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Material Type: Artigo
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALSYu, Chien-Hsiung ; Davidson, Sophia ; Harapas, Cassandra R. ; Hilton, James B. ; Mlodzianoski, Michael J. ; Laohamonthonkul, Pawat ; Louis, Cynthia ; Low, Ronnie Ren Jie ; Moecking, Jonas ; De Nardo, Dominic ; Balka, Katherine R. ; Calleja, Dale J. ; Moghaddas, Fiona ; Ni, Erya ; McLean, Catriona A. ; Samson, Andre L. ; Tyebji, Shiraz ; Tonkin, Christopher J. ; Bye, Christopher R. ; Turner, Bradley J. ; Pepin, Genevieve ; Gantier, Michael P. ; Rogers, Kelly L. ; McArthur, Kate ; Crouch, Peter J. ; Masters, Seth L.Cell, 2020-10, Vol.183 (3), p.636-649.e18 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Next-generation GRAB sensors for monitoring dopaminergic activity in vivoSun, Fangmiao ; Zhou, Jingheng ; Dai, Bing ; Qian, Tongrui ; Zeng, Jianzhi ; Li, Xuelin ; Zhuo, Yizhou ; Zhang, Yajun ; Wang, Yipan ; Qian, Cheng ; Tan, Ke ; Feng, Jiesi ; Dong, Hui ; Lin, Dayu ; Cui, Guohong ; Li, YulongNature methods, 2020-11, Vol.17 (11), p.1156-1166 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxelMao, Jun ; Song, Bo ; Shi, Yu ; Wang, Bo ; Fan, Shujun ; Yu, Xiaotang ; Tang, Jianwu ; Li, LianhongThe international journal of biochemistry & cell biology, 2013-06, Vol.45 (6), p.1064-1073 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunctionRobertson, Nahid G. ; Jones, Sherri M. ; Sivakumaran, Theru A. ; Giersch, Anne B.S. ; Jurado, Sara A. ; Call, Linda M. ; Miller, Constance E. ; Maison, Stéphane F. ; Liberman, M. Charles ; Morton, Cynthia C.Human molecular genetics, 2008-11, Vol.17 (21), p.3426-3434 [Periódico revisado por pares]Oxford: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Vav and Rac Activation in B Cell Antigen Receptor Endocytosis Involves Vav Recruitment to the Adapter Protein LABMalhotra, Shikha ; Kovats, Susan ; Zhang, Weiguo ; Coggeshall, K.MarkThe Journal of biological chemistry, 2009-12, Vol.284 (52), p.36202-36212 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomersCohen, Samuel I A ; Arosio, Paolo ; Presto, Jenny ; Kurudenkandy, Firoz Roshan ; Biverstal, Henrik ; Dolfe, Lisa ; Dunning, Christopher ; Yang, Xiaoting ; Frohm, Birgitta ; Vendruscolo, Michele ; Johansson, Jan ; Dobson, Christopher M ; Fisahn, André ; Knowles, Tuomas P J ; Linse, SaraNature structural & molecular biology, 2015-03, Vol.22 (3), p.207-213 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Personal model‐assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLDMardinoglu, Adil ; Bjornson, Elias ; Zhang, Cheng ; Klevstig, Martina ; Söderlund, Sanni ; Ståhlman, Marcus ; Adiels, Martin ; Hakkarainen, Antti ; Lundbom, Nina ; Kilicarslan, Murat ; Hallström, Björn M ; Lundbom, Jesper ; Vergès, Bruno ; Barrett, Peter Hugh R ; Watts, Gerald F ; Serlie, Mireille J ; Nielsen, Jens ; Uhlén, Mathias ; Smith, Ulf ; Marschall, Hanns‐Ulrich ; Taskinen, Marja‐Riitta ; Boren, JanMolecular systems biology, 2017-03, Vol.13 (3), p.916-n/a [Periódico revisado por pares]England: EMBO PressTexto completo disponível |
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Material Type: Artigo
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JASPAR 2022: the 9th release of the open-access database of transcription factor binding profilesCastro-Mondragon, Jaime A ; Riudavets-Puig, Rafael ; Rauluseviciute, Ieva ; Berhanu Lemma, Roza ; Turchi, Laura ; Blanc-Mathieu, Romain ; Lucas, Jeremy ; Boddie, Paul ; Khan, Aziz ; Manosalva Pérez, Nicolás ; Fornes, Oriol ; Leung, Tiffany Y ; Aguirre, Alejandro ; Hammal, Fayrouz ; Schmelter, Daniel ; Baranasic, Damir ; Ballester, Benoit ; Sandelin, Albin ; Lenhard, Boris ; Vandepoele, Klaas ; Wasserman, Wyeth W ; Parcy, François ; Mathelier, AnthonyNucleic acids research, 2022-01, Vol.50 (D1), p.D165-D173 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A PathwayPraetorius, Christian ; Grill, Christine ; Stacey, Simon N. ; Metcalf, Alexander M. ; Gorkin, David U. ; Robinson, Kathleen C. ; Van Otterloo, Eric ; Kim, Reuben S.Q. ; Bergsteinsdottir, Kristin ; Ogmundsdottir, Margret H. ; Magnusdottir, Erna ; Mishra, Pravin J. ; Davis, Sean R. ; Guo, Theresa ; Zaidi, M. Raza ; Helgason, Agnar S. ; Sigurdsson, Martin I. ; Meltzer, Paul S. ; Merlino, Glenn ; Petit, Valerie ; Larue, Lionel ; Loftus, Stacie K. ; Adams, David R. ; Sobhiafshar, Ulduz ; Emre, N.C. Tolga ; Pavan, William J. ; Cornell, Robert ; Smith, Aaron G. ; McCallion, Andrew S. ; Fisher, David E. ; Stefansson, Kari ; Sturm, Richard A. ; Steingrimsson, EirikurCell, 2013-11, Vol.155 (5), p.1022-1033 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen SusceptibilityDesai, Mahesh S. ; Seekatz, Anna M. ; Koropatkin, Nicole M. ; Kamada, Nobuhiko ; Hickey, Christina A. ; Wolter, Mathis ; Pudlo, Nicholas A. ; Kitamoto, Sho ; Terrapon, Nicolas ; Muller, Arnaud ; Young, Vincent B. ; Henrissat, Bernard ; Wilmes, Paul ; Stappenbeck, Thaddeus S. ; Núñez, Gabriel ; Martens, Eric C.Cell, 2016-11, Vol.167 (5), p.1339-1353.e21 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |