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Refinado por: Base de dados/Biblioteca: Journals@Ovid Ovid Full Text remover
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1
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states
The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states
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The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states

Wigle, Tim J. ; Knutson, Sarah K. ; Jin, Lei ; Kuntz, Kevin W. ; Pollock, Roy M. ; Richon, Victoria M. ; Copeland, Robert A. ; Scott, Margaret Porter

FEBS letters, 2011-10, Vol.585 (19), p.3011-3014 [Periódico revisado por pares]

England: Elsevier B.V

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2
MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia
MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia
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MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia

Riedel, Simone S ; Haladyna, Jessica N ; Bezzant, Matthew ; Stevens, Brett ; Pollyea, Daniel A ; Sinha, Amit U ; Armstrong, Scott A ; Wei, Qi ; Pollock, Roy M ; Daigle, Scott R ; Jordan, Craig T ; Ernst, Patricia ; Neff, Tobias ; Bernt, Kathrin M

The Journal of clinical investigation, 2016-04, Vol.126 (4), p.1438-1450 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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3
Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L
Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L
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Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L

Basavapathruni, Aravind ; Jin, Lei ; Daigle, Scott R. ; Majer, Christina R. A. ; Therkelsen, Carly A. ; Wigle, Tim J. ; Kuntz, Kevin W. ; Chesworth, Richard ; Pollock, Roy M. ; Scott, Margaret P. ; Moyer, Mikel P. ; Richon, Victoria M. ; Copeland, Robert A. ; Olhava, Edward J.

Chemical biology & drug design, 2012-12, Vol.80 (6), p.971-980 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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4
Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target
Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target
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Exploring drug delivery for the DOT1L inhibitor pinometostat (EPZ-5676): Subcutaneous administration as an alternative to continuous IV infusion, in the pursuit of an epigenetic target

Waters, Nigel J. ; Daigle, Scott R. ; Rehlaender, Bruce N. ; Basavapathruni, Aravind ; Campbell, Carly T. ; Jensen, Tyler B. ; Truitt, Brett F. ; Olhava, Edward J. ; Pollock, Roy M. ; Stickland, Kim A. ; Dovletoglou, Angelos

Journal of controlled release, 2015-12, Vol.220 (Pt B), p.758-765 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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5
Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor
Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor
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Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor

Basavapathruni, Aravind ; Olhava, Edward J. ; Daigle, Scott R. ; Therkelsen, Carly A. ; Jin, Lei ; Boriack-Sjodin, P. Ann ; Allain, Christina J. ; Klaus, Christine R. ; Raimondi, Alejandra ; Scott, Margaret Porter ; Dovletoglou, Angelos ; Richon, Victoria M. ; Pollock, Roy M. ; Copeland, Robert A. ; Moyer, Mikel P. ; Chesworth, Richard ; Pearson, Paul G. ; Waters, Nigel J.

Biopharmaceutics & drug disposition, 2014-05, Vol.35 (4), p.237-252 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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6
Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l
Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l
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Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l

Chen, L ; Deshpande, A J ; Banka, D ; Bernt, K M ; Dias, S ; Buske, C ; Olhava, E J ; Daigle, S R ; Richon, V M ; Pollock, R M ; Armstrong, S A

Leukemia, 2013-04, Vol.27 (4), p.813-822 [Periódico revisado por pares]

England: Nature Publishing Group

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7
A sensitive method for the determination of protein-DNA binding specificities
A sensitive method for the determination of protein-DNA binding specificities
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A sensitive method for the determination of protein-DNA binding specificities

POLLOCK, R ; TREISMAN, R

Nucleic acids research, 1990-11, Vol.18 (21), p.6197-6204 [Periódico revisado por pares]

Oxford: Oxford University Press

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