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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
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CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

Zimmermann, Michal ; Murina, Olga ; Reijns, Martin A M ; Agathanggelou, Angelo ; Challis, Rachel ; Tarnauskaitė, Žygimantė ; Muir, Morwenna ; Fluteau, Adeline ; Aregger, Michael ; McEwan, Andrea ; Yuan, Wei ; Clarke, Matthew ; Lambros, Maryou B ; Paneesha, Shankara ; Moss, Paul ; Chandrashekhar, Megha ; Angers, Stephane ; Moffat, Jason ; Brunton, Valerie G ; Hart, Traver ; de Bono, Johann ; Stankovic, Tatjana ; Jackson, Andrew P ; Durocher, Daniel

Nature (London), 2018-07, Vol.559 (7713), p.285-289 [Periódico revisado por pares]

England: Nature Publishing Group

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2
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
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CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

Dubbury, Sara J ; Boutz, Paul L ; Sharp, Phillip A

Nature (London), 2018-12, Vol.564 (7734), p.141-145 [Periódico revisado por pares]

England: Nature Publishing Group

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3
High speed of fork progression induces DNA replication stress and genomic instability
High speed of fork progression induces DNA replication stress and genomic instability
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High speed of fork progression induces DNA replication stress and genomic instability

Maya-Mendoza, Apolinar ; Moudry, Pavel ; Merchut-Maya, Joanna Maria ; Lee, MyungHee ; Strauss, Robert ; Bartek, Jiri

Nature (London), 2018-07, Vol.559 (7713), p.279-284 [Periódico revisado por pares]

England: Nature Publishing Group

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4
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
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PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer

Chabanon, Roman M ; Muirhead, Gareth ; Krastev, Dragomir B ; Adam, Julien ; Morel, Daphné ; Garrido, Marlène ; Lamb, Andrew ; Hénon, Clémence ; Dorvault, Nicolas ; Rouanne, Mathieu ; Marlow, Rebecca ; Bajrami, Ilirjana ; Cardeñosa, Marta Llorca ; Konde, Asha ; Besse, Benjamin ; Ashworth, Alan ; Pettitt, Stephen J ; Haider, Syed ; Marabelle, Aurélien ; Tutt, Andrew Nj ; Soria, Jean-Charles ; Lord, Christopher J ; Postel-Vinay, Sophie

The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1211-1228 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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5
PARP inhibitor resistance: the underlying mechanisms and clinical implications
PARP inhibitor resistance: the underlying mechanisms and clinical implications
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PARP inhibitor resistance: the underlying mechanisms and clinical implications

Li, He ; Liu, Zhao-Yi ; Wu, Nayiyuan ; Chen, Yong-Chang ; Cheng, Quan ; Wang, Jing

Molecular cancer, 2020-06, Vol.19 (1), p.107-107, Article 107 [Periódico revisado por pares]

England: BioMed Central Ltd

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6
Niraparib: First Global Approval
Niraparib: First Global Approval
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Niraparib: First Global Approval

Scott, Lesley J.

Drugs (New York, N.Y.), 2017-06, Vol.77 (9), p.1029-1034 [Periódico revisado por pares]

Cham: Springer International Publishing

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7
Proteomics approaches to identify mono-(ADP-ribosyl)ated and poly(ADP-ribosyl)ated proteins
Proteomics approaches to identify mono-(ADP-ribosyl)ated and poly(ADP-ribosyl)ated proteins
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Proteomics approaches to identify mono-(ADP-ribosyl)ated and poly(ADP-ribosyl)ated proteins

Vivelo, Christina A. ; Leung, Anthony K. L.

Proteomics (Weinheim), 2015-01, Vol.15 (2-3), p.203-217 [Periódico revisado por pares]

Germany: Blackwell Publishing Ltd

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8
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
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Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

Liu, Haipeng ; Zhang, Haiping ; Wu, Xiangyang ; Ma, Dapeng ; Wu, Juehui ; Wang, Lin ; Jiang, Yan ; Fei, Yiyan ; Zhu, Chenggang ; Tan, Rong ; Jungblut, Peter ; Pei, Gang ; Dorhoi, Anca ; Yan, Qiaoling ; Zhang, Fan ; Zheng, Ruijuan ; Liu, Siyu ; Liang, Haijiao ; Liu, Zhonghua ; Yang, Hua ; Chen, Jianxia ; Wang, Peng ; Tang, Tianqi ; Peng, Wenxia ; Hu, Zhangsen ; Xu, Zhu ; Huang, Xiaochen ; Wang, Jie ; Li, Haohao ; Zhou, Yilong ; Liu, Feng ; Yan, Dapeng ; Kaufmann, Stefan H E ; Chen, Chang ; Mao, Zhiyong ; Ge, Baoxue

Nature (London), 2018-11, Vol.563 (7729), p.131-136 [Periódico revisado por pares]

England: Nature Publishing Group

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9
PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols
PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols
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PARP-1-Associated Pathological Processes: Inhibition by Natural Polyphenols

Maluchenko, Natalya V ; Feofanov, Alexey V ; Studitsky, Vasily M

International journal of molecular sciences, 2021-10, Vol.22 (21), p.11441 [Periódico revisado por pares]

Switzerland: MDPI AG

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10
Trypanosoma cruzi PARP is enriched in the nucleolus and is present in a thread connecting nuclei during mitosis
Trypanosoma cruzi PARP is enriched in the nucleolus and is present in a thread connecting nuclei during mitosis
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Trypanosoma cruzi PARP is enriched in the nucleolus and is present in a thread connecting nuclei during mitosis

Kevorkian, María Laura ; Vilchez Larrea, Salomé C ; Fernández Villamil, Silvia H Prigent, Claude

PloS one, 2022-12, Vol.17 (12), p.e0267329-e0267329 [Periódico revisado por pares]

United States: Public Library of Science

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