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Refinado por: Nome da Publicação: Journal Of Medicinal Chemistry remover
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1
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2
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Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β‑Arrestin‑2

Váradi, András ; Marrone, Gina F ; Palmer, Travis C ; Narayan, Ankita ; Szabó, Márton R ; Le Rouzic, Valerie ; Grinnell, Steven G ; Subrath, Joan J ; Warner, Evelyn ; Kalra, Sanjay ; Hunkele, Amanda ; Pagirsky, Jeremy ; Eans, Shainnel O ; Medina, Jessica M ; Xu, Jin ; Pan, Ying-Xian ; Borics, Attila ; Pasternak, Gavril W ; McLaughlin, Jay P ; Majumdar, Susruta

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8381-8397 [Periódico revisado por pares]

United States: American Chemical Society

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2
Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility
Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility
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Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility

Zaveri, Nurulain T

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7011-7028 [Periódico revisado por pares]

United States

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3
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics
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Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D 3 (D 3 R) and μ-Opioid (MOR) Receptor Ligands as Potentially Safer Analgesics

Bonifazi, Alessandro ; Saab, Elizabeth ; Sanchez, Julie ; Nazarova, Antonina L ; Zaidi, Saheem A ; Jahan, Khorshada ; Katritch, Vsevolod ; Canals, Meritxell ; Lane, J Robert ; Newman, Amy Hauck

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10304-10341 [Periódico revisado por pares]

United States

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4
Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists
Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists
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Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

Pagare, Piyusha P ; Li, Mengchu ; Zheng, Yi ; Kulkarni, Abhishek S ; Obeng, Samuel ; Huang, Boshi ; Ruiz, Christian ; Gillespie, James C ; Mendez, Rolando E ; Stevens, David L ; Poklis, Justin L ; Halquist, Matthew S ; Dewey, William L ; Selley, Dana E ; Zhang, Yan

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.5095-5112 [Periódico revisado por pares]

United States: American Chemical Society

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5
Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias
Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias
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Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias

Kennedy, Nicole M ; Schmid, Cullen L ; Ross, Nicolette C ; Lovell, Kimberly M ; Yue, Zhizhou ; Chen, Yen Ting ; Cameron, Michael D ; Bohn, Laura M ; Bannister, Thomas D

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8895-8907 [Periódico revisado por pares]

United States: American Chemical Society

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6
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies
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Fluorescently Labeled Morphine Derivatives for Bioimaging Studies

Lam, Raymond ; Gondin, Arisbel B ; Canals, Meritxell ; Kellam, Barrie ; Briddon, Stephen J ; Graham, Bim ; Scammells, Peter J

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.1316-1329 [Periódico revisado por pares]

United States: American Chemical Society

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7
Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects
Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects
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Multitarget μ‑Opioid Receptor AgonistsNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects

De Neve, Jolien ; Elhabazi, Khadija ; Gonzalez, Simon ; Herby, Claire ; Schneider, Séverine ; Utard, Valérie ; Fellmann-Clauss, Rosine ; Petit-Demouliere, Nathalie ; Lecat, Sandra ; Kremer, Mélanie ; Ces, Aurelia ; Daubeuf, François ; Martin, Charlotte ; Ballet, Steven ; Bihel, Frédéric ; Simonin, Frédéric

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7603-7619 [Periódico revisado por pares]

United States: American Chemical Society

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8
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources
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Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources

Smith, Maree T ; Kong, Dehui ; Kuo, Andy ; Imam, Mohammad Z ; Williams, Craig M

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1612-1661 [Periódico revisado por pares]

United States: American Chemical Society

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9
Natural Products in Medicine: Transformational Outcome of Synthetic Chemistry
Natural Products in Medicine: Transformational Outcome of Synthetic Chemistry
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Natural Products in Medicine: Transformational Outcome of Synthetic Chemistry

Szychowski, Janek ; Truchon, Jean-François ; Bennani, Youssef L

Journal of medicinal chemistry, 2014-11, Vol.57 (22), p.9292-9308 [Periódico revisado por pares]

United States: American Chemical Society

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10
Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development
Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development
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Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development

Nguyen, Thuy ; Marusich, Julie ; Li, Jun-Xu ; Zhang, Yanan

Journal of medicinal chemistry, 2020-11, Vol.63 (21), p.12387-12402 [Periódico revisado por pares]

United States: American Chemical Society

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