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Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious
Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious
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Structure-Based Design of Mdm2/Mdmx-p53 Inhibitors Gets Serious

Popowicz, Grzegorz M ; Dömling, Alexander ; Holak, Tad A

Angewandte Chemie (International ed.), 2011-03, Vol.50 (12), p.2680-2688 [Periódico revisado por pares]

Weinheim: Wiley-VCH Verlag

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2
Development of the Inhibitors that Target the PD-1/PD-L1 Interaction-A Brief Look at Progress on Small Molecules, Peptides and Macrocycles
Development of the Inhibitors that Target the PD-1/PD-L1 Interaction-A Brief Look at Progress on Small Molecules, Peptides and Macrocycles
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Development of the Inhibitors that Target the PD-1/PD-L1 Interaction-A Brief Look at Progress on Small Molecules, Peptides and Macrocycles

Guzik, Katarzyna ; Tomala, Marcin ; Muszak, Damian ; Konieczny, Magdalena ; Hec, Aleksandra ; Błaszkiewicz, Urszula ; Pustuła, Marcin ; Butera, Roberto ; Dömling, Alexander ; Holak, Tad A

Molecules (Basel, Switzerland), 2019-05, Vol.24 (11), p.2071 [Periódico revisado por pares]

Switzerland: MDPI AG

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3
AnchorQuery: Rapid online virtual screening for small‐molecule protein–protein interaction inhibitors
AnchorQuery: Rapid online virtual screening for small‐molecule protein–protein interaction inhibitors
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AnchorQuery: Rapid online virtual screening for small‐molecule protein–protein interaction inhibitors

Koes, David R. ; Dömling, Alexander ; Camacho, Carlos J.

Protein science, 2018-01, Vol.27 (1), p.229-232 [Periódico revisado por pares]

United States: Wiley Subscription Services, Inc

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4
A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables
A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables
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A Systematic Protein Refolding Screen Method using the DGR Approach Reveals that Time and Secondary TSA are Essential Variables

Wang, Yuanze ; van Oosterwijk, Niels ; Ali, Ameena M ; Adawy, Alaa ; Anindya, Atsarina L ; Dömling, Alexander S S ; Groves, Matthew R

Scientific reports, 2017-08, Vol.7 (1), p.9355-10, Article 9355 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
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Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions

Ricardo, Manuel G. ; Ali, Ameena M. ; Plewka, Jacek ; Surmiak, Ewa ; Labuzek, Beata ; Neochoritis, Constantinos G. ; Atmaj, Jack ; Skalniak, Lukasz ; Zhang, Ran ; Holak, Tad A. ; Groves, Matthew ; Rivera, Daniel G. ; Dömling, Alexander

Angewandte Chemie International Edition, 2020-03, Vol.59 (13), p.5235-5241 [Periódico revisado por pares]

Germany: Wiley Subscription Services, Inc

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6
Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery
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Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery

Wang, Zefeng ; Shaabani, Shabnam ; Gao, Xiang ; Ng, Yuen Lam Dora ; Sapozhnikova, Valeriia ; Mertins, Philipp ; Krönke, Jan ; Dömling, Alexander

Nature communications, 2023-12, Vol.14 (1), p.8437-8437, Article 8437 [Periódico revisado por pares]

England: Nature Publishing Group

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7
How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures
How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures
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How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures

Estrada-Ortiz, Natalia ; Neochoritis, Constantinos G. ; Dömling, Alexander

ChemMedChem, 2016-04, Vol.11 (8), p.757-772 [Periódico revisado por pares]

Germany: Blackwell Publishing Ltd

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8
Combining High‐Throughput Synthesis and High‐Throughput Protein Crystallography for Accelerated Hit Identification
Combining High‐Throughput Synthesis and High‐Throughput Protein Crystallography for Accelerated Hit Identification
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Combining High‐Throughput Synthesis and High‐Throughput Protein Crystallography for Accelerated Hit Identification

Sutanto, Fandi ; Shaabani, Shabnam ; Oerlemans, Rick ; Eris, Deniz ; Patil, Pravin ; Hadian, Mojgan ; Wang, Meitian ; Sharpe, May Elizabeth ; Groves, Matthew R. ; Dömling, Alexander

Angewandte Chemie (International ed.), 2021-08, Vol.60 (33), p.18231-18239 [Periódico revisado por pares]

Weinheim: Wiley Subscription Services, Inc

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9
Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery
Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery
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Structures of low molecular weight inhibitors bound to MDMX and MDM2 reveal new approaches for p53-MDMX/MDM2 antagonist drug discovery

Popowicz, Grzegorz M. ; Czarna, Anna ; Wolf, Siglinde ; Wang, Kan ; Wang, Wei ; Dömling, Alexander ; Holak, Tad A.

Cell cycle (Georgetown, Tex.), 2010-03, Vol.9 (6), p.1104-1111 [Periódico revisado por pares]

United States: Taylor & Francis

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10
Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers
Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers
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Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers

Gao, Kai ; Shaabani, Shabnam ; Xu, Ruixue ; Zarganes-Tzitzikas, Tryfon ; Gao, Li ; Ahmadianmoghaddam, Maryam ; Groves, Matthew R ; Dömling, Alexander

RSC medicinal chemistry, 2021-05, Vol.12 (5), p.89-818 [Periódico revisado por pares]

England: RSC

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