Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8

Walle, Thomas ; Kraske, Joscha A ; Liao, Boyu ; Lenoir, Bénédicte ; Timke, Carmen ; von Bohlen Und Halbach, Emilia ; Tran, Florian ; Griebel, Paul ; Albrecht, Dorothee ; Ahmed, Azaz ; Suarez-Carmona, Meggy ; Jiménez-Sánchez, Alejandro ; Beikert, Tizian ; Tietz-Dahlfuß, Alexandra ; Menevse, Ayse Nur ; Schmidt, Gabriele ; Brom, Manuela ; Pahl, Jens H W ; Antonopoulos, Wiebke ; Miller, Matthias ; Perez, Ramon Lopez ; Bestvater, Felix ; Giese, Nathalia A ; Beckhove, Philipp ; Rosenstiel, Philip ; Jäger, Dirk ; Strobel, Oliver ; Pe'er, Dana ; Halama, Niels ; Debus, Jürgen ; Cerwenka, Adelheid ; Huber, Peter E

United States: American Association for the Advancement of Science

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Comprehensive Benchmarking and Integration of Tumor Microenvironment Cell Estimation Methods

Jiménez-Sánchez, Alejandro ; Cast, Oliver ; Miller, Martin L

United States

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Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers

Din, Shahida ; Wong, Kim ; Mueller, Mike F ; Oniscu, Anca ; Hewinson, James ; Black, Catherine J ; Miller, Martin L ; Jiménez-Sánchez, Alejandro ; Rabbie, Roy ; Rashid, Mamunar ; Satsangi, Jack ; Adams, David J ; Arends, Mark J

United States

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Abstract 1273: Tumor progression and tumor microenvironment of pancreas cancer ascites revealed by scRNA-seq and spatial transcriptomics

Umeda, Shigeaki ; Karnoub, Elias-Ramzey ; Balogun, Fiyinfolu ; Jiménez-Sánchez, Alejandro ; Iacobuzio-Donahue, Christine A.

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Abstract IA07: UVB-induced tumor heterogeneity directs immune response in melanoma

Bartok, Osnat ; Patkar, Sushant ; Cohen, Sapir ; Litchfield, Kevin ; Karathia, Hiren ; Lee, Joo Sang ; Jiménez-Sánchez, Alejandro ; Day, Chi-Ping ; Eisenbach, Lea ; Miller, Martin ; Merlino, Glenn ; Pikarsky, Eli ; Admon, Arie ; Swanton, Charles ; Ruppin, Eytan ; Samuels, Yardena ; Wolf, Yochai

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Abstract 279: Optimal tumor metastatic gene programs in pancreatic cancer

Jiménez-Sánchez, Alejandro ; Xie, Yubin ; Sharma, Roshan ; Chu, Tin Yi ; Liu, Vincent ; Park, Wungki ; Hayashi, Akimasa ; Umeda, Shigeaki ; Mazutis, Linas ; Nawy, Tal ; Iacobuzio-Donahue, Christine ; Pe’er, Dana

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Abstract 1241: A single cell landscape of malignant pancreas cancer ascites

Umeda, Shigeaki ; Karnoub, Elias- Ramzey ; Ziv, Etay ; Wu, Jean ; Cruz, Cristian ; Park, Wungki ; Balogun, Fiyinfolu ; Sánchez, Alejandro Jiménez ; Chaligné, Ronan ; O'Reilly, Eileen M. ; Donahue, Christine A. Iacobuzio

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Abstract C65: Identifying mechanisms of macrophage-mediated metastasis and therapy resistance in PDAC

Wu, Tony J. ; Cast, Oliver ; Memon, Danish ; Jimenez-Sanchez, Alejandro ; Machel, Anne ; Kehrloesser, Sebastian ; Gill, Michael B. ; Miller, Martin L.

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Augmented Cardiac Inotropy by Phosphodiesterase Inhibition Requires Phosphorylation of Rad and Increased Calcium Current

Katchman, Alexander N ; Zakharov, Sergey I ; Bohnen, Michael S ; Sanchez Jimenez, Alejandro ; Kushner, Jared S ; Yang, Lin ; Chen, Bi-Xing ; Nasari, Amina ; Liu, Guoxia ; Rabbani, David E ; Han, Jiying ; Leu, Cheng-Shiun ; Pitt, Geoffrey S ; Marx, Steven O

United States

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Abstract B045: Deep genomic and single cell molecular profiles define immunogenic pancreatic cancer

Park, Wungki ; Umeda, Shigeaki ; O'Connor, Catherine ; Zhang, Haochen ; Sharma, Roshan ; Richards, Allison ; Zhu, Yingjie ; Karnoub, Elias-Ramzey ; Pei, Xin ; Varghese, Anna M. ; Soares, Kevin ; Sanchez, Alejandro Jimenez ; Sahin, Hulya Ozkan ; Yu, Kenneth ; Balachandran, Vinod P. ; Chou, Joanne ; Keane, Fergus ; Kelsen, David ; Basturk, Olca ; Bandlamudi, Chaitanya ; Capanu, Marinela ; Nawy, Tal ; Berger, Michael ; Chaligne, Ronan ; Abou-Alfa, Ghassan ; Reis-Filho, Jorge S. ; Riaz, Nadeem ; Pe'er, Dana ; Iacobuzio-Donahue, Christine A. ; O'Reilly, Eileen M.

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