Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients

Woitek, Ramona ; McLean, Mary A ; Ursprung, Stephan ; Rueda, Oscar M ; Manzano Garcia, Raquel ; Locke, Matthew J ; Beer, Lucian ; Baxter, Gabrielle ; Rundo, Leonardo ; Provenzano, Elena ; Kaggie, Joshua ; Patterson, Andrew ; Frary, Amy ; Field-Rayner, Johanna ; Papalouka, Vasiliki ; Kane, Justine ; Benjamin, Arnold J V ; Gill, Andrew B ; Priest, Andrew N ; Lewis, David Y ; Russell, Roslin ; Grimmer, Ashley ; White, Brian ; Latimer-Bowman, Beth ; Patterson, Ilse ; Schiller, Amy ; Carmo, Bruno ; Slough, Rhys ; Lanz, Titus ; Wason, James ; Schulte, Rolf F ; Chin, Suet-Feung ; Graves, Martin J ; Gilbert, Fiona J ; Abraham, Jean E ; Caldas, Carlos ; Brindle, Kevin M ; Sala, Evis ; Gallagher, Ferdia A

United States

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PDX-MI: Minimal Information for Patient-Derived Tumor Xenograft Models

Meehan, Terrence F ; Conte, Nathalie ; Goldstein, Theodore ; Inghirami, Giorgio ; Murakami, Mark A ; Brabetz, Sebastian ; Gu, Zhiping ; Wiser, Jeffrey A ; Dunn, Patrick ; Begley, Dale A ; Krupke, Debra M ; Bertotti, Andrea ; Bruna, Alejandra ; Brush, Matthew H ; Byrne, Annette T ; Caldas, Carlos ; Christie, Amanda L ; Clark, Dominic A ; Dowst, Heidi ; Dry, Jonathan R ; Doroshow, James H ; Duchamp, Olivier ; Evrard, Yvonne A ; Ferretti, Stephane ; Frese, Kristopher K ; Goodwin, Neal C ; Greenawalt, Danielle ; Haendel, Melissa A ; Hermans, Els ; Houghton, Peter J ; Jonkers, Jos ; Kemper, Kristel ; Khor, Tin O ; Lewis, Michael T ; Lloyd, K C Kent ; Mason, Jeremy ; Medico, Enzo ; Neuhauser, Steven B ; Olson, James M ; Peeper, Daniel S ; Rueda, Oscar M ; Seong, Je Kyung ; Trusolino, Livio ; Vinolo, Emilie ; Wechsler-Reya, Robert J ; Weinstock, David M ; Welm, Alana ; Weroha, S John ; Amant, Frédéric ; Pfister, Stefan M ; Kool, Marcel ; Parkinson, Helen ; Butte, Atul J ; Bult, Carol J

United States: American Association for Cancer Research, Inc

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Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification

Pellegrino, Benedetta ; Herencia-Ropero, Andrea ; Llop-Guevara, Alba ; Pedretti, Flaminia ; Moles-Fernández, Alejandro ; Viaplana, Cristina ; Villacampa, Guillermo ; Guzmán, Marta ; Rodríguez, Olga ; Grueso, Judit ; Jiménez, Jose ; Arenas, Enrique J ; Degasperi, Andrea ; Dias, João M L ; Forment, Josep V ; O'Connor, Mark J ; Déas, Olivier ; Cairo, Stefano ; Zhou, Yinghui ; Musolino, Antonino ; Caldas, Carlos ; Nik-Zainal, Serena ; Clarke, Robert B ; Nuciforo, Paolo ; Díez, Orland ; Serres-Créixams, Xavier ; Peg, Vicente ; Espinosa-Bravo, Martín ; Macarulla, Teresa ; Oaknin, Ana ; Mateo, Joaquin ; Arribas, Joaquín ; Dienstmann, Rodrigo ; Bellet, Meritxell ; Oliveira, Mafalda ; Saura, Cristina ; Gutiérrez-Enríquez, Sara ; Balmaña, Judith ; Serra, Violeta

United States

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Abstract 2817: Metabolic heterogeneity in breast cancer integrative clusters to screen metabolic vulnerabilities for diagnosis and treatment response

Ros, Susana ; Wright, Alan J. ; Bulat, Flaviu ; Greenwood, Wendy ; Hu, De-en ; Callari, Maurizio ; Chia, Ming Li ; Serra, Violeta ; Rueda, Oscar ; Bruna, Alejandra ; Caldas, Carlos ; Brindle, Kevin M.

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Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer

BOYER, John ; ALLEN, Wendy L ; MCLEAN, Estelle G ; WILSON, Peter M ; MCCULLA, Andrea ; MOORE, Stephen ; LONGLEY, Daniel B ; CALDAS, Carlos ; JOHNSTON, Patrick G

Philadelphia, PA: American Association for Cancer Research

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PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer

Cox, Orla T ; Edmunds, Shelley J ; Simon-Keller, Katja ; Li, Bo ; Moran, Bruce ; Buckley, Niamh E ; Bustamante-Garrido, Milan ; Healy, Nollaig ; O'Flanagan, Ciara H ; Gallagher, William M ; Kennedy, Richard D ; Bernards, René ; Caldas, Carlos ; Chin, Suet-Feung ; Marx, Alexander ; O'Connor, Rosemary

United States

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Abstract OT1-01-07: PIONEER- Pre-operative wIndOw study of letrozole plus PR agonist megestrol acetate versus letrozole aloNE in post-menopausal patients with ER-positive breast cancer

Kumar, SS ; Benson, J ; McIntosh, S ; King, P ; Dougall, G ; Kateb, A ; Vallier, A-L ; Jones, L ; Qian, W ; Provenzano, E ; Caldas, C ; Pantziarka, P ; Carroll, J ; Baird, RD

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A recurrent chromosome breakpoint in breast cancer at the NRG1/Neuregulin 1/Heregulin gene

HUANG, Huai-En ; CHIN, Suet-Feung ; GULLICK, William J ; JACQUEMIER, Jocelyne ; CALDAS, Carlos ; CHAFFANET, Max ; BIRNBAUM, Daniel ; EDWARDS, Paul A. W ; GINESTIER, Christophe ; BARDOU, Valérie-Jeanne ; ADELAÏDE, José ; GOPALAKRISHNA IYER, N ; GARCIA, Maria J ; POLE, Jessica C ; CALLAGY, Grace M ; HEWITT, Stephen M

Philadelphia, PA: American Association for Cancer Research

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Abstract 3503: Biomarkers for inhibitors of the replication stress response proteins WEE1 and ATR in triple negative breast cancer

Serra, Violeta ; Cruz, Cristina ; Lai, Zhongwu ; Castroviejo-Bermejo, Marta ; Palafox, Marta ; Polanska, Urszula M. ; Jones, Gemma N. ; Wang, Anderson ; Michopoulos, Filippos ; Brough, Rachel ; Dougherty, Brian ; Cadogan, Elaine ; Critchlow, Susan ; Bruna, Alejandra ; Barrett, J. Carl ; Saura, Cristina ; Lord, Christopher J. ; Caldas, Carlos ; Arribas, Joaquin ; Balmaña, Judith ; O’Connor, Mark J.

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Abstract 932: Reversing PARP inhibitor resistance by targeting the replication stress response

O'Connor, Mark J. ; Cruz, Cristina ; Castroviejo-Bermejo, Marta ; Polanska, Urszula M. ; Jones, Gemma N. ; Wang, Anderson ; Lai, Zhongwu ; Forment, Josep ; Bulusu, Krishna ; Llop-Guevara, Alba ; Dougherty, Brian ; Saura, Cristina ; Brough, Rachel ; Lord, Chris J. ; Bruna, Alejandra ; Caldas, Carlos ; Fawell, Stephen ; Barrett, J Carl ; Critchlow, Susan E. ; Balmaña, Judith ; Cadogan, Elaine ; Serra, Violeta

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