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Refinado por: Base de dados/Biblioteca: DOAJ Directory of Open Access Journals remover assunto: Life Sciences & Biomedicine remover
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1
Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa
Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa
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Nonclinical Safety Evaluation of scAAV8- RLBP1 for Treatment of RLBP1 Retinitis Pigmentosa

MacLachlan, Timothy K ; Milton, Mark N ; Turner, Oliver ; Tukov, Francis ; Choi, Vivian W ; Penraat, Jan ; Delmotte, Marie-Hélène ; Michaut, Lydia ; Jaffee, Bruce D ; Bigelow, Chad E

Molecular therapy. Methods & clinical development, 2018-03, Vol.8 (C), p.105-120 [Periódico revisado por pares]

United States: Elsevier Limited

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2
BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression
BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression
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BRCA1 Effects on the Cell Cycle and the DNA Damage Response Are Linked to Altered Gene Expression

MacLachlan, Timothy K. ; Somasundaram, Kumaravel ; Sgagias, Magda ; Shifman, Yelena ; Muschel, Ruth J. ; Cowan, Kenneth H. ; El-Deiry, Wafik S.

The Journal of biological chemistry, 2000-01, Vol.275 (4), p.2777-2785 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use
Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use
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Challenges and opportunities for the future of monoclonal antibody development: Improving safety assessment and reducing animal use

Sewell, Fiona ; Chapman, Kathryn ; Couch, Jessica ; Dempster, Maggie ; Heidel, Shawn ; Loberg, Lise ; Maier, Curtis ; Maclachlan, Timothy K ; Todd, Marque ; van der Laan, Jan Willem

mAbs, 2017-07, Vol.9 (5), p.742-755 [Periódico revisado por pares]

United States: Taylor & Francis

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4
BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation
BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation
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BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation

Takimoto, Rishu ; MacLachlan, Timothy K. ; Dicker, David T. ; Niitsu, Yoshiro ; Mori, Toshio ; El-Deiry, Wafik S.

Cancer biology & therapy, 2002-03, Vol.1 (2), p.177-186 [Periódico revisado por pares]

United States: Taylor & Francis

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5
Repression of BRCA1 through a Feedback Loop Involving p53
Repression of BRCA1 through a Feedback Loop Involving p53
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Repression of BRCA1 through a Feedback Loop Involving p53

MacLachlan, Timothy K. ; Dash, Bipin C. ; Dicker, David T. ; El-Deiry, Wafik S.

The Journal of biological chemistry, 2000-10, Vol.275 (41), p.31869-31875 [Periódico revisado por pares]

United States: Elsevier Inc

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6
BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit
BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit
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BRCA1 Augments Transcription by the NF-κB Transcription Factor by Binding to the Rel Domain of the p65/RelA Subunit

Benezra, Miriam ; Chevallier, Nathalie ; Morrison, Debra J. ; MacLachlan, Timothy K. ; El-Deiry, Wafik S. ; Licht, Jonathan D.

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26333-26341 [Periódico revisado por pares]

Elsevier Inc

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7
Marine-derived cancer therapeutics making a splash
Marine-derived cancer therapeutics making a splash
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Marine-derived cancer therapeutics making a splash

MacLachlan, Timothy K. ; Pinkas, Jan

Cancer biology & therapy, 2005-08, Vol.4 (8), p.883-884 [Periódico revisado por pares]

United States: Taylor & Francis

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8
A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity
A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity
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A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity

De Luca, Antonio ; MacLachlan, Timothy K. ; Bagella, Luigi ; Dean, Charity ; Howard, Candace M. ; Claudio, Pier Paolo ; Baldi, Alfonso ; Khalili, Kamel ; Giordano, Antonio

The Journal of biological chemistry, 1997-08, Vol.272 (34), p.20971-20974 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Insights into differential endostatin activity
Insights into differential endostatin activity
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Insights into differential endostatin activity

MacLachlan, Timothy K. ; Dhanabal, Mohanraj

Cancer biology & therapy, 2004-11, Vol.3 (11), p.1167-1168 [Periódico revisado por pares]

United States: Taylor & Francis

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10
Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling
Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling
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Insulin-like growth factor factor binding protein-2 is a novel mediator of p53 inhibition of insulin-like growth factor signaling

Grimberg, Adda ; Coleman, Carrie M ; Shi, Zonggao ; Burns, Timothy F ; MacLachlan, Timothy K ; Wang, Wenge ; El-Deiry, Wafik S

Cancer biology & therapy, 2006-10, Vol.5 (10), p.1408-1414 [Periódico revisado por pares]

United States

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