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Refinado por: Base de dados/Biblioteca: American Chemical Society Journals remover
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1
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2
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Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2

Váradi, András ; Marrone, Gina F ; Palmer, Travis C ; Narayan, Ankita ; Szabó, Márton R ; Le Rouzic, Valerie ; Grinnell, Steven G ; Subrath, Joan J ; Warner, Evelyn ; Kalra, Sanjay ; Hunkele, Amanda ; Pagirsky, Jeremy ; Eans, Shainnel O ; Medina, Jessica M ; Xu, Jin ; Pan, Ying-Xian ; Borics, Attila ; Pasternak, Gavril W ; McLaughlin, Jay P ; Majumdar, Susruta

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8381-8397 [Periódico revisado por pares]

United States: American Chemical Society

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2
Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility
Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility
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Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility

Zaveri, Nurulain T

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7011-7028 [Periódico revisado por pares]

United States

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3
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics
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Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics

Bonifazi, Alessandro ; Saab, Elizabeth ; Sanchez, Julie ; Nazarova, Antonina L ; Zaidi, Saheem A ; Jahan, Khorshada ; Katritch, Vsevolod ; Canals, Meritxell ; Lane, J Robert ; Newman, Amy Hauck

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10304-10341 [Periódico revisado por pares]

United States

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4
Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists
Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists
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Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

Pagare, Piyusha P ; Li, Mengchu ; Zheng, Yi ; Kulkarni, Abhishek S ; Obeng, Samuel ; Huang, Boshi ; Ruiz, Christian ; Gillespie, James C ; Mendez, Rolando E ; Stevens, David L ; Poklis, Justin L ; Halquist, Matthew S ; Dewey, William L ; Selley, Dana E ; Zhang, Yan

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.5095-5112 [Periódico revisado por pares]

United States: American Chemical Society

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5
Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias
Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias
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Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias

Kennedy, Nicole M ; Schmid, Cullen L ; Ross, Nicolette C ; Lovell, Kimberly M ; Yue, Zhizhou ; Chen, Yen Ting ; Cameron, Michael D ; Bohn, Laura M ; Bannister, Thomas D

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8895-8907 [Periódico revisado por pares]

United States: American Chemical Society

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6
Predicted Mode of Binding to and Allosteric Modulation of the μ‑Opioid Receptor by Kratom’s Alkaloids with Reported Antinociception In Vivo
Predicted Mode of Binding to and Allosteric Modulation of the μ‑Opioid Receptor by Kratom’s Alkaloids with Reported Antinociception In Vivo
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Predicted Mode of Binding to and Allosteric Modulation of the μ‑Opioid Receptor by Kratom’s Alkaloids with Reported Antinociception In Vivo

Zhou, Yuchen ; Ramsey, Steven ; Provasi, Davide ; El Daibani, Amal ; Appourchaux, Kevin ; Chakraborty, Soumen ; Kapoor, Abhijeet ; Che, Tao ; Majumdar, Susruta ; Filizola, Marta

Biochemistry (Easton), 2021-05, Vol.60 (18), p.1420-1429 [Periódico revisado por pares]

United States: American Chemical Society

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7
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies
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Fluorescently Labeled Morphine Derivatives for Bioimaging Studies

Lam, Raymond ; Gondin, Arisbel B ; Canals, Meritxell ; Kellam, Barrie ; Briddon, Stephen J ; Graham, Bim ; Scammells, Peter J

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1316-1329 [Periódico revisado por pares]

United States: American Chemical Society

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8
Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects
Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects
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Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects

De Neve, Jolien ; Elhabazi, Khadija ; Gonzalez, Simon ; Herby, Claire ; Schneider, Séverine ; Utard, Valérie ; Fellmann-Clauss, Rosine ; Petit-Demouliere, Nathalie ; Lecat, Sandra ; Kremer, Mélanie ; Ces, Aurelia ; Daubeuf, François ; Martin, Charlotte ; Ballet, Steven ; Bihel, Frédéric ; Simonin, Frédéric

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7603-7619 [Periódico revisado por pares]

United States: American Chemical Society

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9
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources
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Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources

Smith, Maree T ; Kong, Dehui ; Kuo, Andy ; Imam, Mohammad Z ; Williams, Craig M

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1612-1661 [Periódico revisado por pares]

United States: American Chemical Society

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10
Pharmaceutical Formulation Facilities as Sources of Opioids and Other Pharmaceuticals to Wastewater Treatment Plant Effluents
Pharmaceutical Formulation Facilities as Sources of Opioids and Other Pharmaceuticals to Wastewater Treatment Plant Effluents
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Pharmaceutical Formulation Facilities as Sources of Opioids and Other Pharmaceuticals to Wastewater Treatment Plant Effluents

Phillips, Patrick J ; Smith, Steven G ; Kolpin, D. W ; Zaugg, Steven D ; Buxton, Herbert T ; Furlong, Edward T ; Esposito, Kathleen ; Stinson, Beverley

Environmental science & technology, 2010-07, Vol.44 (13), p.4910-4916 [Periódico revisado por pares]

United States: American Chemical Society

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