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Refinado por: Base de dados/Biblioteca: Gale Academic OneFile Select remover
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Structure-based discovery of opioid analgesics with reduced side effects
Structure-based discovery of opioid analgesics with reduced side effects
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Structure-based discovery of opioid analgesics with reduced side effects

Manglik, Aashish ; Lin, Henry ; Aryal, Dipendra K ; McCorvy, John D ; Dengler, Daniela ; Corder, Gregory ; Levit, Anat ; Kling, Ralf C ; Bernat, Viachaslau ; Hübner, Harald ; Huang, Xi-Ping ; Sassano, Maria F ; Giguère, Patrick M ; Löber, Stefan ; Da Duan ; Scherrer, Grégory ; Kobilka, Brian K ; Gmeiner, Peter ; Roth, Bryan L ; Shoichet, Brian K

Nature (London), 2016-09, Vol.537 (7619), p.185-190 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Structure-based design of bitopic ligands for the µ-opioid receptor
Structure-based design of bitopic ligands for the µ-opioid receptor
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Structure-based design of bitopic ligands for the µ-opioid receptor

Faouzi, Abdelfattah ; Wang, Haoqing ; Zaidi, Saheem A ; DiBerto, Jeffrey F ; Che, Tao ; Qu, Qianhui ; Robertson, Michael J ; Madasu, Manish K ; El Daibani, Amal ; Varga, Balazs R ; Zhang, Tiffany ; Ruiz, Claudia ; Liu, Shan ; Xu, Jin ; Appourchaux, Kevin ; Slocum, Samuel T ; Eans, Shainnel O ; Cameron, Michael D ; Al-Hasani, Ream ; Pan, Ying Xian ; Roth, Bryan L ; McLaughlin, Jay P ; Skiniotis, Georgios ; Katritch, Vsevolod ; Kobilka, Brian K ; Majumdar, Susruta

Nature (London), 2023-01, Vol.613 (7945), p.767-774 [Periódico revisado por pares]

England: Nature Publishing Group

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3
A nontoxic pain killer designed by modeling of pathological receptor conformations
A nontoxic pain killer designed by modeling of pathological receptor conformations
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A nontoxic pain killer designed by modeling of pathological receptor conformations

Spahn, V. ; Del Vecchio, G. ; Labuz, D. ; Rodriguez-Gaztelumendi, A. ; Massaly, N. ; Temp, J. ; Durmaz, V. ; Sabri, P. ; Reidelbach, M. ; Machelska, H. ; Weber, M. ; Stein, C.

Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6328), p.966-969 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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4
Kratom (Mitragyna Speciosa) Liver Injury: A Comprehensive Review
Kratom (Mitragyna Speciosa) Liver Injury: A Comprehensive Review
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Kratom (Mitragyna Speciosa) Liver Injury: A Comprehensive Review

Schimmel, Jonathan ; Dart, Richard C.

Drugs (New York, N.Y.), 2020-02, Vol.80 (3), p.263-283 [Periódico revisado por pares]

Cham: Springer International Publishing

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5
Changes in Opioid-Involved Overdose Deaths by Opioid Type and Presence of Benzodiazepines, Cocaine, and Methamphetamine — 25 States, July–December 2017 to January–June 2018
Changes in Opioid-Involved Overdose Deaths by Opioid Type and Presence of Benzodiazepines, Cocaine, and Methamphetamine — 25 States, July–December 2017 to January–June 2018
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Changes in Opioid-Involved Overdose Deaths by Opioid Type and Presence of Benzodiazepines, Cocaine, and Methamphetamine — 25 States, July–December 2017 to January–June 2018

Gladden, R. Matt ; O’Donnell, Julie ; Mattson, Christine L. ; Seth, Puja

MMWR. Morbidity and mortality weekly report, 2019-08, Vol.68 (34), p.737-744

United States: Centers for Disease Control & Prevention (CDC)

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6
Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids
Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids
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Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids

Olson, Keith M ; Duron, David I ; Womer, Daniel ; Fell, Ryan ; Streicher, John M Porter, James

PloS one, 2019-06, Vol.14 (6), p.e0217371 [Periódico revisado por pares]

United States: Public Library of Science

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7
Safety benefits of 'biased' opioids scrutinized
Safety benefits of 'biased' opioids scrutinized
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Safety benefits of 'biased' opioids scrutinized

Servick, Kelly

Science (American Association for the Advancement of Science), 2020-02, Vol.367 (6481), p.966-966 [Periódico revisado por pares]

United States

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8
Liposomal bupivacaine and novel local anesthetic formulations
Liposomal bupivacaine and novel local anesthetic formulations
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Liposomal bupivacaine and novel local anesthetic formulations

Prabhakar, Amit ; Ward, Ceressa T. ; Watson, Matthew ; Sanford, Jay ; Fiza, Babar ; Moll, Vanessa ; Kaye, Rachel J. ; Morgan Hall, O. ; Cornett, Elyse M. ; Urman, Richard D. ; Kaye, Alan David

Best practice & research. Clinical anaesthesiology, 2019-12, Vol.33 (4), p.425-432 [Periódico revisado por pares]

Elsevier Ltd

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9
Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs
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Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs

Vandeputte, Marthe M. ; Walton, Sara E. ; Shuda, Sarah A. ; Papsun, Donna M. ; Krotulski, Alex J. ; Stove, Christophe P.

Analytical and bioanalytical chemistry, 2023-09, Vol.415 (21), p.5165-5180 [Periódico revisado por pares]

Berlin/Heidelberg: Springer Berlin Heidelberg

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10
Fentanyl Formulations in the Management of Pain: An Update
Fentanyl Formulations in the Management of Pain: An Update
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Fentanyl Formulations in the Management of Pain: An Update

Schug, Stephan A. ; Ting, Sonya

Drugs (New York, N.Y.), 2017-05, Vol.77 (7), p.747-763 [Periódico revisado por pares]

Cham: Springer International Publishing

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