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1
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
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Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects

STONE, Nimalie D ; DUNAWAY, Shelia B ; PARK, Jeong-Gun ; LALAMA, Christina ; SNYDER, Sally ; KALLUNGAL, Beatrice ; KLINGMAN, Karin L ; HENDRIX, Craig W ; FLEXNER, Charles ; TIERNEY, Camlin ; CALANDRA, Gary B ; BECKER, Stephen ; CAO, Ying-Jun ; WIGGINS, Ilene P ; CONLEY, Jeanne ; MACFARLAND, Ron T

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2351-2358 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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2
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects
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Multiple-Dose Escalation Study of the Safety, Pharmacokinetics, and Biologic Activity of Oral AMD070, a Selective CXCR4 Receptor Inhibitor, in Human Subjects

Stone, Nimalie D ; Dunaway, Shelia B ; Flexner, Charles ; Tierney, Camlin ; Calandra, Gary B ; Becker, Stephen ; Cao, Ying-Jun ; Wiggins, Ilene P ; Conley, Jeanne ; MacFarland, Ron T ; Park, Jeong-Gun ; Lalama, Christina ; Snyder, Sally ; Kallungal, Beatrice ; Klingman, Karin L ; Hendrix, Craig W

Antimicrobial agents and chemotherapy, 2007-08, Vol.51 (8), p.3047-3047 [Periódico revisado por pares]

American Society for Microbiology

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3
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model
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Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model

Burroughs, Lauri ; Mielcarek, Marco ; Little, Marie-Térèse ; Bridger, Gary ; MacFarland, Ron ; Fricker, Simon ; Labrecque, Jean ; Sandmaier, Brenda M. ; Storb, Rainer

Blood, 2005-12, Vol.106 (12), p.4002-4008 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1
Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1
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Proof of Activity with AMD11070, an Orally Bioavailable Inhibitor of CXCR4-Tropic HIV Type 1

Moyle, Graeme ; DeJesus, Edwin ; Boffito, Marta ; Wong, Rebecca S. ; Gibney, Colleen ; Badel, Karin ; MacFarland, Ron ; Calandra, Gary ; Bridger, Gary ; Becker, Stephen

Clinical infectious diseases, 2009-03, Vol.48 (6), p.798-805 [Periódico revisado por pares]

Oxford: The University of Chicago Press

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5
Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers
Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers
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Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers

YING JUN CAO ; FLEXNER, Charles W ; BECKER, Stephen ; HENDRIX, Craig W ; DUNAWAY, Shelia ; PARK, Jeong-Gun ; KLINGMAN, Karin ; WIGGINS, Ilene ; CONLEY, Jeanne ; RADEBAUGH, Christine ; KASHUBA, Angela D ; MACFARLAND, Ron

Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1630-1634 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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6
A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma
A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma
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A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma

Cashen, Amanda ; Lopez, Sandra ; Gao, Feng ; Calandra, Gary ; MacFarland, Ron ; Badel, Karin ; DiPersio, John

Biology of blood and marrow transplantation, 2008-11, Vol.14 (11), p.1253-1261

United States: Elsevier Inc

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7
A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients
A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients
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A Mobilizing Regimen of AMD3100 and G-CSF Increases Stem Cell Collection in Patients with Hodgkin's Disease, and PK Is Similar to That of Non-Cancer Patients

Cashen, Amanda F. ; Calandra, Gary ; MacFarland, Ron ; Lopez, Sandra ; DiPersio, John F.

Blood, 2006-11, Vol.108 (11), p.3053-3053 [Periódico revisado por pares]

Elsevier Inc

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8
Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma
Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma
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Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma

Stewart, Douglas A ; Smith, Clayton ; MacFarland, Ron ; Calandra, Gary

Biology of blood and marrow transplantation, 2009, Vol.15 (1), p.39-46

United States: Elsevier Inc

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9
Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication
Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication
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Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication

Skerlj, Renato ; Bridger, Gary ; Zhou, Yuanxi ; Bourque, Elyse ; McEachern, Ernest ; Danthi, Sanjay ; Langille, Jonathan ; Harwig, Curtis ; Veale, Duane ; Carpenter, Bryon ; Ba, Tuya ; Bey, Michael ; Baird, Ian ; Wilson, Trevor ; Metz, Markus ; MacFarland, Ron ; Mosi, Renee ; Bodart, Veronique ; Wong, Rebecca ; Fricker, Simon ; Huskens, Dana ; Schols, Dominique

ACS medicinal chemistry letters, 2012-03, Vol.3 (3), p.216-221 [Periódico revisado por pares]

United States: American Chemical Society

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10
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary
Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary
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Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Commentary

DEVINE, Steven M ; BURROUGHS, Lauri ; MIELCAREK, Marco ; LITTLE, Marie-Térèse ; BRIDGER, Gary ; MACFARLAND, Ron ; FRICKER, Simon ; LABRECQUE, Jean ; SANDMAIER, Brenda M ; STORB, Rainer

Blood, 2005, Vol.106 (12), p.4002-3686 [Periódico revisado por pares]

Washington, DC: The Americain Society of Hematology

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