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Material Type: Artigo
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Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in MiceSahn, James J ; Mejia, Galo L ; Ray, Pradipta R ; Martin, Stephen F ; Price, Theodore JACS chemical neuroscience, 2017-08, Vol.8 (8), p.1801-1811 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Characterization of a Potential KOR/DOR Dual Agonist with No Apparent Abuse Liability via a Complementary Structure–Activity Relationship Study on Nalfurafine AnaloguesLi, Mengchu ; Stevens, David L. ; Arriaga, Michelle ; Townsend, E. Andrew ; Mendez, Rolando E. ; Blajkevch, Nadejda A. ; Selley, Dana E. ; Banks, Matthew L. ; Negus, S. Stevens ; Dewey, William L. ; Zhang, YanACS chemical neuroscience, 2022-12, Vol.13 (24), p.3608-3628 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Recent Advances in the Realm of Allosteric Modulators for Opioid Receptors for Future TherapeuticsRemesic, Michael ; Hruby, Victor J ; Porreca, Frank ; Lee, Yeon SunACS chemical neuroscience, 2017-06, Vol.8 (6), p.1147-1158 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Molecular Docking, Molecular Dynamics, and Structure–Activity Relationship Explorations of 14-Oxygenated N‑Methylmorphinan-6-ones as Potent μ‑Opioid Receptor AgonistsNoha, Stefan M ; Schmidhammer, Helmut ; Spetea, MarianaACS chemical neuroscience, 2017-06, Vol.8 (6), p.1327-1337 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Structure–Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the “Message-Address Concept” To Comprehend Their Functional ConversionObeng, Samuel ; Wang, Huiqun ; Jali, Abdulmajeed ; Stevens, David L ; Akbarali, Hamid I ; Dewey, William L ; Selley, Dana E ; Zhang, YanACS chemical neuroscience, 2019-03, Vol.10 (3), p.1075-1090 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder TreatmentObeng, Samuel ; Jali, Abdulmajeed ; Zheng, Yi ; Wang, Huiqun ; Schwienteck, Kathryn L ; Chen, Chongguang ; Stevens, David L ; Akbarali, Hamid I ; Dewey, William L ; Banks, Mathew L ; Liu-Chen, Lee-Yuan ; Selley, Dana E ; Zhang, YanACS chemical neuroscience, 2019-05, Vol.10 (5), p.2518-2532 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Structure–Activity Relationship Studies of Functionally Selective Kappa Opioid Receptor Agonists that Modulate ERK 1/2 Phosphorylation While Preserving G Protein Over βArrestin2 Signaling BiasLovell, Kimberly M ; Frankowski, Kevin J ; Stahl, Edward L ; Slauson, Stephen R ; Yoo, Euna ; Prisinzano, Thomas E ; Aubé, Jeffrey ; Bohn, Laura MACS chemical neuroscience, 2015-08, Vol.6 (8), p.1411-1419 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Identification of the First Marine-Derived Opioid Receptor “Balanced” Agonist with a Signaling Profile That Resembles the EndorphinsJohnson, Tyler A ; Milan-Lobo, Laura ; Che, Tao ; Ferwerda, Madeline ; Lambu, Eptisam ; McIntosh, Nicole L ; Li, Fei ; He, Li ; Lorig-Roach, Nicholas ; Crews, Phillip ; Whistler, Jennifer LACS chemical neuroscience, 2017-03, Vol.8 (3), p.473-485 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Caged Naloxone: Synthesis, Characterization, and Stability of 3‑O‑(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX)Lewin, Anita H ; Fix, Scott E ; Zhong, Desong ; Mayer, Louise D ; Burgess, Jason P ; Mascarella, S. Wayne ; Reddy, P. Anantha ; Seltzman, Herbert H ; Carroll, F. IvyACS chemical neuroscience, 2018-03, Vol.9 (3), p.563-567 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Combined Glia Inhibition and Opioid Receptor Agonism Afford Highly Potent Analgesics without ToleranceAkgün, Eyup ; Lunzer, Mary M ; Portoghese, Philip SACS chemical neuroscience, 2019-04, Vol.10 (4), p.2004-2011 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |