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1 |
Material Type: Artigo
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Kidney-Targeted Birt-Hogg-Dubé Gene Inactivation in a Mouse Model: Erk1/2 and Akt-mTOR Activation, Cell Hyperproliferation, and Polycystic KidneysBaba, Masaya ; Furihata, Mutsuo ; Hong, Seung-Beom ; Tessarollo, Lino ; Haines, Diana C. ; Southon, Eileen ; Patel, Vishal ; Igarashi, Peter ; Alvord, W. Gregory ; Leighty, Robert ; Yao, Masahiro ; Bernardo, Marcelino ; Ileva, Lilia ; Choyke, Peter ; Warren, Michelle B. ; Zbar, Berton ; Linehan, W. Marston ; Schmidt, Laura S.JNCI : Journal of the National Cancer Institute, 2008-01, Vol.100 (2), p.140-154 [Periódico revisado por pares]Cary, NC: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stressVerfaillie, T ; Rubio, N ; Garg, A D ; Bultynck, G ; Rizzuto, R ; Decuypere, J-P ; Piette, J ; Linehan, C ; Gupta, S ; Samali, A ; Agostinis, PCell death and differentiation, 2012-11, Vol.19 (11), p.1880-1891 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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MAIT cells are imprinted by the microbiota in early life and promote tissue repairConstantinides, Michael G ; Link, Verena M ; Tamoutounour, Samira ; Wong, Andrea C ; Perez-Chaparro, P Juliana ; Han, Seong-Ji ; Chen, Y Erin ; Li, Kelin ; Farhat, Sepideh ; Weckel, Antonin ; Krishnamurthy, Siddharth R ; Vujkovic-Cvijin, Ivan ; Linehan, Jonathan L ; Bouladoux, Nicolas ; Merrill, E Dean ; Roy, Sobhan ; Cua, Daniel J ; Adams, Erin J ; Bhandoola, Avinash ; Scharschmidt, Tiffany C ; Aubé, Jeffrey ; Fischbach, Michael A ; Belkaid, YasmineScience (American Association for the Advancement of Science), 2019-10, Vol.366 (6464) [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue RepairLinehan, Jonathan L. ; Harrison, Oliver J. ; Han, Seong-Ji ; Byrd, Allyson L. ; Vujkovic-Cvijin, Ivan ; Villarino, Alejandro V. ; Sen, Shurjo K. ; Shaik, Jahangheer ; Smelkinson, Margery ; Tamoutounour, Samira ; Collins, Nicholas ; Bouladoux, Nicolas ; Dzutsev, Amiran ; Rosshart, Stephan P. ; Arbuckle, Jesse H. ; Wang, Chyung-Ru ; Kristie, Thomas M. ; Rehermann, Barbara ; Trinchieri, Giorgio ; Brenchley, Jason M. ; O’Shea, John J. ; Belkaid, YasmineCell, 2018-02, Vol.172 (4), p.784-796.e18 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Therapeutic Targeting of TFE3/IRS-1/PI3K/mTOR Axis in Translocation Renal Cell CarcinomaDamayanti, Nur P ; Budka, Justin A ; Khella, Heba W Z ; Ferris, Mary W ; Ku, Sheng Yu ; Kauffman, Eric ; Wood, Anthony C ; Ahmed, Khunsha ; Chintala, Venkata Nithinsai ; Adelaiye-Ogala, Remi ; Elbanna, May ; Orillion, Ashley ; Chintala, Sreenivasulu ; Kao, Chinghai ; Linehan, W Marston ; Yousef, George M ; Hollenhorst, Peter C ; Pili, RobertoClinical cancer research, 2018-12, Vol.24 (23), p.5977-5989 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancerXie, Han ; Valera, Vladimir A ; Merino, Maria J ; Amato, Angela M ; Signoretti, Sabina ; Linehan, William M ; Sukhatme, Vikas P ; Seth, PankajMolecular cancer therapeutics, 2009-03, Vol.8 (3), p.626-635 [Periódico revisado por pares]United States: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Ionic immune suppression within the tumour microenvironment limits T cell effector functionEil, Robert ; Vodnala, Suman K ; Clever, David ; Klebanoff, Christopher A ; Sukumar, Madhusudhanan ; Pan, Jenny H ; Palmer, Douglas C ; Gros, Alena ; Yamamoto, Tori N ; Patel, Shashank J ; Guittard, Geoffrey C ; Yu, Zhiya ; Carbonaro, Valentina ; Okkenhaug, Klaus ; Schrump, David S ; Linehan, W Marston ; Roychoudhuri, Rahul ; Restifo, Nicholas PNature (London), 2016-09, Vol.537 (7621), p.539-543 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Robust antigen specific th17 T cell response to group A Streptococcus is dependent on IL-6 and intranasal route of infectionDileepan, Thamotharampillai ; Linehan, Jonathan L ; Moon, James J ; Pepper, Marion ; Jenkins, Marc K ; Cleary, Patrick P Gilmore, Michael S.PLoS pathogens, 2011-09, Vol.7 (9), p.e1002252-e1002252 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Novel mutations of the MET proto-oncogene in papillary renal carcinomasSCHMIDT, L ; JUNKER, K ; VOCKE, C ; BROWN, J. A ; JENKINS, R ; RICHARD, S ; BERGERHEIM, U ; GERRARD, B ; DEAN, M ; LINEHAN, W. M ; ZBAR, B ; NAKAIGAWA, N ; KINJERSKI, T ; WEIRICH, G ; MILLER, M ; LUBENSKY, I ; NEUMANN, H. P. H ; BRAUCH, H ; DECKER, JOncogene, 1999-04, Vol.18 (14), p.2343-2350 [Periódico revisado por pares]Basingstoke: Nature PublishingTexto completo disponível |
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Material Type: Artigo
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Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPKGoncharova, Elena A. ; Goncharov, Dmitry A. ; James, Melane L. ; Atochina-Vasserman, Elena N. ; Stepanova, Victoria ; Hong, Seung-Beom ; Li, Hua ; Gonzales, Linda ; Baba, Masaya ; Linehan, W. Marston ; Gow, Andrew J. ; Margulies, Susan ; Guttentag, Susan ; Schmidt, Laura S. ; Krymskaya, Vera P.Cell reports (Cambridge), 2014-04, Vol.7 (2), p.412-423 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |