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1 |
Material Type: Artigo
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Rynaxypyr™: A new insecticidal anthranilic diamide that acts as a potent and selective ryanodine receptor activatorLahm, George P. ; Stevenson, Thomas M. ; Selby, Thomas P. ; Freudenberger, John H. ; Cordova, Daniel ; Flexner, Lindsey ; Bellin, Cheryl A. ; Dubas, Christine M. ; Smith, Ben K. ; Hughes, Kenneth A. ; Hollingshaus, J. Gary ; Clark, Christopher E. ; Benner, Eric A.Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6274-6279 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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2 |
Material Type: Artigo
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Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064Akwabi-Ameyaw, Adwoa ; Bass, Jonathan Y. ; Caldwell, Richard D. ; Caravella, Justin A. ; Chen, Lihong ; Creech, Katrina L. ; Deaton, David N. ; Jones, Stacey A. ; Kaldor, Istvan ; Liu, Yaping ; Madauss, Kevin P. ; Marr, Harry B. ; McFadyen, Robert B. ; Miller, Aaron B. ; III, Frank Navas ; Parks, Derek J. ; Spearing, Paul K. ; Todd, Dan ; Williams, Shawn P. ; Wisely, G. BruceBioorganic & medicinal chemistry, 2008-08, Vol.18 (15), p.4339-4343 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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3 |
Material Type: Artigo
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Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activityAngell, Richard ; Aston, Nicola M. ; Bamborough, Paul ; Buckton, Jacky B. ; Cockerill, Stuart ; deBoeck, Suzanne J. ; Edwards, Chris D. ; Holmes, Duncan S. ; Jones, Katherine L. ; Laine, Dramane I. ; Patel, Shila ; Smee, Penny A. ; Smith, Kathryn J. ; Somers, Don O. ; Walker, Ann L.Bioorganic & medicinal chemistry, 2008-08, Vol.18 (15), p.4428-4432 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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4 |
Material Type: Artigo
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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin KGauthier, Jacques Yves ; Chauret, Nathalie ; Cromlish, Wanda ; Desmarais, Sylvie ; Duong, Le T. ; Falgueyret, Jean-Pierre ; Kimmel, Donald B. ; Lamontagne, Sonia ; Léger, Serge ; LeRiche, Tammy ; Li, Chun Sing ; Massé, Frédéric ; McKay, Daniel J. ; Nicoll-Griffith, Deborah A. ; Oballa, Renata M. ; Palmer, James T. ; Percival, M. David ; Riendeau, Denis ; Robichaud, Joel ; Rodan, Gideon A. ; Rodan, Sevgi B. ; Seto, Carmai ; Thérien, Michel ; Truong, Vouy-Linh ; Venuti, Michael C. ; Wesolowski, Gregg ; Young, Robert N. ; Zamboni, Robert ; Black, W. CameronBioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.923-928 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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5 |
Material Type: Artigo
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Physiochemical drug properties associated with in vivo toxicological outcomesHughes, Jason D. ; Blagg, Julian ; Price, David A. ; Bailey, Simon ; DeCrescenzo, Gary A. ; Devraj, Rajesh V. ; Ellsworth, Edmund ; Fobian, Yvette M. ; Gibbs, Michael E. ; Gilles, Richard W. ; Greene, Nigel ; Huang, Enoch ; Krieger-Burke, Teresa ; Loesel, Jens ; Wager, Travis ; Whiteley, Larry ; Zhang, YaoBioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4872-4875 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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6 |
Material Type: Artigo
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Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitorsCuny, Gregory D. ; Yu, Paul B. ; Laha, Joydev K. ; Xing, Xuechao ; Liu, Ji-Feng ; Lai, Carol S. ; Deng, Donna Y. ; Sachidanandan, Chetana ; Bloch, Kenneth D. ; Peterson, Randall T.Bioorganic & medicinal chemistry, 2008-08, Vol.18 (15), p.4388-4392 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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7 |
Material Type: Artigo
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Synthesis and structure based optimization of novel Akt inhibitorsLippa, Blaise ; Pan, Gonghua ; Corbett, Matthew ; Li, Chao ; Kauffman, Goss S. ; Pandit, Jayvardhan ; Robinson, Shaughnessy ; Wei, Liuqing ; Kozina, Ekaterina ; Marr, Eric S. ; Borzillo, Gary ; Knauth, Elisabeth ; Barbacci-Tobin, Elsa G. ; Vincent, Patrick ; Troutman, Merin ; Baker, Deborah ; Rajamohan, Francis ; Kakar, Shefali ; Clark, Tracey ; Morris, JoelBioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3359-3363 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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8 |
Material Type: Artigo
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Synthesis and pharmacological evaluation of pyrazoline derivatives as new anti-inflammatory and analgesic agentsAmir, Mohammad ; Kumar, Harish ; Khan, Suroor A.Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.918-922 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |
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9 |
Material Type: Artigo
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Glycosidic carbonic anhydrase IX inhibitors: A sweet approach against cancerWinum, Jean-Yves ; Colinas, Pedro A. ; Supuran, Claudiu T.Bioorganic & medicinal chemistry, 2013-03, Vol.21 (6), p.1419-1426 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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10 |
Material Type: Artigo
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Carbonic anhydrase inhibitors: Interactions of phenols with the 12 catalytically active mammalian isoforms (CA I–XIV)Innocenti, Alessio ; Vullo, Daniela ; Scozzafava, Andrea ; Supuran, Claudiu T.Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1583-1587 [Periódico revisado por pares]Oxford: Elsevier LtdTexto completo disponível |