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Drug delivery systems functionalized with bone mineral seeking agents for bone targeted therapeutics
Drug delivery systems functionalized with bone mineral seeking agents for bone targeted therapeutics
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Drug delivery systems functionalized with bone mineral seeking agents for bone targeted therapeutics

Rotman, S.G. ; Grijpma, D.W. ; Richards, R.G. ; Moriarty, T.F. ; Eglin, D. ; Guillaume, O.

Journal of controlled release, 2018-01, Vol.269, p.88-99 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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2
Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145
Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145
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Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145

de Breij, A. ; Riool, M. ; Kwakman, P.H.S. ; de Boer, L. ; Cordfunke, R.A. ; Drijfhout, J.W. ; Cohen, O. ; Emanuel, N. ; Zaat, S.A.J. ; Nibbering, P.H. ; Moriarty, T.F.

Journal of controlled release, 2016-01, Vol.222, p.1-8 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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3
Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections
Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections
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Alginate microbeads and hydrogels delivering meropenem and bacteriophages to treat Pseudomonas aeruginosa fracture-related infections

Chen, Baixing ; Benavente, Luis Ponce ; Chittò, Marco ; Wychowaniec, Jacek K ; Post, Virginia ; D'Este, Matteo ; Constant, Caroline ; Zeiter, Stephan ; Feng, Wenli ; Moreno, Mercedes González ; Trampuz, Andrej ; Wagemans, Jeroen ; Onsea, Jolien ; Richards, R Geoff ; Lavigne, Rob ; Moriarty, T Fintan ; Metsemakers, Willem-Jan

Journal of controlled release, 2023-12, Vol.364, p.159-173 [Periódico revisado por pares]

Netherlands

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4
A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus
A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus
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A doxycycline-loaded polymer-lipid encapsulation matrix coating for the prevention of implant-related osteomyelitis due to doxycycline-resistant methicillin-resistant Staphylococcus aureus

Metsemakers, Willem-Jan ; Emanuel, Noam ; Cohen, Or ; Reichart, Malka ; Potapova, Inga ; Schmid, Tanja ; Segal, David ; Riool, Martijn ; Kwakman, Paulus H S ; de Boer, Leonie ; de Breij, Anna ; Nibbering, Peter H ; Richards, R Geoff ; Zaat, Sebastian A J ; Moriarty, T Fintan

Journal of controlled release, 2015-07, Vol.209, p.47-56 [Periódico revisado por pares]

Netherlands

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5
Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists
Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists
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Synthesis, biological evaluation, and pharmacokinetic study of prolyl-1-piperazinylacetic acid and prolyl-4-piperidinylacetic acid derivatives as VLA-4 antagonists

Chiba, Jun ; Takayama, Gensuke ; Takashi, Tohru ; Yokoyama, Mika ; Nakayama, Atsushi ; Baldwin, John J. ; McDonald, Edward ; Moriarty, Kevin J. ; Sarko, Christopher R. ; Saionz, Kurt W. ; Swanson, Robert ; Hussain, Zahid ; Wong, Angela ; Machinaga, Nobuo

Bioorganic & medicinal chemistry, 2006-04, Vol.14 (8), p.2725-2746 [Periódico revisado por pares]

England: Elsevier Ltd

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6
Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead
Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead
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Itk kinase inhibitors: Initial efforts to improve the metabolical stability and the cell activity of the benzimidazole lead

Moriarty, Kevin J. ; Winters, Michael ; Qiao, Lei ; Ryan, Declan ; DesJarlis, Renee ; Robinson, Darius ; Cook, Brian N. ; Kashem, Mohammed A. ; Kaplita, Paul V. ; Liu, Lisa H. ; Farrell, Thomas M. ; Khine, Hnin Hnin ; King, Josephine ; Pullen, Steven S. ; Roth, Gregory P. ; Magolda, Ronald ; Takahashi, Hidenori

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5537-5540 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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7
The synthesis and SAR of 2-amino-pyrrolo[2,3- d]pyrimidines: A new class of Aurora-A kinase inhibitors
The synthesis and SAR of 2-amino-pyrrolo[2,3- d]pyrimidines: A new class of Aurora-A kinase inhibitors
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The synthesis and SAR of 2-amino-pyrrolo[2,3- d]pyrimidines: A new class of Aurora-A kinase inhibitors

Moriarty, Kevin J. ; Koblish, Holly K. ; Garrabrant, Thomas ; Maisuria, Jahanvi ; Khalil, Ehab ; Ali, Farah ; Petrounia, Ioanna P. ; Crysler, Carl S. ; Maroney, Anna C. ; Johnson, Dana L. ; Galemmo, Robert A.

Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (22), p.5778-5783 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
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Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors

Qiao, Lei ; Baumann, Christian A. ; Crysler, Carl S. ; Ninan, Nisha S. ; Abad, Marta C. ; Spurlino, John C. ; DesJarlais, Renee L. ; Kervinen, Jukka ; Neeper, Mike P. ; Bayoumy, Shariff S. ; Williams, Robyn ; Deckman, Ingrid C. ; Dasgupta, Malini ; Reed, Rolanda L. ; Huebert, Norman D. ; Tomczuk, Bruce E. ; Moriarty, Kevin J.

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.123-128 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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9
Evaluation of nitrate-substituted pseudocholine esters of aspirin as potential nitro-aspirins
Evaluation of nitrate-substituted pseudocholine esters of aspirin as potential nitro-aspirins
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Evaluation of nitrate-substituted pseudocholine esters of aspirin as potential nitro-aspirins

Gilmer, John F. ; Moriarty, Louise M. ; Clancy, John M.

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3217-3220 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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10
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
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Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)

MORIARTY, Kevin J ; TAKAHASHI, Hidenori ; LEI QIAO ; RYAN, Declan ; DESJARLAIS, Renee ; ROBINSON, Darius ; WILSON, Matthew ; BOBKO, Mark ; COOK, Brian N ; HO YIN LO ; NEMOTO, Peter A ; KASHEM, Mohammed A ; PULLEN, Steven S ; WOLAK, John P ; WHITE, André ; MAGOLDA, Ronald L ; TOMCZUK, Bruce ; HNIN HNIN KHINE ; SALLATI, Rosemarie H ; RAYMOND, Ernest L ; WOSKA, Joseph R ; JEANFAVRE, Deborah D ; ROTH, Gregory P ; WINTERS, Michael P

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5545-5549 [Periódico revisado por pares]

Amsterdam: Elsevier

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