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LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors
LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors
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LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors

Kingston, A.E ; Ornstein, P.L ; Wright, R.A ; Johnson, B.G ; Mayne, N.G ; Burnett, J.P ; Belagaje, R ; Wu, S ; Schoepp, D.D

Neuropharmacology, 1998, Vol.37 (1), p.1-12 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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2
Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro
Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro
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Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro

Miu, P ; Jarvie, K.R ; Radhakrishnan, V ; Gates, M.R ; Ogden, A ; Ornstein, P.L ; Zarrinmayeh, H ; Ho, K ; Peters, D ; Grabell, J ; Gupta, A ; Zimmerman, D.M ; Bleakman, D

Neuropharmacology, 2001-06, Vol.40 (8), p.976-983 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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3
Synthesis and Evaluation of a Series of Novel 2-[(4-Chlorophenoxy)methyl]- benzimidazoles as Selective Neuropeptide Y Y1 Receptor Antagonists
Synthesis and Evaluation of a Series of Novel 2-[(4-Chlorophenoxy)methyl]- benzimidazoles as Selective Neuropeptide Y Y1 Receptor Antagonists
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Synthesis and Evaluation of a Series of Novel 2-[(4-Chlorophenoxy)methyl]- benzimidazoles as Selective Neuropeptide Y Y1 Receptor Antagonists

Zarrinmayeh, Hamideh ; Nunes, Anne M ; Ornstein, Paul L ; Zimmerman, Dennis M ; Arnold, M. Brian ; Schober, Douglas A ; Gackenheimer, Susan L ; Bruns, Robert F ; Hipskind, Philip A ; Britton, Thomas C ; Cantrell, Buddy E ; Gehlert, Donald R

Journal of medicinal chemistry, 1998-07, Vol.41 (15), p.2709-2719 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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4
Biarylpropylsulfonamides as Novel, Potent Potentiators of 2-Amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic Acid (AMPA) Receptors
Biarylpropylsulfonamides as Novel, Potent Potentiators of 2-Amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic Acid (AMPA) Receptors
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Biarylpropylsulfonamides as Novel, Potent Potentiators of 2-Amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic Acid (AMPA) Receptors

Ornstein, Paul L ; Zimmerman, Dennis M ; Arnold, M. Brian ; Bleisch, Thomas J ; Cantrell, Buddy ; Simon, Richard ; Zarrinmayeh, Hamideh ; Baker, S. Richard ; Gates, Mary ; Tizzano, Joseph P ; Bleakman, David ; Mandelzys, Allan ; Jarvie, Kieth R ; Ho, Ken ; Deverill, Michelle ; Kamboj, Rajender K

Journal of medicinal chemistry, 2000-11, Vol.43 (23), p.4354-4358 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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5
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists
Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists
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Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists

Zarrinmayeh, Hamideh ; Zimmerman, Dennis M. ; Cantrell, Buddy E. ; Schober, Douglas A. ; Bruns, Robert E. ; Gackenheimer, Susan L. ; Ornstein, Paul L. ; Hipskind, Philip A. ; Britton, Thomas C. ; Gehlert, Donald R.

Bioorganic & medicinal chemistry letters, 1999-03, Vol.9 (5), p.647-652 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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6
2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability
2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability
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2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 2. Effects of Aromatic Substitution, Pharmacological Characterization, and Bioavailability

Ornstein, Paul L ; Bleisch, Thomas J ; Arnold, M. Brian ; Kennedy, Joseph H ; Wright, Rebecca A ; Johnson, Bryan G ; Tizzano, Joseph P ; Helton, David R ; Kallman, Mary Jeanne ; Schoepp, Darryle D ; Hérin, Marc

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.358-378 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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7
2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 1. Effects of Alkyl, Arylalkyl, and Diarylalkyl Substitution
2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 1. Effects of Alkyl, Arylalkyl, and Diarylalkyl Substitution
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2-Substituted (2SR)-2-Amino-2-((1SR,2SR)-2-carboxycycloprop-1-yl)glycines as Potent and Selective Antagonists of Group II Metabotropic Glutamate Receptors. 1. Effects of Alkyl, Arylalkyl, and Diarylalkyl Substitution

Ornstein, Paul L ; Bleisch, Thomas J ; Arnold, M. Brian ; Wright, Rebecca A ; Johnson, Bryan G ; Schoepp, Darryle D

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.346-357 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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8
Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor
Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor
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Synthesis and Structure−Activity Relationships of Novel Arylpiperazines as Potent and Selective Agonists of the Melanocortin Subtype-4 Receptor

Richardson, Timothy I ; Ornstein, Paul L ; Briner, Karin ; Fisher, Matthew J ; Backer, Ryan T ; Biggers, C. Kelly ; Clay, Michael P ; Emmerson, Paul J ; Hertel, Larry W ; Hsiung, Hansen M ; Husain, Saba ; Kahl, Steven D ; Lee, Jonathan A ; Lindstrom, Terry D ; Martinelli, Michael J ; Mayer, John P ; Mullaney, Jeffery T ; O'Brien, Thomas P ; Pawlak, Joseph M ; Revell, Kevin D ; Shah, Jikesh ; Zgombick, John M ; Herr, R. Jason ; Melekhov, Alex ; Sampson, Peter B ; King, Chi-Hsin R

Journal of medicinal chemistry, 2004-01, Vol.47 (3), p.744-755 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia
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LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia

O'Neill, Michael J ; Bogaert, Liesbeth ; Hicks, Caroline A ; Bond, Ann ; Ward, Mark A ; Ebinger, Guy ; Ornstein, Paul L ; Michotte, Yvette ; Lodge, David

Neuropharmacology, 2000-01, Vol.39 (9), p.1575-1588 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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10
Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines
Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines
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Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines

Fisher, Matthew J. ; Backer, Ryan T. ; Husain, Saba ; Hsiung, Hansen M. ; Mullaney, Jeffrey T. ; O’Brian, Thomas P. ; Ornstein, Paul L. ; Rothhaar, Roger R. ; Zgombick, John M. ; Briner, Karin

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (20), p.4459-4462 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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