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Material Type: Artigo
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A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanomaBhatia, Shailender ; Pavlick, Anna C. ; Boasberg, Peter ; Thompson, John A. ; Mulligan, George ; Pickard, Michael D. ; Faessel, Hélène ; Dezube, Bruce J. ; Hamid, OmidInvestigational new drugs, 2016-08, Vol.34 (4), p.439-449 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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Test-retest reproducibility of cerebral adenosine A 2A receptor quantification using [ 11 C]preladenantToyohara, Jun ; Sakata, Muneyuki ; Wagatsuma, Kei ; Tago, Tetsuro ; Ishibashi, Kenji ; Ishii, Kenji ; Elsinga, Philip ; Ishiwata, KiichiAnnals of nuclear medicine, 2022-01, Vol.36 (1), p.15 [Periódico revisado por pares]JapanTexto completo disponível |
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3 |
Material Type: Artigo
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A recombinant fungal photolyase autonomously enters human cell nuclei to fix UV-induced DNA lesionsBao, Yuting ; Fang, WeiguoBiotechnology letters, 2024-06, Vol.46 (3), p.459-467 [Periódico revisado por pares]Dordrecht: Springer NetherlandsTexto completo disponível |
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4 |
Material Type: Artigo
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Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemiaGiles, Francis J. ; Yin, Ophelia Q. P. ; Sallas, William M. ; le Coutre, Philipp D. ; Woodman, Richard C. ; Ottmann, Oliver G. ; Baccarani, Michele ; Kantarjian, Hagop M.European journal of clinical pharmacology, 2013-04, Vol.69 (4), p.813-823 [Periódico revisado por pares]Berlin/Heidelberg: Springer-VerlagTexto completo disponível |
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Material Type: Artigo
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The effect of food on the pharmacokinetics of oral ibrutinib in healthy participants and patients with chronic lymphocytic leukemiade Jong, Jan ; Sukbuntherng, Juthamas ; Skee, Donna ; Murphy, Joe ; O’Brien, Susan ; Byrd, John C. ; James, Danelle ; Hellemans, Peter ; Loury, David J. ; Jiao, Juhui ; Chauhan, Vijay ; Mannaert, ErikCancer chemotherapy and pharmacology, 2015-05, Vol.75 (5), p.907-916 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Synthesis and Pharmacological Evaluation of Novel Triazole-Pyrimidine Hybrids as Potential Neuroprotective and Anti-neuroinflammatory AgentsManzoor, Shoaib ; Almarghalani, Daniyah A. ; James, Antonisamy William ; Raza, Md Kausar ; Kausar, Tasneem ; Nayeem, Shahid M. ; Hoda, Nasimul ; Shah, Zahoor A.Pharmaceutical research, 2023-01, Vol.40 (1), p.167-185 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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Preclinical activity and a pilot phase I study of pacritinib, an oral JAK2/FLT3 inhibitor, and chemotherapy in FLT3-ITD-positive AMLJeon, Jae Yoon ; Zhao, Qiuhong ; Buelow, Daelynn R. ; Phelps, Mitch ; Walker, Alison R. ; Mims, Alice S. ; Vasu, Sumithira ; Behbehani, Gregory ; Blachly, James ; Blum, William ; Klisovic, Rebecca B. ; Byrd, John C. ; Garzon, Ramiro ; Baker, Sharyn D. ; Bhatnagar, BhavanaInvestigational new drugs, 2020-04, Vol.38 (2), p.340-349 [Periódico revisado por pares]New York: Springer USTexto completo disponível |
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Material Type: Artigo
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Molecularly targeted therapies for p53-mutant cancersZhao, Dekuang ; Tahaney, William M. ; Mazumdar, Abhijit ; Savage, Michelle I. ; Brown, Powel H.Cellular and molecular life sciences : CMLS, 2017-11, Vol.74 (22), p.4171-4187 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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9 |
Material Type: Artigo
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Population pharmacokinetic model of ibrutinib, a Bruton tyrosine kinase inhibitor, in patients with B cell malignanciesMarostica, Eleonora ; Sukbuntherng, Juthamas ; Loury, David ; de Jong, Jan ; de Trixhe, Xavier Woot ; Vermeulen, An ; De Nicolao, Giuseppe ; O’Brien, Susan ; Byrd, John C. ; Advani, Ranjana ; McGreivy, Jesse ; Poggesi, ItaloCancer chemotherapy and pharmacology, 2015-01, Vol.75 (1), p.111-121 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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10 |
Material Type: Artigo
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Phase I trial of copanlisib, a selective PI3K inhibitor, in combination with cetuximab in patients with recurrent and/or metastatic head and neck squamous cell carcinomaMarret, Grégoire ; Isambert, Nicolas ; Rezai, Keyvan ; Gal, Jocelyn ; Saada-Bouzid, Esma ; Rolland, Frédéric ; Chausson, Maggy ; Borcoman, Edith ; Alt, Marie ; Klijanienko, Jerzy ; Vansteene, Damien ; Guigay, Joël ; Kamal, Maud ; Bièche, Ivan ; Le Tourneau, ChristopheInvestigational new drugs, 2021-12, Vol.39 (6), p.1641-1648 [Periódico revisado por pares]New York: Springer USTexto completo disponível |