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Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial
Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial
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Efficacy of boceprevir, an NS3 protease inhibitor, in combination with peginterferon alfa-2b and ribavirin in treatment-naive patients with genotype 1 hepatitis C infection (SPRINT-1): an open-label, randomised, multicentre phase 2 trial

Kwo, Paul Y, Dr ; Lawitz, Eric J, MD ; McCone, Jonathan, MD ; Schiff, Eugene R, Prof ; Vierling, John M, Prof ; Pound, David, MD ; Davis, Mitchell N, DO ; Galati, Joseph S, MD ; Gordon, Stuart C, MD ; Ravendhran, Natarajan, MD ; Rossaro, Lorenzo, Prof ; Anderson, Frank H, MD ; Jacobson, Ira M, Prof ; Rubin, Raymond, MD ; Koury, Kenneth, PhD ; Pedicone, Lisa D, PhD ; Brass, Clifford A, MD ; Chaudhri, Eirum, MD ; Albrecht, Janice K, PhD

The Lancet (British edition), 2010-08, Vol.376 (9742), p.705-716 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment‐naïve patients
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment‐naïve patients
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Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment‐naïve patients

Kuntzen, Thomas ; Timm, Joerg ; Berical, Andrew ; Lennon, Niall ; Berlin, Aaron M. ; Young, Sarah K. ; Lee, Bongshin ; Heckerman, David ; Carlson, Jonathan ; Reyor, Laura L. ; Kleyman, Marianna ; McMahon, Cory M. ; Birch, Christopher ; Schulze zur Wiesch, Julian ; Ledlie, Timothy ; Koehrsen, Michael ; Kodira, Chinnappa ; Roberts, Andrew D. ; Lauer, Georg M. ; Rosen, Hugo R. ; Bihl, Florian ; Cerny, Andreas ; Spengler, Ulrich ; Liu, Zhimin ; Kim, Arthur Y. ; Xing, Yanming ; Schneidewind, Arne ; Madey, Margaret A. ; Fleckenstein, Jaquelyn F. ; Park, Vicki M. ; Galagan, James E. ; Nusbaum, Chad ; Walker, Bruce D. ; Lake‐Bakaar, Gerond V. ; Daar, Eric S. ; Jacobson, Ira M. ; Gomperts, Edward D. ; Edlin, Brian R. ; Donfield, Sharyne M. ; Chung, Raymond T. ; Talal, Andrew H. ; Marion, Tony ; Birren, Bruce W. ; Henn, Matthew R. ; Allen, Todd M.

Hepatology (Baltimore, Md.), 2008-12, Vol.48 (6), p.1769-1778 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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3
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients
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Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients

Susser, Simone ; Welsch, Christoph ; Wang, Yalan ; Zettler, Markus ; Domingues, Francisco S. ; Karey, Ursula ; Hughes, Eric ; Ralston, Robert ; Tong, Xiao ; Herrmann, Eva ; Zeuzem, Stefan ; Sarrazin, Christoph

Hepatology (Baltimore, Md.), 2009-12, Vol.50 (6), p.1709-1718 [Periódico revisado por pares]

Hoboken: Wiley Subscription Services, Inc., A Wiley Company

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4
Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection
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Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

Njoroge, F. George ; Chen, Kevin X ; Shih, Neng-Yang ; Piwinski, John J

Accounts of chemical research, 2008-01, Vol.41 (1), p.50-59 [Periódico revisado por pares]

United States: American Chemical Society

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5
New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals
New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals
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New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals

Seden, Kay ; Back, David ; Khoo, Saye

Journal of antimicrobial chemotherapy, 2010-06, Vol.65 (6), p.1079-1085 [Periódico revisado por pares]

Oxford: Oxford University Press

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6
The Gap Junction Modifier, GAP-134 [(2S,4R)-1-(2-Aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic Acid], Improves Conduction and Reduces Atrial Fibrillation/Flutter in the Canine Sterile Pericarditis Model
The Gap Junction Modifier, GAP-134 [(2S,4R)-1-(2-Aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic Acid], Improves Conduction and Reduces Atrial Fibrillation/Flutter in the Canine Sterile Pericarditis Model
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The Gap Junction Modifier, GAP-134 [(2S,4R)-1-(2-Aminoacetyl)-4-benzamido-pyrrolidine-2-carboxylic Acid], Improves Conduction and Reduces Atrial Fibrillation/Flutter in the Canine Sterile Pericarditis Model

Rossman, Eric I ; Liu, Kun ; Morgan, Gwen A ; Swillo, Robert E ; Krueger, Julie A ; Gardell, Stephen J ; Butera, John ; Gruver, Matthew ; Kantrowitz, Joel ; Feldman, Hal S ; Petersen, Jørgen S ; Haugan, Ketil ; Hennan, James K

The Journal of pharmacology and experimental therapeutics, 2009-06, Vol.329 (3), p.1127-1133 [Periódico revisado por pares]

United States: American Society for Pharmacology and Experimental Therapeutics

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7
Boceprevir, an NS3 Protease Inhibitor of HCV
Boceprevir, an NS3 Protease Inhibitor of HCV
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Boceprevir, an NS3 Protease Inhibitor of HCV

Berman, Kenneth, MD ; Kwo, Paul Y., MD

Clinics in liver disease, 2009-08, Vol.13 (3), p.429-439 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice
Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice
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Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice

Messina, Sonia ; Bitto, Alessandra ; Aguennouz, M'hammed ; Minutoli, Letteria ; Monici, Maria C. ; Altavilla, Domenica ; Squadrito, Francesco ; Vita, Giuseppe

Experimental neurology, 2006-03, Vol.198 (1), p.234-241 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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9
Excitement grows for potential revolution in hepatitis C virus treatment
Excitement grows for potential revolution in hepatitis C virus treatment
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Excitement grows for potential revolution in hepatitis C virus treatment

Opar, Alisa

Nature reviews. Drug discovery, 2010-07, Vol.9 (7), p.501-503 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats
Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats
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Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats

Hagar, Hanan H. ; El Medany, Azza ; El Eter, Eman ; Arafa, Maha

European journal of pharmacology, 2007-01, Vol.554 (1), p.69-77 [Periódico revisado por pares]

Amsterdam: Elsevier B.V

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