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1 |
Material Type: Artigo
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BIBW2992, an irreversible EGFR HER2 inhibitor highly effective in preclinical lung cancer modelsLI, D ; AMBROGIO, L ; RETTIG, W. J ; MEYERSON, M ; SOLCA, F ; GREULICH, H ; WONG, K.-K ; SHIMAMURA, T ; KUBO, S ; TAKAHASHI, M ; CHIRIEAC, L. R ; PADERA, R. F ; SHAPIRO, G. I ; BAUM, A ; HIMMELSBACH, FOncogene, 2008-08, Vol.27 (34), p.4702-4711 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Integrated Genomic Profiling of Endometrial Carcinoma Associates Aggressive Tumors with Indicators of PI3 Kinase ActivationSalvesen, H. B. ; Carter, S. L. ; Mannelqvist, M. ; Dutt, A. ; Getz, G. ; Stefansson, I. M. ; Raeder, M. B. ; Sos, M. L. ; Engelsen, I. B. ; Trovik, J. ; Wik, E. ; Greulich, H. ; Bø, T. H. ; Jonassen, I. ; Thomas, R. K. ; Zander, T. ; Garraway, L. A. ; Øyan, A. M. ; Sellers, W. R. ; Kalland, K. H. ; Meyerson, M. ; Akslen, L. A. ; Beroukhim, R. ; Gray, Joe W.Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (12), p.4834-4839 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutantsGreulich, Heidi ; Chen, Tzu-Hsiu ; Feng, Whei ; Jänne, Pasi A ; Alvarez, James V ; Zappaterra, Mauro ; Bulmer, Sara E ; Frank, David A ; Hahn, William C ; Sellers, William R ; Meyerson, Matthew Rosen, NealPLoS medicine, 2005-11, Vol.2 (11), p.e313-e313 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Activating mutations in ALK provide a therapeutic target in neuroblastomaMeyerson, Matthew ; Look, A. Thomas ; George, Rani E ; Sanda, Takaomi ; Hanna, Megan ; Fröhling, Stefan ; II, William Luther ; Zhang, Jianming ; Ahn, Yebin ; Zhou, Wenjun ; London, Wendy B ; McGrady, Patrick ; Xue, Liquan ; Zozulya, Sergey ; Gregor, Vlad E ; Webb, Thomas R ; Gray, Nathanael S ; Gilliland, D. Gary ; Diller, Lisa ; Greulich, Heidi ; Morris, Stephan WNature (London), 2008-10, Vol.455 (7215), p.975-978 [Periódico revisado por pares]London: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptorALVAREZ, James V ; GREULICH, Heidi ; SELLERS, William R ; MEYERSON, Matthew ; FRANK, David ACancer research (Chicago, Ill.), 2006-03, Vol.66 (6), p.3162-3168 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib TherapyPaez, J. Guillermo ; Jänne, Pasi A. ; Lee, Jeffrey C. ; Tracy, Sean ; Greulich, Heidi ; Gabriel, Stacey ; Herman, Paula ; Kaye, Frederic J. ; Lindeman, Neal ; Boggon, Titus J. ; Naoki, Katsuhiko ; Sasaki, Hidefumi ; Fujii, Yoshitaka ; Eck, Michael J. ; Sellers, William R. ; Johnson, Bruce E. ; Meyerson, MatthewScience (American Association for the Advancement of Science), 2004-06, Vol.304 (5676), p.1497-1500 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Characterizing genomic alterations in cancer by complementary functional associationsKim, Jong Wook ; Botvinnik, Olga B ; Abudayyeh, Omar ; Birger, Chet ; Rosenbluh, Joseph ; Shrestha, Yashaswi ; Abazeed, Mohamed E ; Hammerman, Peter S ; DiCara, Daniel ; Konieczkowski, David J ; Johannessen, Cory M ; Liberzon, Arthur ; Alizad-Rahvar, Amir Reza ; Alexe, Gabriela ; Aguirre, Andrew ; Ghandi, Mahmoud ; Greulich, Heidi ; Vazquez, Francisca ; Weir, Barbara A ; Van Allen, Eliezer M ; Tsherniak, Aviad ; Shao, Diane D ; Zack, Travis I ; Noble, Michael ; Getz, Gad ; Beroukhim, Rameen ; Garraway, Levi A ; Ardakani, Masoud ; Romualdi, Chiara ; Sales, Gabriele ; Barbie, David A ; Boehm, Jesse S ; Hahn, William C ; Mesirov, Jill P ; Tamayo, PabloNature biotechnology, 2016-05, Vol.34 (5), p.539-546 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Landscape of genomic alterations in cervical carcinomasOjesina, Akinyemi I ; Lichtenstein, Lee ; Freeman, Samuel S ; Pedamallu, Chandra Sekhar ; Imaz-Rosshandler, Ivan ; Pugh, Trevor J ; Cherniack, Andrew D ; Ambrogio, Lauren ; Cibulskis, Kristian ; Bertelsen, Bjørn ; Romero-Cordoba, Sandra ; Treviño, Victor ; Vazquez-Santillan, Karla ; Guadarrama, Alberto Salido ; Wright, Alexi A ; Rosenberg, Mara W ; Duke, Fujiko ; Kaplan, Bethany ; Wang, Rui ; Nickerson, Elizabeth ; Walline, Heather M ; Lawrence, Michael S ; Stewart, Chip ; Carter, Scott L ; McKenna, Aaron ; Rodriguez-Sanchez, Iram P ; Espinosa-Castilla, Magali ; Woie, Kathrine ; Bjorge, Line ; Wik, Elisabeth ; Halle, Mari K ; Hoivik, Erling A ; Krakstad, Camilla ; Gabiño, Nayeli Belem ; Gómez-Macías, Gabriela Sofia ; Valdez-Chapa, Lezmes D ; Garza-Rodríguez, María Lourdes ; Maytorena, German ; Vazquez, Jorge ; Rodea, Carlos ; Cravioto, Adrian ; Cortes, Maria L ; Greulich, Heidi ; Crum, Christopher P ; Neuberg, Donna S ; Hidalgo-Miranda, Alfredo ; Escareno, Claudia Rangel ; Akslen, Lars A ; Carey, Thomas E ; Vintermyr, Olav K ; Gabriel, Stacey B ; Barrera-Saldaña, Hugo A ; Melendez-Zajgla, Jorge ; Getz, Gad ; Salvesen, Helga B ; Meyerson, MatthewNature (London), 2014-02, Vol.506 (7488), p.371-375 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Mandibulofacial Dysostosis with Microcephaly: Mutation and Database UpdateHuang, Lijia ; Vanstone, Megan R. ; Hartley, Taila ; Osmond, Matthew ; Barrowman, Nick ; Allanson, Judith ; Baker, Laura ; Dabir, Tabib A. ; Dipple, Katrina M. ; Dobyns, William B. ; Estrella, Jane ; Faghfoury, Hanna ; Favaro, Francine P. ; Goel, Himanshu ; Gregersen, Pernille A. ; Gripp, Karen W. ; Grix, Art ; Guion-Almeida, Maria-Leine ; Harr, Margaret H. ; Hudson, Cindy ; Hunter, Alasdair G.W. ; Johnson, John ; Joss, Shelagh K. ; Kimball, Amy ; Kini, Usha ; Kline, Antonie D. ; Lauzon, Julie ; Lildballe, Dorte L. ; López-González, Vanesa ; Martinezmoles, Johanna ; Meldrum, Cliff ; Mirzaa, Ghayda M. ; Morel, Chantal F. ; Morton, Jenny E.V. ; Pyle, Louise C. ; Quintero-Rivera, Fabiola ; Richer, Julie ; Scheuerle, Angela E. ; Schönewolf-Greulich, Bitten ; Shears, Deborah J. ; Silver, Josh ; Smith, Amanda C. ; Temple, I. Karen ; van de Kamp, Jiddeke M. ; van Dijk, Fleur S. ; Vandersteen, Anthony M. ; White, Sue M. ; Zackai, Elaine H. ; Zou, Ruobing ; Consortium, Care4Rare Canada ; Bulman, Dennis E. ; Boycott, Kym M. ; Lines, Matthew A.Human mutation, 2016-02, Vol.37 (2), p.148-154 [Periódico revisado por pares]United States: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Somatic mutations are present in all members of the AKT family in endometrial carcinomaDutt, A ; Salvesen, H B ; Greulich, H ; Sellers, W R ; Beroukhim, R ; Meyerson, MBritish journal of cancer, 2009-10, Vol.101 (7), p.1218-1219 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |