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Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)
Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)
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Safety and Antitumor Activity of the Multitargeted Pan-TRK, ROS1, and ALK Inhibitor Entrectinib: Combined Results from Two Phase I Trials (ALKA-372-001 and STARTRK-1)

Drilon, Alexander ; Siena, Salvatore ; Ou, Sai-Hong Ignatius ; Patel, Manish ; Ahn, Myung Ju ; Lee, Jeeyun ; Bauer, Todd M ; Farago, Anna F ; Wheler, Jennifer J ; Liu, Stephen V ; Doebele, Robert ; Giannetta, Laura ; Cerea, Giulio ; Marrapese, Giovanna ; Schirru, Michele ; Amatu, Alessio ; Bencardino, Katia ; Palmeri, Laura ; Sartore-Bianchi, Andrea ; Vanzulli, Angelo ; Cresta, Sara ; Damian, Silvia ; Duca, Matteo ; Ardini, Elena ; Li, Gang ; Christiansen, Jason ; Kowalski, Karey ; Johnson, Ann D ; Patel, Rupal ; Luo, David ; Chow-Maneval, Edna ; Hornby, Zachary ; Multani, Pratik S ; Shaw, Alice T ; De Braud, Filippo G

Cancer discovery, 2017-04, Vol.7 (4), p.400-409

United States

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2
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children
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Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

Drilon, Alexander ; Laetsch, Theodore W ; Kummar, Shivaani ; DuBois, Steven G ; Lassen, Ulrik N ; Demetri, George D ; Nathenson, Michael ; Doebele, Robert C ; Farago, Anna F ; Pappo, Alberto S ; Turpin, Brian ; Dowlati, Afshin ; Brose, Marcia S ; Mascarenhas, Leo ; Federman, Noah ; Berlin, Jordan ; El-Deiry, Wafik S ; Baik, Christina ; Deeken, John ; Boni, Valentina ; Nagasubramanian, Ramamoorthy ; Taylor, Matthew ; Rudzinski, Erin R ; Meric-Bernstam, Funda ; Sohal, Davendra P.S ; Ma, Patrick C ; Raez, Luis E ; Hechtman, Jaclyn F ; Benayed, Ryma ; Ladanyi, Marc ; Tuch, Brian B ; Ebata, Kevin ; Cruickshank, Scott ; Ku, Nora C ; Cox, Michael C ; Hawkins, Douglas S ; Hong, David S ; Hyman, David M

The New England journal of medicine, 2018-02, Vol.378 (8), p.731-739 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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3
Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small-Cell Lung Cancer: Results From the Phase II TRINITY Study
Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small-Cell Lung Cancer: Results From the Phase II TRINITY Study
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Efficacy and Safety of Rovalpituzumab Tesirine in Third-Line and Beyond Patients with DLL3-Expressing, Relapsed/Refractory Small-Cell Lung Cancer: Results From the Phase II TRINITY Study

Morgensztern, Daniel ; Besse, Benjamin ; Greillier, Laurent ; Santana-Davila, Rafael ; Ready, Neal ; Hann, Christine L ; Glisson, Bonnie S ; Farago, Anna F ; Dowlati, Afshin ; Rudin, Charles M ; Le Moulec, Sylvestre ; Lally, Satwant ; Yalamanchili, Sreeni ; Wolf, Jürgen ; Govindan, Ramaswamy ; Carbone, David P

Clinical cancer research, 2019-12, Vol.25 (23), p.6958-6966 [Periódico revisado por pares]

United States

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4
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective Analysis
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective Analysis
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EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer: A Retrospective Analysis

Gainor, Justin F ; Shaw, Alice T ; Sequist, Lecia V ; Fu, Xiujun ; Azzoli, Christopher G ; Piotrowska, Zofia ; Huynh, Tiffany G ; Zhao, Ling ; Fulton, Linnea ; Schultz, Katherine R ; Howe, Emily ; Farago, Anna F ; Sullivan, Ryan J ; Stone, James R ; Digumarthy, Subba ; Moran, Teresa ; Hata, Aaron N ; Yagi, Yukako ; Yeap, Beow Y ; Engelman, Jeffrey A ; Mino-Kenudson, Mari

Clinical cancer research, 2016-09, Vol.22 (18), p.4585-4593 [Periódico revisado por pares]

United States

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5
Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials
Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials
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Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials

Hong, David S ; DuBois, Steven G ; Kummar, Shivaani ; Farago, Anna F ; Albert, Catherine M ; Rohrberg, Kristoffer S ; van Tilburg, Cornelis M ; Nagasubramanian, Ramamoorthy ; Berlin, Jordan D ; Federman, Noah ; Mascarenhas, Leo ; Geoerger, Birgit ; Dowlati, Afshin ; Pappo, Alberto S ; Bielack, Stefan ; Doz, François ; McDermott, Ray ; Patel, Jyoti D ; Schilder, Russell J ; Tahara, Makoto ; Pfister, Stefan M ; Witt, Olaf ; Ladanyi, Marc ; Rudzinski, Erin R ; Nanda, Shivani ; Childs, Barrett H ; Laetsch, Theodore W ; Hyman, David M ; Drilon, Alexander

The lancet oncology, 2020-04, Vol.21 (4), p.531-540 [Periódico revisado por pares]

England: Elsevier Ltd

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6
EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes
EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes
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EGFR-Mutant Adenocarcinomas That Transform to Small-Cell Lung Cancer and Other Neuroendocrine Carcinomas: Clinical Outcomes

Marcoux, Nicolas ; Gettinger, Scott N ; O'Kane, Grainne ; Arbour, Kathryn C ; Neal, Joel W ; Husain, Hatim ; Evans, Tracey L ; Brahmer, Julie R ; Muzikansky, Alona ; Bonomi, Philip D ; Del Prete, Salvatore ; Wurtz, Anna ; Farago, Anna F ; Dias-Santagata, Dora ; Mino-Kenudson, Mari ; Reckamp, Karen L ; Yu, Helena A ; Wakelee, Heather A ; Shepherd, Frances A ; Piotrowska, Zofia ; Sequist, Lecia V

Journal of clinical oncology, 2019-02, Vol.37 (4), p.278-285 [Periódico revisado por pares]

United States: American Society of Clinical Oncology

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7
Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study
Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study
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Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study

Hong, D.S. ; Bauer, T.M. ; Lee, J.J. ; Dowlati, A. ; Brose, M.S. ; Farago, A.F. ; Taylor, M. ; Shaw, A.T. ; Montez, S. ; Meric-Bernstam, F. ; Smith, S. ; Tuch, B.B. ; Ebata, K. ; Cruickshank, S. ; Cox, M.C. ; Burris, H.A. ; Doebele, R.C.

Annals of oncology, 2019-02, Vol.30 (2), p.325-331 [Periódico revisado por pares]

England: Elsevier Ltd

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8
Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer
Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer
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Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Locally Advanced or Metastatic ROS1 Fusion-Positive Non-Small-Cell Lung Cancer

Dziadziuszko, Rafal ; Krebs, Matthew G ; De Braud, Filippo ; Siena, Salvatore ; Drilon, Alexander ; Doebele, Robert C ; Patel, Manish R ; Cho, Byoung Chul ; Liu, Stephen V ; Ahn, Myung-Ju ; Chiu, Chao-Hua ; Farago, Anna F ; Lin, Chia-Chi ; Karapetis, Christos S ; Li, Yu-Chung ; Day, Bann-Mo ; Chen, David ; Wilson, Timothy R ; Barlesi, Fabrice

Journal of clinical oncology, 2021-04, Vol.39 (11), p.1253-1263 [Periódico revisado por pares]

United States: Wolters Kluwer Health

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9
Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial
Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial
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Combination lurbinectedin and doxorubicin versus physician's choice of chemotherapy in patients with relapsed small-cell lung cancer (ATLANTIS): a multicentre, randomised, open-label, phase 3 trial

Aix, Santiago Ponce ; Ciuleanu, Tudor Eliade ; Navarro, Alejandro ; Cousin, Sophie ; Bonanno, Laura ; Smit, Egbert F ; Chiappori, Alberto ; Olmedo, Maria Eugenia ; Horvath, Ildiko ; Grohé, Christian ; Farago, Anna F ; López-Vilariño, José Antonio ; Cullell-Young, Martin ; Nieto, Antonio ; Vasco, Noelia ; Gómez, Javier ; Kahatt, Carmen ; Zeaiter, Ali ; Carcereny, Enric ; Roubec, Jaromir ; Syrigos, Konstantinos ; Lo, Gregory ; Barneto, Isidoro ; Pope, Anthony ; Sánchez, Amparo ; Kattan, Joseph ; Zarogoulidis, Konstantinos ; Waller, Cornelius F ; Bischoff, Helge ; Juan-Vidal, Oscar ; Reinmuth, Niels ; Dómine, Manuel ; Paz-Ares, Luis

The lancet respiratory medicine, 2023-01, Vol.11 (1), p.74-86 [Periódico revisado por pares]

England: Elsevier Ltd

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10
Brigatinib in Patients With Alectinib-Refractory ALK-Positive NSCLC
Brigatinib in Patients With Alectinib-Refractory ALK-Positive NSCLC
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Brigatinib in Patients With Alectinib-Refractory ALK-Positive NSCLC

Lin, Jessica J. ; Zhu, Viola W. ; Schoenfeld, Adam J. ; Yeap, Beow Y. ; Saxena, Ashish ; Ferris, Lorin A. ; Dagogo-Jack, Ibiayi ; Farago, Anna F. ; Taber, Angela ; Traynor, Anne ; Menon, Smitha ; Gainor, Justin F. ; Lennerz, Jochen K. ; Plodkowski, Andrew J. ; Digumarthy, Subba R. ; Ou, Sai-Hong Ignatius ; Shaw, Alice T. ; Riely, Gregory J.

Journal of thoracic oncology, 2018-10, Vol.13 (10), p.1530-1538 [Periódico revisado por pares]

United States: Elsevier Inc

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