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Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial
Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial
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Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial

Camidge, D Ross ; Kim, Hye Ryun ; Ahn, Myung-Ju ; Yang, James C H ; Han, Ji-Youn ; Hochmair, Maximilian J ; Lee, Ki Hyeong ; Delmonte, Angelo ; García Campelo, Maria Rosario ; Kim, Dong-Wan ; Griesinger, Frank ; Felip, Enriqueta ; Califano, Raffaele ; Spira, Alexander ; Gettinger, Scott N ; Tiseo, Marcello ; Lin, Huamao M ; Gupta, Neeraj ; Hanley, Michael J ; Ni, Quanhong ; Zhang, Pingkuan ; Popat, Sanjay

Journal of clinical oncology, 2020-11, Vol.38 (31), p.3592-3603 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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2
Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study
Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study
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Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study

Nogova, Lucia ; Sequist, Lecia V ; Perez Garcia, Jose Manuel ; Andre, Fabrice ; Delord, Jean-Pierre ; Hidalgo, Manuel ; Schellens, Jan H M ; Cassier, Philippe A ; Camidge, D Ross ; Schuler, Martin ; Vaishampayan, Ulka ; Burris, Howard ; Tian, G Gary ; Campone, Mario ; Wainberg, Zev A ; Lim, Wan-Teck ; LoRusso, Patricia ; Shapiro, Geoffrey I ; Parker, Katie ; Chen, Xueying ; Choudhury, Somesh ; Ringeisen, Francois ; Graus-Porta, Diana ; Porter, Dale ; Isaacs, Randi ; Buettner, Reinhard ; Wolf, Jürgen

Journal of clinical oncology, 2017-01, Vol.35 (2), p.157-165 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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3
Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold
Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold
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Functional Pyrazolo[1,5- a ]pyrimidines: Current Approaches in Synthetic Transformations and Uses As an Antitumor Scaffold

Arias-Gómez, Andres ; Godoy, Andrés ; Portilla, Jaime

Molecules (Basel, Switzerland), 2021-05, Vol.26 (9), p.2708 [Periódico revisado por pares]

Switzerland: MDPI AG

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4
Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5- a ]pyrimidines
Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5- a ]pyrimidines
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Biological Evaluation and Molecular Docking with In Silico Physicochemical, Pharmacokinetic and Toxicity Prediction of Pyrazolo[1,5- a ]pyrimidines

Naglah, Ahmed M ; Askar, Ahmed A ; Hassan, Ashraf S ; Khatab, Tamer K ; Al-Omar, Mohamed A ; Bhat, Mashooq A

Molecules (Basel, Switzerland), 2020-03, Vol.25 (6), p.1431 [Periódico revisado por pares]

Switzerland: MDPI AG

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5
Risdiplam in Type 1 Spinal Muscular Atrophy
Risdiplam in Type 1 Spinal Muscular Atrophy
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Risdiplam in Type 1 Spinal Muscular Atrophy

Baranello, Giovanni ; Darras, Basil T ; Day, John W ; Deconinck, Nicolas ; Klein, Andrea ; Masson, Riccardo ; Mercuri, Eugenio ; Rose, Kristy ; El-Khairi, Muna ; Gerber, Marianne ; Gorni, Ksenija ; Khwaja, Omar ; Kletzl, Heidemarie ; Scalco, Renata S ; Seabrook, Timothy ; Fontoura, Paulo ; Servais, Laurent

The New England journal of medicine, 2021-03, Vol.384 (10), p.915-923 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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6
Futibatinib, an Irreversible FGFR1-4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF / FGFR Aberrations: A Phase I Dose-Expansion Study
Futibatinib, an Irreversible FGFR1-4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF / FGFR Aberrations: A Phase I Dose-Expansion Study
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Futibatinib, an Irreversible FGFR1-4 Inhibitor, in Patients with Advanced Solid Tumors Harboring FGF / FGFR Aberrations: A Phase I Dose-Expansion Study

Meric-Bernstam, Funda ; Bahleda, Rastislav ; Hierro, Cinta ; Sanson, Marc ; Bridgewater, John ; Arkenau, Hendrik-Tobias ; Tran, Ben ; Kelley, Robin Kate ; Park, Joon Oh ; Javle, Milind ; He, Yaohua ; Benhadji, Karim A ; Goyal, Lipika

Cancer discovery, 2022-02, Vol.12 (2), p.402-415

United States: American Association for Cancer Research

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7
Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia

Byrd, John C ; Furman, Richard R ; Coutre, Steven E ; Flinn, Ian W ; Burger, Jan A ; Blum, Kristie A ; Grant, Barbara ; Sharman, Jeff P ; Coleman, Morton ; Wierda, William G ; Jones, Jeffrey A ; Zhao, Weiqiang ; Heerema, Nyla A ; Johnson, Amy J ; Sukbuntherng, Juthamas ; Chang, Betty Y ; Clow, Fong ; Hedrick, Eric ; Buggy, Joseph J ; James, Danelle F ; O'Brien, Susan

The New England journal of medicine, 2013-07, Vol.369 (1), p.32-42 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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8
Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations
Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations
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Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations

Pal, Sumanta K ; Rosenberg, Jonathan E ; Hoffman-Censits, Jean H ; Berger, Raanan ; Quinn, David I ; Galsky, Matthew D ; Wolf, Juergen ; Dittrich, Christian ; Keam, Bhumsuk ; Delord, Jean-Pierre ; Schellens, Jan H M ; Gravis, Gwenaelle ; Medioni, Jacques ; Maroto, Pablo ; Sriuranpong, Virote ; Charoentum, Chaiyut ; Burris, Howard A ; Grünwald, Viktor ; Petrylak, Daniel ; Vaishampayan, Ulka ; Gez, Eliahu ; De Giorgi, Ugo ; Lee, Jae-Lyun ; Voortman, Jens ; Gupta, Sumati ; Sharma, Sunil ; Mortazavi, Amir ; Vaughn, David J ; Isaacs, Randi ; Parker, Katie ; Chen, Xueying ; Yu, Kun ; Porter, Dale ; Graus Porta, Diana ; Bajorin, Dean F

Cancer discovery, 2018-07, Vol.8 (7), p.812-821

United States

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9
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study
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Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

Larson, Richard A. ; Druker, Brian J. ; Guilhot, Francois ; O'Brien, Stephen G. ; Riviere, Gilles J. ; Krahnke, Tillmann ; Gathmann, Insa ; Wang, Yanfeng

Blood, 2008-04, Vol.111 (8), p.4022-4028 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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10
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis
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Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis

Ytterberg, Steven R ; Bhatt, Deepak L ; Mikuls, Ted R ; Koch, Gary G ; Fleischmann, Roy ; Rivas, Jose L ; Germino, Rebecca ; Menon, Sujatha ; Sun, Yanhui ; Wang, Cunshan ; Shapiro, Andrea B ; Kanik, Keith S ; Connell, Carol A

The New England journal of medicine, 2022-01, Vol.386 (4), p.316-326 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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