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1
High-level expression and purification of secreted forms of herpes simplex virus type 1 glycoprotein gD synthesized by baculovirus-infected insect cells
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Artigo
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High-level expression and purification of secreted forms of herpes simplex virus type 1 glycoprotein gD synthesized by baculovirus-infected insect cells

SISK, W. P ; BRADLEY, J. D ; LEIPOLD, R. J ; STOLTZFUS, A. M ; PONCE DE LEON, M ; HILF, M ; PENG, C ; COHEN, G. H ; EISENBERG, R. J

Journal of Virology, 1994-02, Vol.68 (2), p.766-775 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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2
Mathematical Model of Serine Protease Inhibition in the Tissue Factor Pathway to Thrombin (∗)
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Artigo
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Mathematical Model of Serine Protease Inhibition in the Tissue Factor Pathway to Thrombin (∗)

Leipold, Robert J. ; Bozarth, Tracy A. ; Racanelli, Adrienne L. ; Dicker, Ira B.

The Journal of biological chemistry, 1995-10, Vol.270 (43), p.25383-25387 [Periódico revisado por pares]

United States: Elsevier Inc

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3
On the dangers of adjusting the parameters values of mechanism-based mathematical models
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Artigo
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On the dangers of adjusting the parameters values of mechanism-based mathematical models

Hopkins, J C ; Leipold, R J

Journal of theoretical biology, 1996-12, Vol.183 (4), p.417-427 [Periódico revisado por pares]

England

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4
A de novo gain-of-function mutation in SCN11A causes loss of pain perception
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Artigo
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A de novo gain-of-function mutation in SCN11A causes loss of pain perception

Leipold, Enrico ; Liebmann, Lutz ; Korenke, G Christoph ; Heinrich, Theresa ; Giesselmann, Sebastian ; Baets, Jonathan ; Ebbinghaus, Matthias ; Goral, R Oliver ; Stödberg, Tommy ; Hennings, J Christopher ; Bergmann, Markus ; Altmüller, Janine ; Thiele, Holger ; Wetzel, Andrea ; Nürnberg, Peter ; Timmerman, Vincent ; De Jonghe, Peter ; Blum, Robert ; Schaible, Hans-Georg ; Weis, Joachim ; Heinemann, Stefan H ; Hübner, Christian A ; Kurth, Ingo

Nature genetics, 2013-11, Vol.45 (11), p.1399-1404 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody-Drug Conjugates with Self-Immolative Disulfide Linkers
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Artigo
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Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody-Drug Conjugates with Self-Immolative Disulfide Linkers

Pillow, Thomas H ; Schutten, Melissa ; Yu, Shang-Fan ; Ohri, Rachana ; Sadowsky, Jack ; Poon, Kirsten Achilles ; Solis, Willy ; Zhong, Fiona ; Del Rosario, Geoffrey ; Go, Mary Ann T ; Lau, Jeffrey ; Yee, Sharon ; He, Jintang ; Liu, Luna ; Ng, Carl ; Xu, Keyang ; Leipold, Douglas D ; Kamath, Amrita V ; Zhang, Donglu ; Masterson, Luke ; Gregson, Stephen J ; Howard, Philip W ; Fang, Fan ; Chen, Jinhua ; Gunzner-Toste, Janet ; Kozak, Katherine K ; Spencer, Susan ; Polakis, Paul ; Polson, Andrew G ; Flygare, John A ; Junutula, Jagath R

Molecular cancer therapeutics, 2017-05, Vol.16 (5), p.871-878 [Periódico revisado por pares]

United States: American Association for Cancer Research Inc

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6
Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice
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Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice

Jumbe, Nelson L. ; Xin, Yan ; Leipold, Douglas D. ; Crocker, Lisa ; Dugger, Debra ; Mai, Elaine ; Sliwkowski, Mark X. ; Fielder, Paul J. ; Tibbitts, Jay

Journal of pharmacokinetics and pharmacodynamics, 2010-06, Vol.37 (3), p.221-242 [Periódico revisado por pares]

Boston: Springer US

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7
E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse
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Artigo
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E-7869 (R-flurbiprofen) inhibits progression of prostate cancer in the TRAMP mouse

WECHTER, W. J ; LEIPOLD, D. D ; MURRAY, E. D ; QUIGGLE, D ; MCCRACKEN, J. D ; BARRIOS, R. S ; GREENBERG, N. M

Cancer research (Chicago, Ill.), 2000-04, Vol.60 (8), p.2203-2208 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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8
Antibody–Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo
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Antibody–Drug Conjugates Derived from Cytotoxic seco-CBI-Dimer Payloads Are Highly Efficacious in Xenograft Models and Form Protein Adducts In Vivo

Su, Dian ; Chen, Jinhua ; Cosino, Ely ; dela Cruz-Chuh, Josefa ; Davis, Helen ; Del Rosario, Geoffrey ; Figueroa, Isabel ; Goon, Leanne ; He, Jintang ; Kamath, Amrita V ; Kaur, Surinder ; Kozak, Katherine R ; Lau, Jeffrey ; Lee, Donna ; Lee, M. Violet ; Leipold, Douglas ; Liu, Luna ; Liu, Peter ; Lu, Guo-Liang ; Nelson, Chris ; Ng, Carl ; Pillow, Thomas H ; Polakis, Paul ; Polson, Andrew G ; Rowntree, Rebecca K ; Saad, Ola ; Safina, Brian ; Stagg, Nicola J ; Tercel, Moana ; Vandlen, Richard ; Vollmar, Breanna S ; Wai, John ; Wang, Tao ; Wei, BinQing ; Xu, Keyang ; Xue, Juanjuan ; Xu, Zijin ; Yan, Gang ; Yao, Hui ; Yu, Shang-Fan ; Zhang, Donglu ; Zhong, Fiona ; Dragovich, Peter S

Bioconjugate chemistry, 2019-05, Vol.30 (5), p.1356-1370 [Periódico revisado por pares]

United States: American Chemical Society

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9
Protective effects of cruciferous seed meals and hulls against colon cancer in mice
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Protective effects of cruciferous seed meals and hulls against colon cancer in mice

Barrett, Joyce E ; Klopfenstein, Carol F ; Leipold, Horst W

Cancer letters, 1998-05, Vol.127 (1), p.83-88 [Periódico revisado por pares]

Shannon: Elsevier Ireland Ltd

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10
R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer
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R-flurbiprofen chemoprevention and treatment of intestinal adenomas in the APC(Min)/+ mouse model: implications for prophylaxis and treatment of colon cancer

Wechter, W J ; Kantoci, D ; Murray, Jr, E D ; Quiggle, D D ; Leipold, D D ; Gibson, K M ; McCracken, J D

Cancer research (Chicago, Ill.), 1997-10, Vol.57 (19), p.4316 [Periódico revisado por pares]

United States

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