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Targeting DNA damage response pathways in cancer
Targeting DNA damage response pathways in cancer
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Targeting DNA damage response pathways in cancer

Groelly, Florian J ; Fawkes, Matthew ; Dagg, Rebecca A ; Blackford, Andrew N ; Tarsounas, Madalena

Nature reviews. Cancer, 2023-02, Vol.23 (2), p.78-94 [Periódico revisado por pares]

England: Nature Publishing Group

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Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function
Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function
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Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function

Gui, Bin ; Gui, Fu ; Takai, Tomoaki ; Feng, Chao ; Bai, Xiao ; Fazli, Ladan ; Dong, Xuesen ; Liu, Shuai ; Zhang, Xiaofeng ; Zhang, Wei ; Kibel, Adam S. ; Jia, Li

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (29), p.14573-14582 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
PARP inhibitors: Synthetic lethality in the clinic
PARP inhibitors: Synthetic lethality in the clinic
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PARP inhibitors: Synthetic lethality in the clinic

Lord, Christopher J. ; Ashworth, Alan

Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6330), p.1152-1158 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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4
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma
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PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma

Colicchia, V ; Petroni, M ; Guarguaglini, G ; Sardina, F ; Sahún-Roncero, M ; Carbonari, M ; Ricci, B ; Heil, C ; Capalbo, C ; Belardinilli, F ; Coppa, A ; Peruzzi, G ; Screpanti, I ; Lavia, P ; Gulino, A ; Giannini, G

Oncogene, 2017-08, Vol.36 (33), p.4682-4691 [Periódico revisado por pares]

England: Nature Publishing Group

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5
PARP mediated DNA damage response, genomic stability and immune responses
PARP mediated DNA damage response, genomic stability and immune responses
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PARP mediated DNA damage response, genomic stability and immune responses

Zong, Chunyan ; Zhu, Tianyu ; He, Jie ; Huang, Rui ; Jia, Renbing ; Shen, Jianfeng

International journal of cancer, 2022-06, Vol.150 (11), p.1745-1759 [Periódico revisado por pares]

Hoboken, USA: John Wiley & Sons, Inc

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6
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
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CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

Dubbury, Sara J ; Boutz, Paul L ; Sharp, Phillip A

Nature (London), 2018-12, Vol.564 (7734), p.141-145 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Structural basis for allosteric PARP-1 retention on DNA breaks
Structural basis for allosteric PARP-1 retention on DNA breaks
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Structural basis for allosteric PARP-1 retention on DNA breaks

Zandarashvili, Levani ; Langelier, Marie-France ; Velagapudi, Uday Kiran ; Hancock, Mark A ; Steffen, Jamin D ; Billur, Ramya ; Hannan, Zain M ; Wicks, Andrew J ; Krastev, Dragomir B ; Pettitt, Stephen J ; Lord, Christopher J ; Talele, Tanaji T ; Pascal, John M ; Black, Ben E

Science (American Association for the Advancement of Science), 2020-04, Vol.368 (6486) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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8
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer
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PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer

Chabanon, Roman M ; Muirhead, Gareth ; Krastev, Dragomir B ; Adam, Julien ; Morel, Daphné ; Garrido, Marlène ; Lamb, Andrew ; Hénon, Clémence ; Dorvault, Nicolas ; Rouanne, Mathieu ; Marlow, Rebecca ; Bajrami, Ilirjana ; Cardeñosa, Marta Llorca ; Konde, Asha ; Besse, Benjamin ; Ashworth, Alan ; Pettitt, Stephen J ; Haider, Syed ; Marabelle, Aurélien ; Tutt, Andrew Nj ; Soria, Jean-Charles ; Lord, Christopher J ; Postel-Vinay, Sophie

The Journal of clinical investigation, 2019-03, Vol.129 (3), p.1211-1228 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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9
PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside
PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside
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PARP inhibitors in breast cancer: Bringing synthetic lethality to the bedside

Turk, Anita A. ; Wisinski, Kari B.

Cancer, 2018-06, Vol.124 (12), p.2498-2506 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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10
Regulation of ALT-associated homology-directed repair by polyADP-ribosylation
Regulation of ALT-associated homology-directed repair by polyADP-ribosylation
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Regulation of ALT-associated homology-directed repair by polyADP-ribosylation

Hoang, Song My ; Kaminski, Nicole ; Bhargava, Ragini ; Barroso-González, Jonathan ; Lynskey, Michelle L ; García-Expósito, Laura ; Roncaioli, Justin L ; Wondisford, Anne R ; Wallace, Callen T ; Watkins, Simon C ; James, Dominic I ; Waddell, Ian D ; Ogilvie, Donald ; Smith, Kate M ; da Veiga Leprevost, Felipe ; Mellacharevu, Dattatreya ; Nesvizhskii, Alexey I ; Li, Jianfeng ; Ray-Gallet, Dominique ; Sobol, Robert W ; Almouzni, Genevieve ; O'Sullivan, Roderick J

Nature structural & molecular biology, 2020-12, Vol.27 (12), p.1152-1164 [Periódico revisado por pares]

United States: Nature Publishing Group

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