short, Lorri L. ; Venugopalan, Murali ; Yang, Na N. ; Sato, Masahiko ; Glasebrook, Andrew L. ; Bryant, Henry U.

Journal of medicinal chemistry, 1998-04, Vol.41 (8), p.1272-1283 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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3
Structure−Activity Relationships of Selective Estrogen Receptor Modulators:  Modifications to the 2-Arylbenzothiophene Core of Raloxifene
Structure−Activity Relationships of Selective Estrogen Receptor Modulators:  Modifications to the 2-Arylbenzothiophene Core of Raloxifene
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Structure−Activity Relationships of Selective Estrogen Receptor Modulators:  Modifications to the 2-Arylbenzothiophene Core of Raloxifene

Grese, Timothy A ; Cho, Stephen ; Finley, Don R ; Godfrey, Alexander G ; Jones, Charles D ; Lugar, Charles W ; Martin, Michael J ; Matsumoto, Ken ; Pennington, Lewis D ; Winter, Mark A ; Adrian, M. Dee ; Cole, Harlan W ; Magee, David E ; Phillips, D. Lynn ; Rowley, Ellen R ; Short, Lorri L ; Glasebrook, Andrew L ; Bryant, Henry U

Journal of medicinal chemistry, 1997-01, Vol.40 (2), p.146-167 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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4
Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture
Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture
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Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture

GLATT, H ; DAVIS, W ; MEINL, W ; HERMERSDÖRFER, H ; VENITT, S ; PHILLIPS, D. H

Carcinogenesis (New York), 1998-10, Vol.19 (10), p.1709-1713 [Periódico revisado por pares]

Oxford: Oxford University Press

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5
The metabolic activation of tamoxifen and α-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation
The metabolic activation of tamoxifen and α-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation
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The metabolic activation of tamoxifen and α-hydroxytamoxifen to DNA-binding species in rat hepatocytes proceeds via sulphation

DAVIS, W ; VENITT, S ; PHILLIPS, D. H

Carcinogenesis (New York), 1998-05, Vol.19 (5), p.861-866 [Periódico revisado por pares]

Oxford: Oxford University Press

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6
Lack of genotoxicity of tamoxifen in human endometrium
Lack of genotoxicity of tamoxifen in human endometrium
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Lack of genotoxicity of tamoxifen in human endometrium

CARMICHAEL, P. L ; UGWUMADU, A. H. N ; NEVEN, P ; HEWER, A. J ; POON, G. K ; PHILLIPS, D. H

Cancer research (Chicago, Ill.), 1996-04, Vol.56 (7), p.1475-1479 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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7
An immunohistochemical examination of the effects of sensitisation on the mesotelencephalic dopaminergic response to d-amphetamine
An immunohistochemical examination of the effects of sensitisation on the mesotelencephalic dopaminergic response to d-amphetamine
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An immunohistochemical examination of the effects of sensitisation on the mesotelencephalic dopaminergic response to d-amphetamine

Phillips, G.D ; Setzu, E ; Vugler, A ; Hitchcott, P.K

Neuroscience, 2003-01, Vol.117 (3), p.741-753 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes
α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes
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α-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes

PHILLIPS, D. H ; CARMICHAEL, P. L ; HEWER, A ; COLE, K. J ; POON, G. K

Cancer research (Chicago, Ill.), 1994-11, Vol.54 (21), p.5518-5522 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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9
Photochemical Synthesis of N-Arylbenzophenanthridine Selective Estrogen Receptor Modulators (SERMs)
Photochemical Synthesis of N-Arylbenzophenanthridine Selective Estrogen Receptor Modulators (SERMs)
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Photochemical Synthesis of N-Arylbenzophenanthridine Selective Estrogen Receptor Modulators (SERMs)

Grese, Timothy A ; Adrian, M. Dee ; Phillips, D. Lynn ; Shetler, Pamela K ; Short, Lorri L ; Glasebrook, Andrew L ; Bryant, Henry U

Journal of medicinal chemistry, 2001-08, Vol.44 (17), p.2857-2860 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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10
Lack of evidence for tamoxifen– and toremifene–DNA adducts in lymphocytes of treated patients
Lack of evidence for tamoxifen– and toremifene–DNA adducts in lymphocytes of treated patients
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Lack of evidence for tamoxifen– and toremifene–DNA adducts in lymphocytes of treated patients

Bartsch, Helmut ; Phillips, David H. ; Nair, Jagadeesan ; Hewer, Alan ; Meyberg-Solomeyer, Gabriele ; Grischke, Eva-Maria

Carcinogenesis (New York), 2000-04, Vol.21 (4), p.845-847 [Periódico revisado por pares]

Oxford: Oxford University Press

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