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1
Serine-linked PARP1 auto-modification controls PARP inhibitor response
Serine-linked PARP1 auto-modification controls PARP inhibitor response
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Serine-linked PARP1 auto-modification controls PARP inhibitor response

Prokhorova, Evgeniia ; Zobel, Florian ; Smith, Rebecca ; Zentout, Siham ; Gibbs-Seymour, Ian ; Schützenhofer, Kira ; Peters, Alessandra ; Groslambert, Joséphine ; Zorzini, Valentina ; Agnew, Thomas ; Brognard, John ; Nielsen, Michael L ; Ahel, Dragana ; Huet, Sébastien ; Suskiewicz, Marcin J ; Ahel, Ivan

Nature communications, 2021-07, Vol.12 (1), p.4055-4055, Article 4055 [Periódico revisado por pares]

England: Nature Publishing Group

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2
PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
PARP2 mediates branched poly ADP-ribosylation in response to DNA damage
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PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

Chen, Qian ; Kassab, Muzaffer Ahmad ; Dantzer, Françoise ; Yu, Xiaochun

Nature communications, 2018-08, Vol.9 (1), p.3233-13, Article 3233 [Periódico revisado por pares]

England: Nature Publishing Group

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3
HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications
HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications
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HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications

Langelier, Marie-France ; Billur, Ramya ; Sverzhinsky, Aleksandr ; Black, Ben E ; Pascal, John M

Nature communications, 2021-11, Vol.12 (1), p.6675-6675, Article 6675 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy
Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy
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Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

Krüger, Annika ; Bürkle, Alexander ; Hauser, Karin ; Mangerich, Aswin

Nature communications, 2020-05, Vol.11 (1), p.2174-15, Article 2174 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma
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Defective homologous recombination DNA repair as therapeutic target in advanced chordoma

Gröschel, Stefan ; Hübschmann, Daniel ; Raimondi, Francesco ; Horak, Peter ; Warsow, Gregor ; Fröhlich, Martina ; Klink, Barbara ; Gieldon, Laura ; Hutter, Barbara ; Kleinheinz, Kortine ; Bonekamp, David ; Marschal, Oliver ; Chudasama, Priya ; Mika, Jagoda ; Groth, Marie ; Uhrig, Sebastian ; Krämer, Stephen ; Heining, Christoph ; Heilig, Christoph E ; Richter, Daniela ; Reisinger, Eva ; Pfütze, Katrin ; Eils, Roland ; Wolf, Stephan ; von Kalle, Christof ; Brandts, Christian ; Scholl, Claudia ; Weichert, Wilko ; Richter, Stephan ; Bauer, Sebastian ; Penzel, Roland ; Schröck, Evelin ; Stenzinger, Albrecht ; Schlenk, Richard F ; Brors, Benedikt ; Russell, Robert B ; Glimm, Hanno ; Schlesner, Matthias ; Fröhling, Stefan

Nature communications, 2019-04, Vol.10 (1), p.1635-9, Article 1635 [Periódico revisado por pares]

England: Nature Publishing Group

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6
A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity
A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity
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A genetic screen using the PiggyBac transposon in haploid cells identifies Parp1 as a mediator of olaparib toxicity

Pettitt, Stephen J ; Rehman, Farah L ; Bajrami, Ilirjana ; Brough, Rachel ; Wallberg, Fredrik ; Kozarewa, Iwanka ; Fenwick, Kerry ; Assiotis, Ioannis ; Chen, Lina ; Campbell, James ; Lord, Christopher J ; Ashworth, Alan Boutros, Michael

PloS one, 2013-04, Vol.8 (4), p.e61520 [Periódico revisado por pares]

United States: Public Library of Science

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7
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
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PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer

Chabanon, Roman M ; Muirhead, Gareth ; Krastev, Dragomir B ; Adam, Julien ; Morel, Daphné ; Garrido, Marlène ; Lamb, Andrew ; Hénon, Clémence ; Dorvault, Nicolas ; Rouanne, Mathieu ; Marlow, Rebecca ; Bajrami, Ilirjana ; Cardeñosa, Marta Llorca ; Konde, Asha ; Besse, Benjamin ; Ashworth, Alan ; Pettitt, Stephen J ; Haider, Syed ; Marabelle, Aurélien ; Tutt, Andrew Nj ; Soria, Jean-Charles ; Lord, Christopher J ; Postel-Vinay, Sophie

The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1211-1228 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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8
PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
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PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation

Ronson, George E ; Piberger, Ann Liza ; Higgs, Martin R ; Olsen, Anna L ; Stewart, Grant S ; McHugh, Peter J ; Petermann, Eva ; Lakin, Nicholas D

Nature communications, 2018-02, Vol.9 (1), p.746-12, Article 746 [Periódico revisado por pares]

England: Nature Publishing Group

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9
HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones
HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones
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HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones

Sun, Fa-Hui ; Zhao, Peng ; Zhang, Nan ; Kong, Lu-Lu ; Wong, Catherine C L ; Yun, Cai-Hong

Nature communications, 2021-02, Vol.12 (1), p.1028-10, Article 1028 [Periódico revisado por pares]

England: Nature Publishing Group

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10
PARP inhibitor resistance: the underlying mechanisms and clinical implications
PARP inhibitor resistance: the underlying mechanisms and clinical implications
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PARP inhibitor resistance: the underlying mechanisms and clinical implications

Li, He ; Liu, Zhao-Yi ; Wu, Nayiyuan ; Chen, Yong-Chang ; Cheng, Quan ; Wang, Jing

Molecular cancer, 2020-06, Vol.19 (1), p.107-107, Article 107 [Periódico revisado por pares]

England: BioMed Central Ltd

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