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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
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Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Formisano, Luigi ; Lu, Yao ; Servetto, Alberto ; Hanker, Ariella B ; Jansen, Valerie M ; Bauer, Joshua A ; Sudhan, Dhivya R ; Guerrero-Zotano, Angel L ; Croessmann, Sarah ; Guo, Yan ; Ericsson, Paula Gonzalez ; Lee, Kyung-Min ; Nixon, Mellissa J ; Schwarz, Luis J ; Sanders, Melinda E ; Dugger, Teresa C ; Cruz, Marcelo Rocha ; Behdad, Amir ; Cristofanilli, Massimo ; Bardia, Aditya ; O'Shaughnessy, Joyce ; Nagy, Rebecca J ; Lanman, Richard B ; Solovieff, Nadia ; He, Wei ; Miller, Michelle ; Su, Fei ; Shyr, Yu ; Mayer, Ingrid A ; Balko, Justin M ; Arteaga, Carlos L

Nature communications, 2019-03, Vol.10 (1), p.1373-1373, Article 1373 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer
Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer
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Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Jansen, Valerie M ; Bhola, Neil E ; Bauer, Joshua A ; Formisano, Luigi ; Lee, Kyung-Min ; Hutchinson, Katherine E ; Witkiewicz, Agnieszka K ; Moore, Preston D ; Estrada, Mónica Valéria ; Sánchez, Violeta ; Ericsson, Paula G ; Sanders, Melinda E ; Pohlmann, Paula R ; Pishvaian, Michael J ; Riddle, David A ; Dugger, Teresa C ; Wei, Wenyi ; Knudsen, Erik S ; Arteaga, Carlos L

Cancer research (Chicago, Ill.), 2017-05, Vol.77 (9), p.2488-2499 [Periódico revisado por pares]

United States: American Association for Cancer Research, Inc

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3
Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer
Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer
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Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer

Ballinger, Tarah J ; Meier, Jason B ; Jansen, Valerie M

Frontiers in oncology, 2018-08, Vol.8, p.308-308 [Periódico revisado por pares]

Switzerland: Frontiers Media S.A

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4
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
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Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer

Lee, Kyung-Min ; Guerrero-Zotano, Angel L ; Servetto, Alberto ; Sudhan, Dhivya R ; Lin, Chang-Ching ; Formisano, Luigi ; Jansen, Valerie M ; González-Ericsson, Paula ; Sanders, Melinda E ; Stricker, Thomas P ; Raj, Ganesh ; Dean, Kevin M ; Fiolka, Reto ; Cantley, Lewis C ; Hanker, Ariella B ; Arteaga, Carlos L

Nature communications, 2020-10, Vol.11 (1), p.5488-15, Article 5488 [Periódico revisado por pares]

England: Nature Publishing Group

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5
From Biology to Therapy: Improvements of Therapeutic Options in Lung Cancer
From Biology to Therapy: Improvements of Therapeutic Options in Lung Cancer
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From Biology to Therapy: Improvements of Therapeutic Options in Lung Cancer

Formisano, Luigi ; Jansen, Valerie M ; Marciano, Roberta ; Bianco, Roberto

Anti-cancer agents in medicinal chemistry, 2018-01, Vol.18 (9), p.1235-1240 [Periódico revisado por pares]

Netherlands: Bentham Science Publishers Ltd

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6
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
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Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

Miettinen, Teemu P ; Peltier, Julien ; Härtlova, Anetta ; Gierliński, Marek ; Jansen, Valerie M ; Trost, Matthias ; Björklund, Mikael

The EMBO journal, 2018-05, Vol.37 (10), p.n/a [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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7
Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR + /HER2 - Breast Cancer
Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR + /HER2 - Breast Cancer
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Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR + /HER2 - Breast Cancer

Hurvitz, Sara A ; Martin, Miguel ; Press, Michael F ; Chan, David ; Fernandez-Abad, María ; Petru, Edgar ; Rostorfer, Regan ; Guarneri, Valentina ; Huang, Chiun-Sheng ; Barriga, Susana ; Wijayawardana, Sameera ; Brahmachary, Manisha ; Ebert, Philip J ; Hossain, Anwar ; Liu, Jiangang ; Abel, Adam ; Aggarwal, Amit ; Jansen, Valerie M ; Slamon, Dennis J

Clinical cancer research, 2020-02, Vol.26 (3), p.566-580 [Periódico revisado por pares]

United States

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8
Clinical Significance of PIK3CA and ESR1 Mutations in Circulating Tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib plus Fulvestrant
Clinical Significance of PIK3CA and ESR1 Mutations in Circulating Tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib plus Fulvestrant
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Clinical Significance of PIK3CA and ESR1 Mutations in Circulating Tumor DNA: Analysis from the MONARCH 2 Study of Abemaciclib plus Fulvestrant

Tolaney, Sara M ; Toi, Masakazu ; Neven, Patrick ; Sohn, Joohyuk ; Grischke, Eva-Maria ; Llombart-Cussac, Antonio ; Soliman, Hatem ; Wang, Hong ; Wijayawardana, Sameera ; Jansen, Valerie M ; Litchfield, Lacey M ; Sledge, George W

Clinical cancer research, 2022-04, Vol.28 (8), p.1500-1506 [Periódico revisado por pares]

United States

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9
Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
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Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Bhola, Neil E ; Jansen, Valerie M ; Koch, James P ; Li, Hua ; Formisano, Luigi ; Williams, Janice A ; Grandis, Jennifer R ; Arteaga, Carlos L

Cancer research (Chicago, Ill.), 2016-01, Vol.76 (2), p.440-452 [Periódico revisado por pares]

United States

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10
Is There a Future for AKT Inhibitors in the Treatment of Cancer?
Is There a Future for AKT Inhibitors in the Treatment of Cancer?
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Is There a Future for AKT Inhibitors in the Treatment of Cancer?

Jansen, Valerie M ; Mayer, Ingrid A ; Arteaga, Carlos L

Clinical cancer research, 2016-06, Vol.22 (11), p.2599-2601 [Periódico revisado por pares]

United States

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