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Material Type: Artigo
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A novel retinoblastoma therapy from genomic and epigenetic analysesJINGHUI ZHANG ; BENAVENTE, Claudia A ; BRENNAN, Rachel ; RUSCH, Michael ; MANNING, Amity L ; JING MA ; EASTON, John ; SHURTLEFF, Sheila ; MULLIGHAN, Charles ; POUNDS, Stanley ; MUKATIRA, Suraj ; GUPTA, Pankaj ; MCEVOY, Justina ; NEALE, Geoff ; ZHAO, David ; LU, Charles ; FULTON, Robert S ; FULTON, Lucinda L ; XIN HONG ; DOOLING, David J ; OCHOA, Kerri ; NAEVE, Clayton ; DYSON, Nicholas J ; FLORES-OTERO, Jacqueline ; MARDIS, Elaine R ; BAHRAMI, Armita ; ELLISON, David ; WILSON, Richard K ; DOWNING, James R ; DYER, Michael A ; LI DING ; XIANG CHEN ; ULYANOV, Anatoly ; GANG WU ; WILSON, Matthew ; JIANMIN WANGNature (London), 2012-01, Vol.481 (7381), p.329-334 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 actionCai, Erica P. ; Luk, Cynthia T. ; Wu, Xiaohong ; Schroer, Stephanie A. ; Shi, Sally Yu ; Sivasubramaniyam, Tharini ; Brunt, Jara J. ; Zacksenhaus, Eldad ; Woo, MinnaDiabetologia, 2014-12, Vol.57 (12), p.2555-2565 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Regulation of Matrix Metalloproteinase Genes by E2F Transcription Factors: Rb-Raf-1 Interaction as a Novel Target for Metastatic DiseaseJOHNSON, Jackie L ; PILLAI, Smitha ; PERNAZZA, Danielle ; SEBTI, Saïd M ; LAWRENCE, Nicholas J ; CHELLAPPAN, Srikumar PCancer research (Chicago, Ill.), 2012-01, Vol.72 (2), p.516-526 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Identification of genes associated with tumorigenesis of retinoblastoma by microarray analysisChakraborty, Sanjukta ; Khare, Sonal ; Dorairaj, Syril Kumar ; Prabhakaran, Venkatesh C. ; Prakash, D. Ravi ; Kumar, ArunGenomics (San Diego, Calif.), 2007-09, Vol.90 (3), p.344-353 [Periódico revisado por pares]San Diego, CA: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Loss of the retinoblastoma tumor suppressor: differential action on transcriptional programs related to cell cycle control and immune functionMARKEY, M. P ; BERGSEID, J ; JEGGA, A. G ; ARONOW, B. J ; REED, M. F ; WANG, J. Y. J ; KNUDSEN, E. S ; BOSCO, E. E ; STENGEL, K ; XU, H ; MAYHEW, C. N ; SCHWEMBERGER, S. J ; BRADEN, W. A ; JIANG, Y ; BABCOCK, G. FOncogene, 2007-09, Vol.26 (43), p.6307-6318 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell linesKITAGAWA, M ; AONUMA, M ; LEE, S. H ; FUKUTAKE, S ; MCCORMICK, FOncogene, 2008-09, Vol.27 (40), p.5303-5314 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Most Basal-like Breast Carcinomas Demonstrate the Same Rb-/p16+ Immunophenotype as the HPV-related Poorly Differentiated Squamous Cell Carcinomas Which They Resemble MorphologicallyPROCTOR SUBHAWONG, Andrea ; SUBHAWONG, Ty ; NASSAR, Hind ; KOUPRINA, Nina ; BEGUM, Shahnaz ; VANG, Russell ; WESTRA, William H ; ARGANI, PedramThe American journal of surgical pathology, 2009-02, Vol.33 (2), p.163-175 [Periódico revisado por pares]Hagerstown, MD: Lippincott Williams & WilkinsTexto completo disponível |
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Material Type: Artigo
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Regulation of flowering time by FVE, a retinoblastoma-associated proteinAlonso-Blanco, Carlos ; Ruiz-García, Leonor ; Martínez-Zapater, José M ; Ausín, Israel ; Jarillo, José ANature genetics, 2004-02, Vol.36 (2), p.162-166 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosisDELSTON, R. B ; MATATALL, K. A ; SUN, Y ; ONKEN, M. D ; HARBOUR, J. WOncogene, 2011-02, Vol.30 (5), p.588-599 [Periódico revisado por pares]Basingstoke: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1 S transition during the cell cycleJEANBLANC, Michaël ; MOUSLI, Marc ; HOPFNER, Raphaël ; BATHAMI, Kawtar ; MARTINET, Nadine ; ABBADY, Abdul-Qader ; SIFFERT, Jean-Claude ; MATHIEU, Eric ; MULLER, Christian D ; BRONNER, ChristianOncogene, 2005-11, Vol.24 (49), p.7337-7345 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |