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Material Type: Artigo
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Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR -Mutant NSCLCLe, Xiuning ; Puri, Sonam ; Negrao, Marcelo V ; Nilsson, Monique B ; Robichaux, Jacqulyne ; Boyle, Theresa ; Hicks, J Kevin ; Lovinger, Katherine L ; Roarty, Emily ; Rinsurongkawong, Waree ; Tang, Ming ; Sun, Huiying ; Elamin, Yasir ; Lacerda, Lara C ; Lewis, Jeff ; Roth, Jack A ; Swisher, Stephen G ; Lee, J Jack ; William, Jr, William N ; Glisson, Bonnie S ; Zhang, Jianjun ; Papadimitrakopoulou, Vassiliki A ; Gray, Jhanelle E ; Heymach, John VClinical cancer research, 2018-12, Vol.24 (24), p.6195-6203 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT studySicklick, Jason K ; Kato, Shumei ; Okamura, Ryosuke ; Schwaederle, Maria ; Hahn, Michael E ; Williams, Casey B ; De, Pradip ; Krie, Amy ; Piccioni, David E ; Miller, Vincent A ; Ross, Jeffrey S ; Benson, Adam ; Webster, Jennifer ; Stephens, Philip J ; Lee, J Jack ; Fanta, Paul T ; Lippman, Scott M ; Leyland-Jones, Brian ; Kurzrock, RazelleNature medicine, 2019-05, Vol.25 (5), p.744-750 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancerKamerkar, Sushrut ; LeBleu, Valerie S ; Sugimoto, Hikaru ; Yang, Sujuan ; Ruivo, Carolina F ; Melo, Sonia A ; Lee, J Jack ; Kalluri, RaghuNature (London), 2017-06, Vol.546 (7659), p.498-503 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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A utility‐based Bayesian optimal interval (U‐BOIN) phase I/II design to identify the optimal biological dose for targeted and immune therapiesZhou, Yanhong ; Lee, J. Jack ; Yuan, YingStatistics in medicine, 2019-12, Vol.38 (28), p.5299-5316 [Periódico revisado por pares]England: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Dose Escalation Methods in Phase I Cancer Clinical TrialsLe Tourneau, Christophe ; Lee, J. Jack ; Siu, Lillian L.JNCI : Journal of the National Cancer Institute, 2009-05, Vol.101 (10), p.708-720 [Periódico revisado por pares]Cary, NC: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Bayesian clinical trials in actionJack Lee, J. ; Chu, Caleb T.Statistics in medicine, 2012-11, Vol.31 (25), p.2955-2972 [Periódico revisado por pares]Chichester, UK: John Wiley & Sons, LtdTexto completo disponível |
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Material Type: Artigo
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Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical TrialsSchwaederle, Maria ; Zhao, Melissa ; Lee, J Jack ; Eggermont, Alexander M ; Schilsky, Richard L ; Mendelsohn, John ; Lazar, Vladimir ; Kurzrock, RazelleJournal of clinical oncology, 2015-11, Vol.33 (32), p.3817-3825 [Periódico revisado por pares]United States: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic TargetsFerrarotto, Renata ; Mitani, Yoshitsugu ; McGrail, Daniel J ; Li, Kaiyi ; Karpinets, Tatiana V ; Bell, Diana ; Frank, Steven J ; Song, Xingzhi ; Kupferman, Michael E ; Liu, Bin ; Lee, J Jack ; Glisson, Bonnie S ; Zhang, Jianhua ; Aster, Jon C ; Lin, Shiaw-Yih ; Futreal, P Andrew ; Heymach, John V ; El-Naggar, Adel KClinical cancer research, 2021-02, Vol.27 (3), p.852-864 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trialRodon, Jordi ; Soria, Jean-Charles ; Berger, Raanan ; Miller, Wilson H ; Rubin, Eitan ; Kugel, Aleksandra ; Tsimberidou, Apostolia ; Saintigny, Pierre ; Ackerstein, Aliza ; Braña, Irene ; Loriot, Yohann ; Afshar, Mohammad ; Miller, Vincent ; Wunder, Fanny ; Bresson, Catherine ; Martini, Jean-François ; Raynaud, Jacques ; Mendelsohn, John ; Batist, Gerald ; Onn, Amir ; Tabernero, Josep ; Schilsky, Richard L ; Lazar, Vladimir ; Lee, J Jack ; Kurzrock, RazelleNature Medicine, 2019-05, Vol.25 (5), p.751-758 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1Li, Hongzhong ; Xiao, Yi ; Li, Qin ; Yao, Jun ; Yuan, Xiangliang ; Zhang, Yuan ; Yin, Xuedong ; Saito, Yohei ; Fan, Huihui ; Li, Ping ; Kuo, Wen-Ling ; Halpin, Angela ; Gibbons, Don L. ; Yagita, Hideo ; Zhao, Zhongming ; Pang, Da ; Ren, Guosheng ; Yee, Cassian ; Lee, J. Jack ; Yu, DihuaCancer cell, 2022-01, Vol.40 (1), p.36-52.e9 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |