Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice

Fiorotto, Romina ; Raizner, Aileen ; Morell, Carola M ; Torsello, Barbara ; Scirpo, Roberto ; Fabris, Luca ; Spirli, Carlo ; Strazzabosco, Mario

Netherlands: Elsevier B.V

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Inhibition of IL-1b/STAT3/β-catenin-dependent stimulation of the CXCL10/CXCR3 axis prevents macrophage recruitment and progression of the disease in Pkhd1del4/del4 mice, a model of congenital hepatic fibrosis

Kaffe, E ; Pellegrino, F ; Mariotti, V ; Fabris, L ; Cadamuro, M ; Amenduni, M ; Fiorotto, R ; Strazzabosco, M ; Spirli, C

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P1253 ACTIVATION OF PPAR-γ SIGNALING AS A NOVEL TARGET TO LIMIT NF-κB-DEPENDENT INFLAMMATION IN CYSTIC FIBROSIS BILIARY EPITHELIUM

Scirpo, R ; Fiorotto, R ; Fabris, L ; Strazzabosco, M

Elsevier B.V

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P0220 : JNK signaling activated by platelet-derived growth factor D (PDGF-D) stimulates secretion of vascular endothelial growth factor-C (VEGF-C) by cancer-associated fibroblasts to promote lymphangiogenesis and early metastasization in cholangiocarcinoma

Cadamuro, M ; Vismara, M ; Brivio, S ; Furlanetto, A ; Strazzabosco, M ; Fabris, L

Elsevier B.V

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Inhibition of the CA2+-Inhibited Adenylyl Cyclase 5 Reduces CYST Growth in Mice with Polycystic Liver Disease (ADPKD) Caused by Defective Polycystin-2

Spirli, C ; Mariotti, V ; Villani, A ; Fabris, L ; Fiorotto, R ; Strazzabosco, M

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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models

Olaizola, Paula ; Lee-Law, Pui Yuen ; Fernandez-Barrena, Maite G. ; Alvarez, Laura ; Cadamuro, Massimiliano ; Azkargorta, Mikel ; O’Rourke, Colm J. ; Caballero-Camino, Francisco J. ; Olaizola, Irene ; Macias, Rocio I.R. ; Marin, Jose J.G. ; Serrano-Maciá, Marina ; Martinez-Chantar, Maria L. ; Avila, Matias A. ; Aspichueta, Patricia ; Calvisi, Diego F. ; Evert, Matthias ; Fabris, Luca ; Castro, Rui E. ; Elortza, Felix ; Andersen, Jesper B. ; Bujanda, Luis ; Rodrigues, Pedro M. ; Perugorria, Maria J. ; Banales, Jesus M.

Amsterdam: Elsevier B.V

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P1141 : Post-translational regulation of polycystin 2 (PC2) expression as a novel mechanism of cholangiocyte reaction to biliary damage and repair

Spirli, C ; Villani, A ; Morell, C.M ; Fabris, L ; Fiorotto, R ; Strazzabosco, M

Elsevier B.V

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P0226 : Reduction in sumoylation-dependent S100A4 nuclear import in cholangiocarcinoma by low dose paclitaxel halts tumor invasiveness and hematogenous metastatization by modulating Rho-A and Cdc42 activities

Spagnuolo, G ; Cadamuro, M ; Sambado, L ; Indraccolo, S ; Nardo, G ; Rosato, A ; Novelli, E ; Spirlì, C ; Strazzabosco, M ; Fabris, L

Elsevier B.V

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Inhibition of YAP activation induces cell senescence and autophagy while blocking cell proliferation in cholangiocarcinoma (CCA)

Cadamuro, M. ; Casati, G. ; Stecca, T. ; Brivio, S. ; Milani, C. ; Mariotti, V. ; Kaffe, E. ; Spirli, C. ; Amenduni, M. ; Fiorotto, R. ; Cillo, U. ; Maria, G. ; Fabris, L. ; Strazzabosco, M.

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SAT-151 - Inhibition of YAP activation induces cell senescence and autophagy while blocking cell proliferation in cholangiocarcinoma (CCA)

Cadamuro, M. ; Casati, G. ; Stecca, T. ; Brivio, S. ; Milani, C. ; Mariotti, V. ; Kaffe, E. ; Spirli, C. ; Amenduni, M. ; Fiorotto, R. ; Cillo, U. ; Maria, G. ; Fabris, L. ; Strazzabosco, M.

Elsevier B.V

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