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1 |
Material Type: Artigo
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Targeting DNA damage response pathways in cancerGroelly, Florian J ; Fawkes, Matthew ; Dagg, Rebecca A ; Blackford, Andrew N ; Tarsounas, MadalenaNature reviews. Cancer, 2023-02, Vol.23 (2), p.78-94 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Serine-linked PARP1 auto-modification controls PARP inhibitor responseProkhorova, Evgeniia ; Zobel, Florian ; Smith, Rebecca ; Zentout, Siham ; Gibbs-Seymour, Ian ; Schützenhofer, Kira ; Peters, Alessandra ; Groslambert, Joséphine ; Zorzini, Valentina ; Agnew, Thomas ; Brognard, John ; Nielsen, Michael L ; Ahel, Dragana ; Huet, Sébastien ; Suskiewicz, Marcin J ; Ahel, IvanNature communications, 2021-07, Vol.12 (1), p.4055-4055, Article 4055 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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PARP inhibitors: Synthetic lethality in the clinicLord, Christopher J. ; Ashworth, AlanScience (American Association for the Advancement of Science), 2017-03, Vol.355 (6330), p.1152-1158 [Periódico revisado por pares]United States: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesionsZimmermann, Michal ; Murina, Olga ; Reijns, Martin A M ; Agathanggelou, Angelo ; Challis, Rachel ; Tarnauskaitė, Žygimantė ; Muir, Morwenna ; Fluteau, Adeline ; Aregger, Michael ; McEwan, Andrea ; Yuan, Wei ; Clarke, Matthew ; Lambros, Maryou B ; Paneesha, Shankara ; Moss, Paul ; Chandrashekhar, Megha ; Angers, Stephane ; Moffat, Jason ; Brunton, Valerie G ; Hart, Traver ; de Bono, Johann ; Stankovic, Tatjana ; Jackson, Andrew P ; Durocher, DanielNature (London), 2018-07, Vol.559 (7713), p.285-289 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastomaColicchia, V ; Petroni, M ; Guarguaglini, G ; Sardina, F ; Sahún-Roncero, M ; Carbonari, M ; Ricci, B ; Heil, C ; Capalbo, C ; Belardinilli, F ; Coppa, A ; Peruzzi, G ; Screpanti, I ; Lavia, P ; Gulino, A ; Giannini, GOncogene, 2017-08, Vol.36 (33), p.4682-4691 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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PARP mediated DNA damage response, genomic stability and immune responsesZong, Chunyan ; Zhu, Tianyu ; He, Jie ; Huang, Rui ; Jia, Renbing ; Shen, JianfengInternational journal of cancer, 2022-06, Vol.150 (11), p.1745-1759 [Periódico revisado por pares]Hoboken, USA: John Wiley & Sons, IncTexto completo disponível |
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Material Type: Artigo
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The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the artDe Vos, Mike ; Schreiber, Valérie ; Dantzer, FrançoiseBiochem Pharmacol, 2012-07, Vol.84 (2), p.137-146 [Periódico revisado por pares]England: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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CDK12 regulates DNA repair genes by suppressing intronic polyadenylationDubbury, Sara J ; Boutz, Paul L ; Sharp, Phillip ANature (London), 2018-12, Vol.564 (7734), p.141-145 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structural basis for allosteric PARP-1 retention on DNA breaksZandarashvili, Levani ; Langelier, Marie-France ; Velagapudi, Uday Kiran ; Hancock, Mark A ; Steffen, Jamin D ; Billur, Ramya ; Hannan, Zain M ; Wicks, Andrew J ; Krastev, Dragomir B ; Pettitt, Stephen J ; Lord, Christopher J ; Talele, Tanaji T ; Pascal, John M ; Black, Ben EScience (American Association for the Advancement of Science), 2020-04, Vol.368 (6486) [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Joining the PARty: PARP Regulation of KDM5A during DNA Repair (and Transcription?)Sanchez, Anthony ; Buck‐Koehntop, Bethany A. ; Miller, Kyle M.BioEssays, 2022-07, Vol.44 (7), p.e2200015-n/a [Periódico revisado por pares]United States: Wiley Subscription Services, IncTexto completo disponível |