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Expanding the medicinally relevant chemical space with compound libraries
Expanding the medicinally relevant chemical space with compound libraries
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Expanding the medicinally relevant chemical space with compound libraries

López-Vallejo, Fabian ; Giulianotti, Marc A. ; Houghten, Richard A. ; Medina-Franco, José L.

Drug discovery today, 2012-07, Vol.17 (13-14), p.718-726 [Periódico revisado por pares]

Kidlington: Elsevier Ltd

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2
Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents
Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents
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Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents

Subhedar, Dnyaneshwar D. ; Shaikh, Mubarak H. ; Arkile, Manisha A. ; Yeware, Amar ; Sarkar, Dhiman ; Shingate, Bapurao B.

Bioorganic & medicinal chemistry letters, 2016-04, Vol.26 (7), p.1704-1708 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Library Design for Fragment Based Screening
Library Design for Fragment Based Screening
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Library Design for Fragment Based Screening

Schuffenhauer, Ansgar ; Ruedisser, Simon ; Marzinzik, Andreas L ; Jahnke, Wolfgang ; Blommers, Marcel ; Selzer, Paul ; Jacoby, Edgar

Current topics in medicinal chemistry, 2005-01, Vol.5 (8), p.751-762 [Periódico revisado por pares]

United Arab Emirates: Bentham Science Publishers Ltd

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4
Selective Optimization of Side Activities:  Another Way for Drug Discovery
Selective Optimization of Side Activities:  Another Way for Drug Discovery
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Selective Optimization of Side Activities:  Another Way for Drug Discovery

Wermuth, Camille G

Journal of medicinal chemistry, 2004-03, Vol.47 (6), p.1303-1314 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Chemical Space of DNA-Encoded Libraries
Chemical Space of DNA-Encoded Libraries
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Chemical Space of DNA-Encoded Libraries

Franzini, Raphael M ; Randolph, Cassie

Journal of medicinal chemistry, 2016-07, Vol.59 (14), p.6629-6644 [Periódico revisado por pares]

United States

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6
Bis-Acridines as Lead Antiparasitic Agents: Structure-Activity Analysis of a Discrete Compound Library In Vitro
Bis-Acridines as Lead Antiparasitic Agents: Structure-Activity Analysis of a Discrete Compound Library In Vitro
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Bis-Acridines as Lead Antiparasitic Agents: Structure-Activity Analysis of a Discrete Compound Library In Vitro

CAFFREY, Conor R ; STEVERDING, Dietmar ; LAND, Kirkwood M ; BEAUCHENE, Jessica ; SCHREIBER, Kimberly ; MOLL, Heidrun ; PONTE-SUCRE, Alicia ; SCHIRMEISTER, Tanja ; SARAVANAMUTHU, Ahilan ; FAIRLAMB, Alan H ; COHEN, Fred E ; MCKERROW, James H ; SWENERTON, Ryan K ; WEISMAN, Jennifer L ; MAY, Barnaby C. H ; KELLY, Ben ; WALSHE, Deirdre ; DEBNATH, Anjan ; ZHOU, Yuan-Min ; DOYLE, Patricia S ; FAFARMAN, Aaron T ; ZORN, Julie A

Antimicrobial Agents and Chemotherapy, 2007-06, Vol.51 (6), p.2164-2172 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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7
A library of novel hydroxamic acids targeting the metallo-protease family: Design, parallel synthesis and screening
A library of novel hydroxamic acids targeting the metallo-protease family: Design, parallel synthesis and screening
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A library of novel hydroxamic acids targeting the metallo-protease family: Design, parallel synthesis and screening

Flipo, Marion ; Beghyn, Terence ; Charton, Julie ; Leroux, Virginie A. ; Deprez, Benoit P. ; Deprez-Poulain, Rebecca F.

Bioorganic & medicinal chemistry, 2007, Vol.15 (1), p.63-76 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors
Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors
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Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors

Nærum, Lars ; Nørskov-Lauritsen, Leif ; Olesen, Preben H

Bioorganic & medicinal chemistry letters, 2002-06, Vol.12 (11), p.1525-1528 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Application of Pictet–Spengler Reaction to Indole-Based Alkaloids Containing Tetrahydro-β-carboline Scaffold in Combinatorial Chemistry
Application of Pictet–Spengler Reaction to Indole-Based Alkaloids Containing Tetrahydro-β-carboline Scaffold in Combinatorial Chemistry
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Application of Pictet–Spengler Reaction to Indole-Based Alkaloids Containing Tetrahydro-β-carboline Scaffold in Combinatorial Chemistry

Rao, R. Nishanth ; Maiti, Barnali ; Chanda, Kaushik

ACS combinatorial science, 2017-04, Vol.19 (4), p.199-228 [Periódico revisado por pares]

United States: American Chemical Society

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10
Simulated Screens of DNA Encoded Libraries: The Potential Influence of Chemical Synthesis Fidelity on Interpretation of Structure–Activity Relationships
Simulated Screens of DNA Encoded Libraries: The Potential Influence of Chemical Synthesis Fidelity on Interpretation of Structure–Activity Relationships
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Simulated Screens of DNA Encoded Libraries: The Potential Influence of Chemical Synthesis Fidelity on Interpretation of Structure–Activity Relationships

Satz, Alexander L.

ACS combinatorial science, 2016-07, Vol.18 (7), p.415-424 [Periódico revisado por pares]

United States: American Chemical Society

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