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Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile
Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile
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Acalabrutinib (ACP-196): A Covalent Bruton Tyrosine Kinase Inhibitor with a Differentiated Selectivity and In Vivo Potency Profile

Barf, Tjeerd ; Covey, Todd ; Izumi, Raquel ; van de Kar, Bas ; Gulrajani, Michael ; van Lith, Bart ; van Hoek, Maaike ; de Zwart, Edwin ; Mittag, Diana ; Demont, Dennis ; Verkaik, Saskia ; Krantz, Fanny ; Pearson, Paul G ; Ulrich, Roger ; Kaptein, Allard

The Journal of pharmacology and experimental therapeutics, 2017-11, Vol.363 (2), p.240-252 [Periódico revisado por pares]

United States

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2
Protease inhibitors targeting coronavirus and filovirus entry
Protease inhibitors targeting coronavirus and filovirus entry
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Protease inhibitors targeting coronavirus and filovirus entry

Zhou, Yanchen ; Vedantham, Punitha ; Lu, Kai ; Agudelo, Juliet ; Carrion, Ricardo ; Nunneley, Jerritt W. ; Barnard, Dale ; Pöhlmann, Stefan ; McKerrow, James H. ; Renslo, Adam R. ; Simmons, Graham

Antiviral research, 2015-04, Vol.116, p.76-84 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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3
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
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Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma

Li, Zhong-Jie ; Dai, Hui-Qi ; Huang, Xiao-Wei ; Feng, Ji ; Deng, Jing-Huan ; Wang, Zi-Xuan ; Yang, Xiao-Mei ; Liu, Yu-Jia ; Wu, Yong ; Chen, Pan-Hong ; Shi, Huan ; Wang, Ji-Gang ; Zhou, Jing ; Lu, Guo-Dong

Acta pharmacologica Sinica, 2021-02, Vol.42 (2), p.301-310 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris
Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris
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Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris

Kordalewska, Milena ; Lee, Annie ; Park, Steven ; Berrio, Indira ; Chowdhary, Anuradha ; Zhao, Yanan ; Perlin, David S

Antimicrobial agents and chemotherapy, 2018-06, Vol.62 (6) [Periódico revisado por pares]

United States: American Society for Microbiology

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5
Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics
Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics
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Cell type-specific and common characteristics of exosomes derived from mouse cell lines: Yield, physicochemical properties, and pharmacokinetics

Charoenviriyakul, Chonlada ; Takahashi, Yuki ; Morishita, Masaki ; Matsumoto, Akihiro ; Nishikawa, Makiya ; Takakura, Yoshinobu

European journal of pharmaceutical sciences, 2017-01, Vol.96, p.316-322 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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6
The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
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The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro

Song, Junke ; Zhang, Li ; Xu, Yanfeng ; Yang, Dezhi ; Zhang, Li ; Yang, Shiying ; Zhang, Wen ; Wang, Jinhua ; Tian, Shuo ; Yang, Shengqian ; Yuan, Tianyi ; Liu, Ailin ; Lv, Qi ; Li, Fengdi ; Liu, Hongqi ; Hou, Biyu ; Peng, Xiaozhong ; Lu, Yang ; Du, Guanhua

Biochemical pharmacology, 2021-01, Vol.183, p.114302-114302, Article 114302 [Periódico revisado por pares]

England: Elsevier Inc

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7
Geniposide, from Gardenia jasminoides Ellis, inhibits the inflammatory response in the primary mouse macrophages and mouse models
Geniposide, from Gardenia jasminoides Ellis, inhibits the inflammatory response in the primary mouse macrophages and mouse models
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Geniposide, from Gardenia jasminoides Ellis, inhibits the inflammatory response in the primary mouse macrophages and mouse models

Fu, Yunhe ; Liu, Bo ; Liu, Jinhua ; Liu, Zhicheng ; Liang, Dejie ; Li, Fengyang ; Li, Depeng ; Cao, Yongguo ; Zhang, Xichen ; Zhang, Naisheng ; Yang, Zhengtao

International immunopharmacology, 2012-12, Vol.14 (4), p.792-798 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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8
Discovery of Novel Pyrrolo[2,3‑d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors
Discovery of Novel Pyrrolo[2,3‑d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors
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Discovery of Novel Pyrrolo[2,3‑d]pyrimidine-based Derivatives as Potent JAK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors

Liang, Xuewu ; Tang, Shuai ; Liu, Xuyi ; Liu, Yingluo ; Xu, Qifu ; Wang, Xiaomin ; Saidahmatov, Abdusaid ; Li, Chunpu ; Wang, Jiang ; Zhou, Yu ; Zhang, Yingjie ; Geng, Meiyu ; Huang, Min ; Liu, Hong

Journal of medicinal chemistry, 2022-01, Vol.65 (2), p.1243-1264 [Periódico revisado por pares]

United States: American Chemical Society

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9
Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents
Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents
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Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents

Pang, Yanqing ; An, Baijiao ; Lou, Lanlan ; Zhang, Junsheng ; Yan, Jun ; Huang, Ling ; Li, Xingshu ; Yin, Sheng

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7300-7314 [Periódico revisado por pares]

United States: American Chemical Society

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10
Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors
Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors
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Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors

Thakur, Ashish ; Tawa, Gregory J ; Henderson, Mark J ; Danchik, Carina ; Liu, Suiyang ; Shah, Pranav ; Wang, Amy Q ; Dunn, Garrett ; Kabir, Md ; Padilha, Elias C ; Xu, Xin ; Simeonov, Anton ; Kharbanda, Surender ; Stone, Richard ; Grewal, Gurmit

Journal of medicinal chemistry, 2020-04, Vol.63 (8), p.4256-4292 [Periódico revisado por pares]

United States: American Chemical Society

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