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1
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

Sun, Chong ; Wang, Liqin ; Huang, Sidong ; Heynen, Guus J J E ; Prahallad, Anirudh ; Robert, Caroline ; Haanen, John ; Blank, Christian ; Wesseling, Jelle ; Willems, Stefan M ; Zecchin, Davide ; Hobor, Sebastijan ; Bajpe, Prashanth K ; Lieftink, Cor ; Mateus, Christina ; Vagner, Stephan ; Grernrum, Wipawadee ; Hofland, Ingrid ; Schlicker, Andreas ; Wessels, Lodewyk F A ; Beijersbergen, Roderick L ; Bardelli, Alberto ; Di Nicolantonio, Federica ; Eggermont, Alexander M M ; Bernards, Rene

Nature (London), 2014-04, Vol.508 (7494), p.118-122 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer
Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer
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Single-cell profiling guided combinatorial immunotherapy for fast-evolving CDK4/6 inhibitor-resistant HER2-positive breast cancer

Wang, Qingfei ; Guldner, Ian H ; Golomb, Samantha M ; Sun, Longhua ; Harris, Jack A ; Lu, Xin ; Zhang, Siyuan

Nature communications, 2019-08, Vol.10 (1), p.3817-12, Article 3817 [Periódico revisado por pares]

England: Nature Publishing Group

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3
A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations
A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations
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A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations

Zhou, L ; Zhang, Y ; Chen, S ; Kmieciak, M ; Leng, Y ; Lin, H ; Rizzo, K A ; Dumur, C I ; Ferreira-Gonzalez, A ; Dai, Y ; Grant, S

Leukemia, 2015-04, Vol.29 (4), p.807-818 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Shi, Hubing ; Sazegar, Hooman ; Nazarian, Ramin ; Chodon, Thinle ; Lee, Hane ; Sosman, Jeffrey A ; Lo, Roger S ; Koya, Richard C ; Lee, Mi-Kyung ; Attar, Narsis ; Kong, Xiangju ; Nelson, Stanley F ; Ribas, Antoni ; Chen, Zugen ; McArthur, Grant ; Wang, Qi

Nature (London), 2010-12, Vol.468 (7326), p.973-977 [Periódico revisado por pares]

London: Nature Publishing Group

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5
A novel retinoblastoma therapy from genomic and epigenetic analyses
A novel retinoblastoma therapy from genomic and epigenetic analyses
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A novel retinoblastoma therapy from genomic and epigenetic analyses

JINGHUI ZHANG ; BENAVENTE, Claudia A ; BRENNAN, Rachel ; RUSCH, Michael ; MANNING, Amity L ; JING MA ; EASTON, John ; SHURTLEFF, Sheila ; MULLIGHAN, Charles ; POUNDS, Stanley ; MUKATIRA, Suraj ; GUPTA, Pankaj ; MCEVOY, Justina ; NEALE, Geoff ; ZHAO, David ; LU, Charles ; FULTON, Robert S ; FULTON, Lucinda L ; XIN HONG ; DOOLING, David J ; OCHOA, Kerri ; NAEVE, Clayton ; DYSON, Nicholas J ; FLORES-OTERO, Jacqueline ; MARDIS, Elaine R ; BAHRAMI, Armita ; ELLISON, David ; WILSON, Richard K ; DOWNING, James R ; DYER, Michael A ; LI DING ; XIANG CHEN ; ULYANOV, Anatoly ; GANG WU ; WILSON, Matthew ; JIANMIN WANG

Nature (London), 2012-01, Vol.481 (7381), p.329-334 [Periódico revisado por pares]

London: Nature Publishing Group

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6
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
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Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer

ZHENFENG ZHANG ; JAE CHEOL LEE ; YUN JUNG CHOI ; CHOI, Chang-Min ; KIM, Sang-We ; SE JIN JANG ; YOUNG SOO PARK ; WOO SUNG KIM ; DAE HO LEE ; LEE, Jung-Shin ; MILLER, Vincent A ; ARCILA, Maria ; LUPING LIN ; LADANYI, Marc ; MOONSAMY, Philicia ; SAWYERS, Charles ; BOGGON, Titus J ; MA, Patrick C ; COSTA, Carlota ; TARON, Miquel ; ROSELL, Rafael ; HALMOS, Balazs ; BIVONA, Treverg ; OLIVAS, Victor ; AU, Valerie ; LAFRAMBOISE, Thomas ; ABDEL-RAHMAN, Mohamed ; XIAOQI WANG ; LEVINE, Alan D ; JIN KYUNG RHO

Nature genetics, 2012-08, Vol.44 (8), p.852-860 [Periódico revisado por pares]

New York, NY: Nature Publishing Group

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7
Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI
Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI
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Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

Weng, Chien-Hui ; Chen, Li-Yu ; Lin, Yu-Chin ; Shih, Jin-Yuan ; Lin, Yun-Chieh ; Tseng, Ruo-Yu ; Chiu, An-Chieh ; Yeh, Yu-Hsuan ; Liu, Chi ; Lin, Yi-Ting ; Fang, Jim-Min ; Chen, Ching-Chow

Oncogene, 2019-01, Vol.38 (4), p.455-468 [Periódico revisado por pares]

England: Nature Publishing Group

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8
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

Nold-Petry, Claudia A ; Lo, Camden Y ; Rudloff, Ina ; Elgass, Kirstin D ; Li, Suzhao ; Gantier, Michael P ; Lotz-Havla, Amelie S ; Gersting, Søren W ; Cho, Steven X ; Lao, Jason C ; Ellisdon, Andrew M ; Rotter, Björn ; Azam, Tania ; Mangan, Niamh E ; Rossello, Fernando J ; Whisstock, James C ; Bufler, Philip ; Garlanda, Cecilia ; Mantovani, Alberto ; Dinarello, Charles A ; Nold, Marcel F

Nature immunology, 2015-04, Vol.16 (4), p.354-365 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
Verteporfin inhibits growth of human glioma in vitro without light activation
Verteporfin inhibits growth of human glioma in vitro without light activation
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Verteporfin inhibits growth of human glioma in vitro without light activation

Al-Moujahed, Ahmad ; Brodowska, Katarzyna ; Stryjewski, Tomasz P ; Efstathiou, Nikolaos E ; Vasilikos, Ioannis ; Cichy, Joanna ; Miller, Joan W ; Gragoudas, Evangelos ; Vavvas, Demetrios G

Scientific reports, 2017-08, Vol.7 (1), p.7602-8, Article 7602 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia
Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia
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Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia

Park, I-K ; Mundy-Bosse, B ; Whitman, S P ; Zhang, X ; Warner, S L ; Bearss, D J ; Blum, W ; Marcucci, G ; Caligiuri, M A

Leukemia, 2015-12, Vol.29 (12), p.2382-2389 [Periódico revisado por pares]

England: Nature Publishing Group

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