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Refinado por: Nome da Publicação: Bioorganic & Medicinal Chemistry remover assunto: General Aspects remover Bioorganic & Medicinal Chemistry Letters remover
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Synthesis and structure based optimization of novel Akt inhibitors
Synthesis and structure based optimization of novel Akt inhibitors
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Synthesis and structure based optimization of novel Akt inhibitors

Lippa, Blaise ; Pan, Gonghua ; Corbett, Matthew ; Li, Chao ; Kauffman, Goss S. ; Pandit, Jayvardhan ; Robinson, Shaughnessy ; Wei, Liuqing ; Kozina, Ekaterina ; Marr, Eric S. ; Borzillo, Gary ; Knauth, Elisabeth ; Barbacci-Tobin, Elsa G. ; Vincent, Patrick ; Troutman, Merin ; Baker, Deborah ; Rajamohan, Francis ; Kakar, Shefali ; Clark, Tracey ; Morris, Joel

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3359-3363 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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2
Imidazo[4,5- c]quinolines as inhibitors of the PI3K/PKB-pathway
Imidazo[4,5- c]quinolines as inhibitors of the PI3K/PKB-pathway
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Imidazo[4,5- c]quinolines as inhibitors of the PI3K/PKB-pathway

Stauffer, Frédéric ; Maira, Sauveur-Michel ; Furet, Pascal ; García-Echeverría, Carlos

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1027-1030 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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3
Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli
Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli
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Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli

Han, Yongbin ; Hou, Shuyu ; Simon, Karen A. ; Ren, Dacheng ; Luk, Yan-Yeung

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1006-1010 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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4
Synthesis and structure–activity relationships of metal–ligand complexes that potently inhibit cell migration
Synthesis and structure–activity relationships of metal–ligand complexes that potently inhibit cell migration
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Synthesis and structure–activity relationships of metal–ligand complexes that potently inhibit cell migration

Beshir, Anwar B. ; Guchhait, Sankar K. ; Gascón, José A. ; Fenteany, Gabriel

Bioorganic & medicinal chemistry, 2008-01, Vol.18 (2), p.498-504 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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5
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
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Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor

Han, Yongxin ; Belley, Michel ; Bayly, Christopher I. ; Colucci, John ; Dufresne, Claude ; Giroux, Andre ; Lau, Cheuk K. ; Leblanc, Yves ; McKay, Daniel ; Therien, Michel ; Wilson, Marie-Claire ; Skorey, Kathryn ; Chan, Chi-Chung ; Scapin, Giovana ; Kennedy, Brian P.

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3200-3205 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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6
Efficient synthesis and in vitro cytostatic activity of 4-substituted triazolyl-nucleosides
Efficient synthesis and in vitro cytostatic activity of 4-substituted triazolyl-nucleosides
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Efficient synthesis and in vitro cytostatic activity of 4-substituted triazolyl-nucleosides

El Akri, Khalid ; Bougrin, Khalid ; Balzarini, Jan ; Faraj, Abdesslem ; Benhida, Rachid

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6656-6659 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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7
Discovery of a potent and selective Aurora kinase inhibitor
Discovery of a potent and selective Aurora kinase inhibitor
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Discovery of a potent and selective Aurora kinase inhibitor

Oslob, Johan D. ; Romanowski, Michael J. ; Allen, Darin A. ; Baskaran, Subramanian ; Bui, Minna ; Elling, Robert A. ; Flanagan, William M. ; Fung, Amy D. ; Hanan, Emily J. ; Harris, Shannon ; Heumann, Stacey A. ; Hoch, Ute ; Jacobs, Jeffrey W. ; Lam, Joni ; Lawrence, Chris E. ; McDowell, Robert S. ; Nannini, Michelle A. ; Shen, Wang ; Silverman, Jeffrey A. ; Sopko, Michelle M. ; Tangonan, Bradley T. ; Teague, Juli ; Yoburn, Josh C. ; Yu, Chul H. ; Zhong, Min ; Zimmerman, Kristin M. ; O’Brien, Tom ; Lew, Willard

Bioorganic & medicinal chemistry, 2008-09, Vol.18 (17), p.4880-4884 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
Naphthalimide intercalators with chiral amino side chains : Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity
Naphthalimide intercalators with chiral amino side chains : Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity
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Naphthalimide intercalators with chiral amino side chains : Effects of chirality on DNA binding, photodamage and antitumor cytotoxicity

Yang, Qing ; Yang, Peng ; Qian, Xuhong ; Tong, Lianpeng

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6210-6213 [Periódico revisado por pares]

Amsterdam: Elsevier

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9
Pyrazolo[1,5- a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2
Pyrazolo[1,5- a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2
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Pyrazolo[1,5- a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2

Paruch, Kamil ; Dwyer, Michael P. ; Alvarez, Carmen ; Brown, Courtney ; Chan, Tin-Yau ; Doll, Ronald J. ; Keertikar, Kerry ; Knutson, Chad ; McKittrick, Brian ; Rivera, Jocelyn ; Rossman, Randall ; Tucker, Greg ; Fischmann, Thierry O. ; Hruza, Alan ; Madison, Vincent ; Nomeir, Amin A. ; Wang, Yaolin ; Lees, Emma ; Parry, David ; Sgambellone, Nicole ; Seghezzi, Wolfgang ; Schultz, Lesley ; Shanahan, Fran ; Wiswell, Derek ; Xu, Xiaoying ; Zhou, Quiao ; James, Ray A. ; Paradkar, Vidyadhar M. ; Park, Haengsoon ; Rokosz, Laura R. ; Stauffer, Tara M. ; Guzi, Timothy J.

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6220-6223 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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10
Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)
Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)
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Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)

Witter, David J. ; Harrington, Paul ; Wilson, Kevin J. ; Chenard, Melissa ; Fleming, Judith C. ; Haines, Brian ; Kral, Astrid M. ; Secrist, J. Paul ; Miller, Thomas A.

Bioorganic & medicinal chemistry, 2008-01, Vol.18 (2), p.726-731 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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