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PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activationMotawe, Zeinab Y. ; Abdelmaboud, Salma S. ; Cuevas, Javier ; Breslin, Jerome W.The international journal of biochemistry & cell biology, 2020-09, Vol.126, p.105803-105803, Article 105803 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in ratsHong, Weimin Conrad ; Yano, Hideaki ; Hiranita, Takato ; Chin, Frederick T. ; McCurdy, Christopher R. ; Su, Tsung-Ping ; Amara, Susan G. ; Katz, Jonathan L.The Journal of biological chemistry, 2017-07, Vol.292 (27), p.11250-11261 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Effect of selective LRRK2 kinase inhibition on nonhuman primate lungFuji, Reina N ; Flagella, Michael ; Baca, Miriam ; Baptista, Marco A S ; Brodbeck, Jens ; Chan, Bryan K ; Fiske, Brian K ; Honigberg, Lee ; Jubb, Adrian M ; Katavolos, Paula ; Lee, Donna W ; Lewin-Koh, Sock-Cheng ; Lin, Tori ; Liu, Xingrong ; Liu, Shannon ; Lyssikatos, Joseph P ; O'Mahony, Jennifer ; Reichelt, Mike ; Roose-Girma, Merone ; Sheng, Zejuan ; Sherer, Todd ; Smith, Ashley ; Solon, Margaret ; Sweeney, Zachary K ; Tarrant, Jacqueline ; Urkowitz, Alison ; Warming, Søren ; Yaylaoglu, Murat ; Zhang, Shuo ; Zhu, Haitao ; Estrada, Anthony A ; Watts, Ryan JScience translational medicine, 2015-02, Vol.7 (273), p.273ra15 [Periódico revisado por pares]United StatesTexto completo disponível |
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X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetinePenmatsa, Aravind ; Wang, Kevin H ; Gouaux, EricNature structural & molecular biology, 2015-06, Vol.22 (6), p.506-508 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Molecular basis of human ATM kinase inhibitionStakyte, K ; Rotheneder, M ; Lammens, K ; Bartho, J D ; Grädler, U ; Fuchß, T ; Pehl, U ; Alt, A ; van de Logt, E ; Hopfner, K PNature structural & molecular biology, 2021-10, Vol.28 (10), p.789-798 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)García-Martínez, Juan M ; Moran, Jennifer ; Clarke, Rosemary G ; Gray, Alex ; Cosulich, Sabina C ; Chresta, Christine M ; Alessi, Dario RBiochemical journal, 2009-06, Vol.421 (1), p.29-42 [Periódico revisado por pares]England: Portland PressTexto completo disponível |
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Material Type: Artigo
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Novel cross-talk within the IKK family controls innate immunityClark, Kristopher ; Peggie, Mark ; Plater, Lorna ; Sorcek, Ronald J ; Young, Erick R R ; Madwed, Jeffrey B ; Hough, Joanne ; McIver, Edward G ; Cohen, PhilipBiochemical journal, 2011-02, Vol.434 (1), p.93-104 [Periódico revisado por pares]England: Portland PressTexto completo disponível |
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Identification of MicroRNA-93 as a Novel Regulator of Vascular Endothelial Growth Factor in Hyperglycemic ConditionsLong, Jianyin ; Wang, Yin ; Wang, Wenjian ; Chang, Benny H.J. ; Danesh, Farhad R.The Journal of biological chemistry, 2010-07, Vol.285 (30), p.23457-23465 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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The Cap-Snatching SFTSV Endonuclease Domain Is an Antiviral TargetWang, Wenjie ; Shin, Woo-Jin ; Zhang, Bojie ; Choi, Younho ; Yoo, Ji-Seung ; Zimmerman, Maxwell I. ; Frederick, Thomas E. ; Bowman, Gregory R. ; Gross, Michael L. ; Leung, Daisy W. ; Jung, Jae U. ; Amarasinghe, Gaya K.Cell reports (Cambridge), 2020-01, Vol.30 (1), p.153-163.e5 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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A synthesized heterocyclic chalcone inhibits neutrophilic inflammation through K+‐dependent pH regulationYang, Shun‐Chin ; Wang, Yi‐Hsuan ; Tsai, Yung‐Fong ; Chang, Ya‐Wen ; Wu, Tian‐Shung ; Ho, Chiu‐Ming ; Hwang, Tsong‐LongThe FASEB journal, 2020-05, Vol.34 (5), p.7127-7143 [Periódico revisado por pares]United StatesTexto completo disponível |