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11
Molecular docking approach for the design and synthesis of new pyrazolopyrimidine analogs of roscovitine as potential CDK2 inhibitors endowed with pronounced anticancer activity
Molecular docking approach for the design and synthesis of new pyrazolopyrimidine analogs of roscovitine as potential CDK2 inhibitors endowed with pronounced anticancer activity
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Molecular docking approach for the design and synthesis of new pyrazolopyrimidine analogs of roscovitine as potential CDK2 inhibitors endowed with pronounced anticancer activity

Hamed, Ola Alaa ; Abou-Elmagd El-Sayed, Nehad ; Mahmoud, Walaa R. ; F. Elmasry, Ghada

Bioorganic chemistry, 2024-06, Vol.147, p.107413-107413, Article 107413 [Periódico revisado por pares]

United States: Elsevier Inc

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12
Design and Synthesis of New Thiophene/Thieno[2,3- d ]pyrimidines along with Their Cytotoxic Biological Evaluation as Tyrosine Kinase Inhibitors in Addition to Their Apoptotic and Autophagic Induction
Design and Synthesis of New Thiophene/Thieno[2,3- d ]pyrimidines along with Their Cytotoxic Biological Evaluation as Tyrosine Kinase Inhibitors in Addition to Their Apoptotic and Autophagic Induction
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Design and Synthesis of New Thiophene/Thieno[2,3- d ]pyrimidines along with Their Cytotoxic Biological Evaluation as Tyrosine Kinase Inhibitors in Addition to Their Apoptotic and Autophagic Induction

Elmongy, Elshaymaa I ; Attallah, Nashwah G M ; Altwaijry, Najla ; AlKahtani, Manal Mubarak ; Henidi, Hanan Ali

Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.123 [Periódico revisado por pares]

Switzerland: MDPI AG

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13
Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation
Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation
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Design and synthesis of new 1,6-dihydropyrimidin-2-thio derivatives targeting VEGFR-2: Molecular docking and antiproliferative evaluation

Marzouk, Adel A. ; Abdel-Aziz, Salah A. ; Abdelrahman, Kamal S. ; Wanas, Amira S. ; Gouda, Ahmed M. ; Youssif, Bahaa G.M. ; Abdel-Aziz, Mohamed

Bioorganic chemistry, 2020-09, Vol.102, p.104090, Article 104090 [Periódico revisado por pares]

United States: Elsevier Inc

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14
Synthesis and anticancer activity of some pyrimidine derivatives with aryl urea moieties as apoptosis-inducing agents
Synthesis and anticancer activity of some pyrimidine derivatives with aryl urea moieties as apoptosis-inducing agents
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Synthesis and anticancer activity of some pyrimidine derivatives with aryl urea moieties as apoptosis-inducing agents

Kilic-Kurt, Zühal ; Ozmen, Nuri ; Bakar-Ates, Filiz

Bioorganic chemistry, 2020-08, Vol.101, p.104028-104028, Article 104028 [Periódico revisado por pares]

United States: Elsevier Inc

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15
DFT/B3LYP calculations, in vitro cytotoxicity and antioxidant activities of steroidal pyrimidines and their interaction with HSA using molecular docking and multispectroscopic techniques
DFT/B3LYP calculations, in vitro cytotoxicity and antioxidant activities of steroidal pyrimidines and their interaction with HSA using molecular docking and multispectroscopic techniques
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DFT/B3LYP calculations, in vitro cytotoxicity and antioxidant activities of steroidal pyrimidines and their interaction with HSA using molecular docking and multispectroscopic techniques

Ali, Abad ; Asif, Mohd ; Alam, Parvez ; Jane Alam, Mohammad ; Asif Sherwani, Mohd ; Hasan Khan, Rizwan ; Ahmad, Shabbir ; Shamsuzzaman

Bioorganic chemistry, 2017-08, Vol.73, p.83-99 [Periódico revisado por pares]

United States: Elsevier Inc

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16
Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma
Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma
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Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma

Elshaier, Yaseen A.M.M. ; Shaaban, Mohamed A. ; Abd El Hamid, Mohammed K. ; Abdelrahman, Mostafa H. ; Abou-Salim, Mahrous A. ; Elgazwi, Sara M. ; Halaweish, Fathi

Bioorganic & medicinal chemistry, 2017-06, Vol.25 (12), p.2956-2970 [Periódico revisado por pares]

England: Elsevier Ltd

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17
Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity
Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity
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Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity

Ali, Ghada M.E. ; Ibrahim, Diaa A. ; Elmetwali, Amira M. ; Ismail, Nasser S.M.

Bioorganic chemistry, 2019-05, Vol.86, p.1-14 [Periódico revisado por pares]

United States: Elsevier Inc

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18
Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile
Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile
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Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile

Mghwary, Aml E.-S. ; Gedawy, Ehab M. ; Kamal, Aliaa M. ; Abuel-Maaty, Suzan M.

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.838-852 [Periódico revisado por pares]

England: Taylor & Francis

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19
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors
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Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors

Cherukupalli, Srinivasulu ; Chandrasekaran, Balakumar ; Kryštof, Vladimír ; Aleti, Rajeshwar Reddy ; Sayyad, Nisar ; Merugu, Srinivas Reddy ; Kushwaha, Narva Deshwar ; Karpoormath, Rajshekhar

Bioorganic chemistry, 2018-09, Vol.79, p.46-59 [Periódico revisado por pares]

United States: Elsevier Inc

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20
Pyrimidine Derivative Schiff Base Ligand Stabilized Copper and Nickel Nanoparticles by Two Step Phase Transfer Method; in Vitro Anticancer, Antioxidant, Anti-Microbial and DNA Interactions
Pyrimidine Derivative Schiff Base Ligand Stabilized Copper and Nickel Nanoparticles by Two Step Phase Transfer Method; in Vitro Anticancer, Antioxidant, Anti-Microbial and DNA Interactions
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Pyrimidine Derivative Schiff Base Ligand Stabilized Copper and Nickel Nanoparticles by Two Step Phase Transfer Method; in Vitro Anticancer, Antioxidant, Anti-Microbial and DNA Interactions

P, Adwin Jose ; M, Sankarganesh ; J, Dhaveethu Raja ; S, Sukkur Saleem

Journal of fluorescence, 2020-05, Vol.30 (3), p.471-482 [Periódico revisado por pares]

New York: Springer US

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